Baudoin Research Group

We are happy to share that from now on we'll be posting exciting news from our group on Bluesky! 🧪 Same research 🧪 Same passion for catalysis and C-H activations 🧪 New platform! bsky.app/profile/baudoi… Follow us on Bluesky to stay updated on our latest work!

Exciting news from the 7th International Symposium on C-H Activations in Mumbai @ischa2024 ! Olivier delivered an inspiring lecture on direct Pd-catalyzed ring construction via C(sp3)–H activation. 🧪It was a pleasure and a great experience! #CHActivation #Chemistry

Exciting days for the Baudoin Group! 🎓 Maria & Andrea successfully defended their PhDs, making significant contributions to Pd, Ir, and Fe-catalyzed C-H functionalizations. Huge congrats to both, and best wishes for the future! 🚀👏 #BaudoinGroup #PhD #Chemistry #PhDone

Fe-Catalyzed alpha-C(sp3)-H Amination of N-Heterocycles (Olivier Baudoin and co-workers) @Baudoin_Group @UniBasel_en #openaccess onlinelibrary.wiley.com/doi/10.1002/an…

The list of most accessed papers in October includes contributions by @Baudoin_Group, @subohxx, @alexanderln91 - what else? ow.ly/j7WP50U4RBZ

Interested in C-H amination of pharmaceutically relevant motifs? You can use just FeCl2 as a catalyst for that. Our paper on Fe-catalyzed C(sp3)-H amination was published in Angewandte @angew_chem. Check it out here: onlinelibrary.wiley.com/doi/10.1002/an… #catalysis #Chemistry #amination

Pierre and Kseniia have joined our research group for their PhD studies! We are excited to have them on board and wish them a lot of success in their future projects!

Oleks just won the runner-up prize for the oral presentation of our recent total syntheses of Randainin D and Barekoxide at the SCS Fall Meeting 2024 in the Organic Chemistry section. Congrats Oleks! #OrganicSynthesis #SCS #FallMeeting @SwissChemistry

Can you complete the forward synthesis of (+)-Randainin D without seeing its structure? On the last #LCSOSynthesisProblem Christine challenged us with its synthesis by @Baudoin_Group in @J_A_C_S. Take a look: epfl.ch/labs/lcso/wp-c… Original paper: doi.org/10.1021/jacs.4…

Wonderful talk on palladium catalyzed C-H activation leading to complex fused ring systems. by @Baudoin_Group, the 2024 plenary lecturer @LIMA_UMR7042 spring day.

Plenary lecture by @Baudoin_Group on palladium catalyzed construction of fused ring systems. @LIMA_UMR7042 spring day 2024

Interested in cyclobutanes, azetidines and oxetanes?🔳 Check out our just-published paper on the synthesis of fused 4-membered rings enabled by 1,4-palladium migration! @J_A_C_S Read more here: pubs.acs.org/doi/10.1021/ja…

New approaches to #terpene synthesis: Researchers at @UniBasel_en present an innovative approach to producing these versatile natural substances, including those already used in #therapies for cancer, epilepsy, and malaria. unibas.ch/en/News-Events…

Synthesis of the Diterpenes (+)-Randainin D and (+)-Barekoxide via Photoredox-Catalyzed Deoxygenative Allylation | JACS @Baudoin_Group @UniBasel @TotalSynthesis @TotalSyntheses #Diterpene #Photoredox #Allylation pubs.acs.org/doi/10.1021/ja…

Our total synthesis of (+)-randainin D and (+)-barekoxide via photoredox-catalyzed deoxygenative allylation is now out in @J_A_C_S. You can find the article here: pubs.acs.org/doi/10.1021/ja… #TotalSynthesis

Our work on the studies towards the total synthesis of cryptowolinol is now out in @JOC_OL. The key step is a challenging enantioselective Pd0-catalyzed C(sp3)–H arylation, which proceeds via PKR. You can read more about it here: pubs.acs.org/doi/10.1021/ac…

Methylene C(sp3)-H Arylation Enables the Stereoselective Synthesis and Structure Revision of Indidene Natural Products (Olivier Baudoin and co-workers) @Baudoin_Group onlinelibrary.wiley.com/doi/10.1002/an…

Our work on the total synthesis of indidene natural products has been accepted in @angew_chem. To find out more about the methylene C(sp3)–H activation and structure revisions, you can read the article here: onlinelibrary.wiley.com/doi/10.1002/an…

We are currently looking for high-profile chemists to apply to SNSF Swiss Post-doctoral Fellowships. Please check our website for all details: baudoin.chemie.unibas.ch/en/application…

Our mechanistic studies on the effect of α-substitution on the reactivity of Pd-catalyzed C(sp3)–H activation has been accepted in @ACSCatalysis. You can read the paper here: pubs.acs.org/doi/10.1021/ac…