Rhiana C Simon, PhD

UW NAPE Center is hosting another outstanding imaging and genetics workshop this Fall. Geared towards new graduate students and postdocs. Please consider applying if you are interested!

How does the brain link a novel food to illness that happens later? We found that acetylcholine, released in part by parabrachial Calca neurons, can work through GPCRs in central amygdala to bridge the gap. New preprint from @gstuber + Palmiter labs: biorxiv.org/content/10.648…

A new study finds that both fear conditioning and antidepressant treatment stimulate new neuron growth in adult mouse brains, suggesting a possible adaptive response to stress-inducing experiences as well as elevated serotonin. scim.ag/4v59Hj7

Congratulations to Corey Harwell, PhD, on receiving a Neurobiology of Brain Disorders Award from the @McKnightFdn. His research explores how brain circuits develop and function, with implications for understanding neurodevelopmental disorders. #UCSFProud tiny.ucsf.edu/wu7qcH

Restaurants, billboards, commercials… what brain circuits link context to appetite? 🧠🍽️ Very happy to share a major update in our work on the hippocampus and lateral septum in calibrating food consumption! 🍩 Major thanks to our lab/collaborators! ⭐️ cell.com/neuron/fulltex…

@muruganmalu @gstuber Thank you so much! So glad that it's officially wrapped up~

Congratulations @gstuber and Rhiana! Beautiful work. Excited to see this out.

Thanks to @westonfleming for the ephys, @brandy_briones for the behavior help, @KenIshii1223 and Sam Golden for the lightsheet data, and everyone else who chipped in along the way. Finally, thanks to @gstuber for his guidance and support throughout this project!

Thrilled to announce that our paper is now finally out! 🎉We combine scRNAseq, 2p imaging, ephys, and behavior to understand the role of lateral septal Nts neurons in opioid withdrawal. Curious about the septum and addiction? Give it a read👇 cell.com/neuron/fulltex…

New paper on arousal in the brain! What controls the controller?

Want to compare social and nonsocial reward seeking behavior? 
On STAR Protocols, we provide instructions for the assembly of a 2 choice operant chamber with an easy to use GUI-based acquisition system. Low cost and fully automated @STARProtocols #sec8" target="_blank" rel="nofollow noopener">sciencedirect.com/science/articl…

I am thrilled to announce that I have been selected as an A.P. Giannini Postdoctoral Fellow! 🥳 Feeling fortunate to have received funding for my work on neurodevelopment of the lateral septum

Excited about our minisymposium at @SfNtweets ! Join us Wednesday afternoon to hear about the functional organization of lateral septum - from molecules to circuits and computations! Session details here: abstractsonline.com/pp8/#!/20433/s… #sfn2024

Chk out our newest collab paper co-led w/ @tpatriarchi, & others. We developed & characterized a nociceptin opioid peptide sensor. Congrats to Xuehan, @carriestineUW (student in my lab) who co-led effort. DM to try. @NIMH @NIDAnews @NAPECenter Link: nature.com/articles/s4146…

Incredibly thankful to have had an opportunity to work on this project. I learned so much from @SodenLab and had a great time picking apart the VTA! Check out this thread to learn more about input specific regulation of VTA cell types 👇

Thrilled to show my recent work about the regulation of dorsolateral septum GLP-1R neurons on feeding behavior. In this work, we showed that dLS-GLP-1R neurons and the inhibitory pathway to LHA can regulate feeding behavior. biorxiv.org/content/10.110…

Excited to share our methods work out in #Neurophotonics today! We coupled a new microprism design with a long working distance objective to track thousands of cells across days in the striatum. doi.org/10.1117/1.NPh.…

Please check our newest study on @biorxivpreprint - a tour de force led by the phenomenal @Chris_M_Reid, describing the diversity of neurons in the lateral septum in terms of transcriptomics, anatomical distribution, connectivity and electrophysiology: biorxiv.org/content/10.110…

Please apply to join my lab at Research Triangle Institute in North Carolina! We are seeking Ph.D. level scientists to join our team to work on mitochondrial mechanisms in substance use disorders. Apply here (or please RT/share): careers.rti.org/jobs/11456?lan…

We are currently hiring postdocs with experience in rodent models. Ephys and viral techniques a plus. Please DM me or email Opendak@kennedykrieger.org if interested!