Bagnat Lab

Very interesting new preprint: ERC1 (ELKS/RAB6-Interacting/CAST Family Member 1)) as a candidate gene for craniofacial syndromes. "Regulated extracellular matrix trafficking shapes cell growth during cartilage morphogenesis" biorxiv.org/content/10.110… 1/n

Curious about how polarized targeting of proteins regulates lumen formation? Then make sure to check out Daniel Levic’s article in Seminars in Cell and Developmental Biology authors.elsevier.com/a/1elpf3si8Pr8…

Congrats Michel on promotion to full professor! 🍾 @DukeCellBiology

I am honored and delighted to be selected as one of the new #HHMIInvestigators. Excited about the future and the new discoveries ahead! Thank you for your support!

Also shout out to our awesome grad student, Siyao, who took this image!

We've also been having some fun imaging different tissues, such as the otic vesicle, using our ZO1-Tomato KI-fusion line. Movie credit: Daniel Levic

Check out our lab’s latest pre-print—> paper for a simple, efficient approach to generating KI-fusion lines in zebrafish! @Dev_journal doi.org/10.1242/dev.19…

One more #postdoc position is opening in the @BonifacinoJuan lab @NICHD_NIH to study #molecular mechanisms of #protein/#organelles #trafficking, #lysosomes, #autophagy, and related #diseases. For more info, tinyurl.com/s9bvczzk. Apply to email in the link. Please RT

Thoughtful review by @BagnatLab @DukeU. They propose that apical sorting in epithelial cells is not ruled by a protein-based sorting machinery, but relies on oligomerization, phase separation of lipids and proteins, and pH-dependent glycan interactions febs.onlinelibrary.wiley.com/doi/10.1111/fe…

Also thanks to Holger Knaut and Naoya Yamaguchi at Skirball/NYU for their contributions to this work as well!

Excited to share the lab’s latest preprint from postdoc, Daniel Levic! Here, we detail a simple approach for tagging proteins in zebrafish on their N- or C termini by inserting PCR-generated donor amplicons into non-coding regions of corresponding genes. biorxiv.org/content/10.110…

Curious about how epithelial cells precisely deliver proteins to either the apical or basolateral membranes? Then make sure to check out Daniel Levic’s article in FEBS re-examining how self‐organization and biophysical mechanisms guide apical sorting! febs.onlinelibrary.wiley.com/doi/10.1111/fe…

A big congratulations to Jamie Garcia @jamiegarcia1014 for successfully defending her thesis yesterday! Time to celebrate 🎉!

#Lightsheet imaging of zebrafish notochord and skeleton. Credit to @huiskenlab and @BagnatLab. #ZebrafishZunday

@BagnatLab and I- we are new American citizens- we voted for the first time in a Presidential Election TODAY! Go VOTE if you have not done so yet! It is very easy and safe! dcovotes.com/voters/voting/…

Please RT: @DukeCellBiology is hiring. The preferred level is for an Assistant Professor. Deadline October 15th. Apply through academicjobsonline.org/ajo/jobs/16932 @ASCBiology @BLACKandSTEM @sacnas @AWISNational @BlackInNeuro @AAAS_SEAChange @CienciaPR @nationalpostdoc

@Ken_Poss_Lab @Val_Cigliola Congrats everyone!

Tp53 Suppression Promotes Cardiomyocyte Proliferation during Zebrafish Heart Regeneration cell.com/cell-reports/f… Congrats Adam Shoffner, @Val_Cigliola, Nutishia Lee, Jianhong Ou, on a new heart regeneration story!

It was such a pleasure to have Vaishnavi in our lab while she was a high school student at NCSSM. Even though we miss having her in lab, we’re always excited to hear how she is using her passions to make an impact as a researcher at UNC!

Please RT: A postdoctoral position is available in the Eroglu and @BagnatLab laboratories at @DukeCellBiology Department. Interested individuals, please contact us via email with your CV and cover letter.

So, with excitement and some trepidation, I'm organising a virtual conference on mechanobiology. We have a great speaker line up and timed to make accessible to as many time zones as possible. Registration is open! mbi.nus.edu.sg/events/morphog…