Ali Mohebi

My dad—arguably the best in the world—has sailed away. He was an advocate of science, a caring cardiologist, and a history enthusiast. He loved telling jokes and making people laugh. I will do the same: laugh and make laugh, until we meet in the deep blue... So it goes...

@iamsartorius Far too kind. ممنون از لطف شما

حدود هفت هشت ساعت سر پنل‌ها نشستیم ولی آخرین سخنرانی که نشستیم و میتونم بگم تنها پارتی بود که به شدت جذاب بود برام، سخنرانی دکتر علی محبی از آمریکا بود. واقعاً بینظیر بود همه چی؛ هم سخنرانی‌شون و هم کارشون! @mohebial

@dr_alexharris 10/10

They look pretty decent

@AndrewHires Brilliant. Have you tried feeding it your ND proposals (if you have one)? I want to know if the algorithm has an optimism bias or not. A functional algorithm should be able to somehow rank proposals...

Testing out DeepSeek-R1's ability to do "science" in one-shot. I asked it to critique my 2017 R01 proposal which was scored Impact 26, 10% percentile, and funded by NINDS. (I wrote the proposal, I have the rights to share it with anyone or anything). I uploaded a PDF of my Specific Aims and Research Strategy with the following, off-the-cuff prompt. It spit out a credible critique indistinguishable from a median quality reviewer's submission after 10 seconds of thought. Overall impact score 2. Thank you! If this is what a free tool can do TODAY in 10 seconds of inference, on the first shot with zero iteration in prompting or followup, what actual role are humans going to play in the process of science going forward? Would you rather have your multi-million dollar, career milestone proposal be critiqued by a super-intelligent AI agent, or by a tired, over-worked, potentially biased human? It seems quite plausible that generating new, evidence-supported hypotheses and experimental plans could already be better accomplished by frontier models (with or perhaps without human prompting) than by humans alone. What do we do now?

Indeed, it's an exciting new tool! Congrats to all. Cannot wait to start using the setup...

Pls chk out the Bruchas lab's new preprint "Endocannabinoids facilitate transitory reward engagement through retrograde gain-control". Congrats @DavidJMarcus2 @cloverpharm @StellaLab11 @Graphtablet & many other colleagues. biorxiv.org/content/10.110…

(1/7) Far-red dopamine sensor is coming! Excited to introduce our chemigenetic DA sensor, HaloDA1.0! #Dopamine #FarRedSensors, #GRAB biorxiv.org/content/10.110…

@NeuroTejeda Congrats, Hugo!

Excited to share work from Twitter less Juan Enriquez-Traba, grad student from the lab. Juan and the team demonstrate that dopamine regulates differential aspects of reward, motivation vs reinforcement, via co-expressed D3 and D1 receptors nature.com/articles/s4159…

Imagine your favorite top level admins at your school. Who court Epsteins to meet their next fundraising goals. Who care more about the alphabet initiatives than the people the alphabet belongs to. Those have taken control of the Democratic party. And sure, pardon your son.

Two favorite friends of mine talking science 😊

@dcardozopinto @Nature Congrats, Dannie!

My paper is out!! 🎉 "Opponent control of reinforcement by striatal dopamine and serotonin", @Nature Here, we show that dopamine and serotonin signals form a gas-brake system for reward in the mammalian brain 🧠 THREAD ⬇️ 1/n

The first piece of work from my PhD has now been uploaded to biorXiv! Short 🧵below:

An interview with him (in Farsi) where he shares some of his thoughts and ideas... youtu.be/TJgtHuJGgwo

Kindness trumps excellence. My dad, a farmer’s son who became a pioneering cardiology professor, was remembered after his passing not for his academic/career achievements but for his acts of kindness. It goes to show that kindness outlasts success. Kindness is timeless...

Thank you all for your messages. It takes a village to uplift sorrow. I feel so lucky to be surrounded by villagers...

My dad—arguably the best in the world—has sailed away. He was an advocate of science, a caring cardiologist, and a history enthusiast. He loved telling jokes and making people laugh. I will do the same: laugh and make laugh, until we meet in the deep blue... So it goes...

The Fountain is perhaps the best depiction, both visually and musically, of death and humanity's helpless struggle against it, ultimately leading to salvation through acceptance. Listen to the OST for me youtube.com/watch?v=C3skXj…

@bita137 Musk mentality much?