Madelyn Hjort
43 posts
Madelyn Hjort
@BrainMadelyn
Postdoc @UMNeurosci PhD from @UW_Neuroscience in Stuber Lab B.S. Neuroscience / Genetics from @umncbs
Minneapolis, MN Katılım Nisan 2020
146 Takip Edilen226 Takipçiler
Very excited for this opportunity! So proud of all the wonderful people in my lab that make this possible!
@KlingensteinOrg@klingensteinorg
Congratulations Vijay Mohan K Namboodiri, Ph.D., recipient of a Klingenstein-Simons Fellowship in Neuroscience for the project “Neural circuit mechanisms underlying retrospective learning.” @vijay_mkn @SimonsFdn
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Thanks Michael! Excited to share that my work on the nociceptin opioid sensor is now published in @NatureComms. Thanks to the @tpatriarchi lab (and especially my co-first author Xuehan) for all of the hard work on this collaboration!
mbruchas@mbruchas
Chk out our newest collab paper co-led w/ @tpatriarchi, & others. We developed & characterized a nociceptin opioid peptide sensor. Congrats to Xuehan, @carriestineUW (student in my lab) who co-led effort. DM to try. @NIMH @NIDAnews @NAPECenter Link: nature.com/articles/s4146…
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Incredibly thankful to have had an opportunity to work on this project. I learned so much from @SodenLab and had a great time picking apart the VTA! Check out this thread to learn more about input specific regulation of VTA cell types 👇
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@vijay_mkn way to go vijay! can't wait to see more great things come out of your lab
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Very excited to be named among this group of amazing scientists! So proud of all the wonderful people in my lab that make this journey possible!
Pew Health@pewhealth
NEW: We're excited to announce the 37 researchers joining our 2024 class of scholars and fellows! 👏 Through their research into brain cancer, respiratory infections, antibiotic resistance, and more, these scientists will help advance biomedical research. pew.org/4boDcSt
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Happy to have been a small part of this work! Congrats @outRaajeous and @mbruchas on a real tour de force on dynorphin signaling in striatum.
Raaj Gowrishankar@outRaajeous
Excited to share our work in the @mbruchas lab on how endogenous opioids promote goal-directed behavior, funded by @NIDAnews. I am currently on the job market and this work will form the basis of my research program. biorxiv.org/content/10.110…
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@PiantadosiSean @mbruchas @ProfJohnARogers @MinKyuLeePhD @MingzhengWu @NeuroLuxInc @AvilaROAD @NUro_science yay Sean!
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Excited to share work from @mbruchas & @ProfJohnARogers labs led by myself, @MinKyuLeePhD and @MingzhengWu with help from @NeuroLuxInc, @AvilaROAD, @NUro_science, and Dr. Yonggang Huang. Here we describe a device for combined intracranial drug delivery and fluorescence recording.
bioRxiv Neuroscience@biorxiv_neursci
An integrated microfluidic and fluorescence platform for probing in vivo neuropharmacology biorxiv.org/cgi/content/sh… #biorxiv_neursci
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@tychoi5667 @gstuber @Labrigger @outRaajeous We haven't tried. I suspect miniscopes will need some modifications to the focus mechanism before they are compatible- we talk about this a bit in the discussion section of the paper. It seems possible for sure!
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@gstuber @Labrigger @BrainMadelyn @outRaajeous Awesome!!! Is it also working with the microendoscope?
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I watch this video at least a couple times a week. It never gets old. Prisms + @Labrigger Cousa objective are game changers for striatal imaging. Congrats @BrainMadelyn @outRaajeous et al.
Madelyn Hjort@BrainMadelyn
Excited to share our methods work out in #Neurophotonics today! We coupled a new microprism design with a long working distance objective to track thousands of cells across days in the striatum. doi.org/10.1117/1.NPh.…
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@tychoi5667 We haven't tried. I suspect miniscopes will need some modifications to the focus mechanism before they are compatible- we talk about this a bit in the discussion section of the paper. It seems possible for sure!
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@BrainMadelyn Hi, My name is Tae-Yong Choi and I am a researcher at Korea Brain Research Institute at South Korea. It is very interesting results and an awesome vidoe!!! I have a simple question. Is this microprism working with the microendoscope (from Inscopix or UCLA miniscope)?
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Excited to share our methods work out in #Neurophotonics today! We coupled a new microprism design with a long working distance objective to track thousands of cells across days in the striatum.
doi.org/10.1117/1.NPh.…
GIF
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@outRaajeous @DavidJMarcus2 This! Such an endorsement! Thanks David
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I have a feeling this one is really going to set the standard for 2-photon imaging. Also, can’t speak highly enough about lead authors @BrainMadelyn and @outRaajeous
Madelyn Hjort@BrainMadelyn
Excited to share our methods work out in #Neurophotonics today! We coupled a new microprism design with a long working distance objective to track thousands of cells across days in the striatum. doi.org/10.1117/1.NPh.…
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I had an incredible rotation last summer in the @gstuber lab learning cutting-edge imaging from @BrainMadelyn - made it an easy decision to join the lab! Excited for what’s to come.
Madelyn Hjort@BrainMadelyn
Excited to share our methods work out in #Neurophotonics today! We coupled a new microprism design with a long working distance objective to track thousands of cells across days in the striatum. doi.org/10.1117/1.NPh.…
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@Labrigger @LucyTian828 @OptoSigma @pacificoptica thank you so much! excited to see what people do with the cousa next
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@BrainMadelyn @LucyTian828 @OptoSigma @pacificoptica Thanks for showing how well it works in this application. That's beautiful data, and a very nicely detailed technical write up. Super impressive!
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@___AshleyH Thanks! Honestly that's how I feel every time I watch this video (which is frequently😅)
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Also thanks to coauthors @LucyTian828 and Adam Gordon-Fennell, @optosigma for prism design assistance, and @pacificoptica who made the Cousa long working distance objective we used
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@outRaajeous @mbruchas @gstuber @NIDAnews A great co-leader! Grateful to have shared this project with you
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Excited to have co-led this effort with the talented @BrainMadelyn, where we detail the development and use of new microprims for longitudinal 2p calcium imaging in the striatum. Thank you to @mbruchas and @gstuber for the guidance and @NIDAnews for funding!
Madelyn Hjort@BrainMadelyn
Excited to share our methods work out in #Neurophotonics today! We coupled a new microprism design with a long working distance objective to track thousands of cells across days in the striatum. doi.org/10.1117/1.NPh.…
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Our paper includes a surgical protocol and ordering information! Have more questions? We’re happy to answer them.
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Thanks to @gstuber and @mbruchas for believing in this idea, @outraajeous for his willingness to help me try this out, @vijaymkn for sharing his PFC GRIN dataset and surgical expertise, @AlexLegariaM @LexKravitz @jones_g_parker and Ben Yang for sharing their DS GRIN dataset...
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