Waser Group

Great to be at the 59th Bürgenstock Conference #SCS_BC26 at the shores of beautiful Lake Lucerne 🏔️ ☀️ . Looking forward to a week full of outstanding science & inspiring discussions!

The work of @helsoleav @DuncanBrownsey and Hugo Senelle, on the alcohol-directed carboamination of enynes is now published in Angewandte Chemie ! doi.org/10.1002/anie.6…

A 4 year post-doc position is available in the Sutherland group to work on novel fluorescent amino acids and peptides. Closing date for applications is 26th May. See here for more details and how to apply: jobs.gla.ac.uk/job/research-a…

🌟 𝗧𝗵𝗲 𝗯𝗶𝗴 𝗼𝗻𝗲! So proud to finally being able to share the Opus Magnum of my PhD at Cramer lab - Out now @J_A_C_S. After 4+ years of solo development, the combo of pride, relief, and joy is hard to describe 🥲 @EPFL_CHEM_Tweet @NCCR_Catalysis pubs.acs.org/doi/10.1021/ja…

🦋 Strain-guided precision : Regio- and stereoselective lithiation unlocks highly strained 1-aza[n.1.0]bicycles, enabling controlled functionalization and rapid access to 3D heterocycles with exquisite diastereocontrol ⚡️ @J_A_C_S @VarinderAggar11 doi.org/10.1021/jacs.6…

2nd talk of @SwissChemistry Spring Meeting: @EvaHeviaGroup @DCBPunibern Eva Hevia presents „Unleashing the Power of Sodium for Arene Functionalisation and Catalysis“ @unifrChemistry

Our enantioselective synthesis of 1,3-BCHs as meta-benzene bioisosteres has been published in @NatureSynthesis! Great asymmetric strategy to construct phenyl mimics with retention of biological activity developed with @Carla__PS, Pablo and @TortosaLab! nature.com/articles/s4416…

Fluoro-Wacker Gem-Difluorination of Alkene via Fluoropalladation and Dyotropic Rearrangement | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/ja…

One-Pot Synthesis of Nitriles from Aldehydes Enabled by Amino-λ3-iodane. pubs.acs.org/doi/abs/10.102…

📢 Join next week’s #chembio seminar with Prof. Jayanta Chatterjee (Indian Institute of Science) @EPFL_en! 🎯 "From Helical Motifs to Oral Drugs: Design Principles for Bioavailable Macrocyclic Peptides" 🗓️ 🇨🇭 20.04.2026 | 14:15 › 15:15 🔗 Details: bit.ly/3MOjVjy

We have explored a new dimension of simple alcohol elimination. Check out our recent work by Pravin, Howard, and Ania in @J_A_C_S. @JagiellonskiUni, @NCN_PL. pubs.acs.org/doi/10.1021/ja…

We @WerzLab @FreiburgChem @UniFreiburg just published dimerizations of BCBs in @ChemicalScience We think that this is very important paper for the progress of BCB chemistry since it elucidates background reactions to occur in the presence of Lewis acids. pubs.rsc.org/en/content/art…

Cis-cyclopropanedicarbaldehydes - versatile but elusive building blocks - only with light and Lewis Acid catalysis from renewable resources. Out on Chemrvix. https://10.26434/chemrxiv.15001190/v1

Happy to contribute with a review to a Special Issue in honor of the brilliant scientist and good friend Prof. Pep Cornella @CornellaLab for the 2026 Tetrahedron Young Investigator Award "Macrocyclizations toward the Assembly of Tyr-Linked Cyclopeptides" sciencedirect.com/science/articl…

🌻Rest in peace, Günther Maier. The chemist who made one “impossible molecule” after another died on April 10 at the age of 94. A Swabian by birth, he began studying chemistry at TH Karlsruhe in 1952, today’s KIT. He worked with Rudolf Criegee and obtained his Diploma in 1957 and his PhD degree in 1959. After a postdoc at Johns Hopkins University @JohnsHopkins with Emil H. White, a pioneer in #photobiochemistry, Maier returned to the Criegee lab and completed his habilitation in 1964. His work then dealt with valence isomerization, a topic about which he wrote a legendary monograph. #Cyclobutadiene and #tetrahedrane were signature molecules of the Maier lab, which he established in Karlsruhe. From there he moved to the University of Marburg in 1970 and to the University of Giessen in 1978, where he remained until his retirement in 2000. Not only C₄H₄ but also C₁₀H₁₀ molecules fascinated Günther Maier and the wider chemistry community in the 1960s and 1970s, and he was a grand master of such reactive compounds. While his group isolated cyclobutadiene and tetrahedrane derivatives at room temperature, they also performed matrix-isolation #spectroscopy studies at extremely low temperatures in parallel. In this way, not only reactive hydrocarbon species could be detected, but also heteroatom molecules such as sila- and borabenzene, as well as disilene and disilyne. One could go on (see figure), but this must suffice to demonstrate the impact of Maier’s work on modern organic chemistry and beyond. More can be found in Maier’s autobiography, “Das war’s—Erinnerungen eines Doktorvaters” (l-i-c.org/1125), published in 2021. Günther Maier was a modest man who meticulously trained a large number of PhD students. His achievements were recognized with the Adolf von Baeyer Memorial Medal of the German Chemical Society. PS: His autobiography was the first volume in the “Lives in Chemistry” (LiC) book series, which would not exist without him. He and his former PhD student Karl Reuter were instrumental in starting LiC, which has since grown into a “library” of 15 volumes. Maier was a founding member and later an honorary member of the LiC Advisory Board.

Review on epothilones by Karl-Heinz Altmann in Helv Chim Acta onlinelibrary.wiley.com/doi/10.1002/hl…

Happy😃to share our Tutorial Review on strain-release driven reactions of bicyclobutanes, just out @ChemSocRev! Congratulations, @shiksha_deswal & @RCD07_IISC for the timely summary👏. We thank @serbonline for funding our work on BCBs🙏! @iiscbangalore pubs.rsc.org/en/content/art…

@HariGroupIISc @ChemRxiv @J_A_C_S Thanks Durga!

@LcsoLab @ChemRxiv @J_A_C_S Congratulations, LCSO!! Cool transformation!

From @ChemRxiv to @J_A_C_S ! Our work on housanes is now published!

@nayan_group @ChemRxiv @J_A_C_S Thanks!

@LcsoLab @ChemRxiv @J_A_C_S Congratulations for developing strategy of this interesting molecules!

We are hiring. We are looking for post-doctoral fellow to join the group. If interested please contact me by email.