Brandán Pedre

🧪🧬 New preprint! What if the same biosensor could reveal how cysteine is regulated across life domains? We introduce Cystector, a genetically encoded fluorescent biosensor for real-time cysteine monitoring in living cells. biorxiv.org/content/10.648… 🧵A thread ⬇️

Want to monitor cysteine dynamics in real time and with subcellular resolution? Cystector plasmids are now on Addgene! E. coli (His-tagged):addgene.org/250652/ Mammalian cells:addgene.org/250653/ Yeast:addgene.org/250654/ Yeast mitochondrial:addgene.org/250655

@ZeidaAri thank you very much Ari!

@Brandanium congrats Brandan!

🧪🧬 New preprint! What if the same biosensor could reveal how cysteine is regulated across life domains? We introduce Cystector, a genetically encoded fluorescent biosensor for real-time cysteine monitoring in living cells. biorxiv.org/content/10.648… 🧵A thread ⬇️

If you work on: #redoxbiology #metabolism #ferroptosis #mitochondria #biosensors …and want to monitor cysteine dynamics in your system, Cystector might help (🧬 Plasmids soon available on Addgene!). Happy to discuss applications or adaptations-DMs welcome!

Across systems, Cystector enables: • live-cell measurements • subcellular resolution • cross-domain comparisons • minimal perturbation of metabolism

Check out our latest research from the VIB-VUB Messens Lab🥳 In collaboration with the ULB Gurzov lab, we've applied a fluorescent biosensor to assess glycolysis and specifically quantify fructose-1,6-bisphosphate in liver cells🧪🔬 Amazing work @Israelhabanero 👏

Evidence-based sports supplements: A redox analysis sciencedirect.com/science/articl… In our recent review, we describe the redox properties of the sports supplements labeled as effective by the IOC 1.Bicarbonates 2.Beta-alanine 3.Caffeine 4.Creatine 5.Nitrates 6.Carbohydrates 7.Proteins

@Sulfur_Vladi @mpi_polymer @graeter_mbm @STakaaki26424 @RedoxDKFZ @FedorovaLab Congrats Vladi! Looking forward to seeing your new research!

My first day at @mpi_polymer as a group leader. Happy to become part of the family. Thanks to Frauke Graeter @graeter_mbm for her support and trust in me. Many thanks to my mentors @STakaaki26424 @RedoxDKFZ @FedorovaLab, Juergen Arnhold and Oleg Shadyro. Stay tuned!

@YusukeNasu1 @IBCSinica @AcadSinica Congratulations! All the best in your new position!

Starting this September, I'll be leading my own lab at @IBCSinica @AcadSinica! We'll use protein engineering to develop innovative fluorescent biosensors for studying cellular metabolism.

@ElizabethVeal9 It was an amazing conference! Thank you very much @ElizabethVeal9 and Carolin for the organization, we learned a lot and had a lot of fun! Looking forward to the 2026 GRC!

Will miss this view -and the wonderful scientific community that congregated at 2024 Thiol-Based Redox Regulation and Signaling GRC in Castelldefells. Hoping to see you all again in 2026!

Thanks a lot for the invitation. We were happy to explain why catenated sulfur chain species - supersulfides matter in biology! @STakaaki26424 @HozumiMotohashi @TetsuroMat25054 Small summary bellow:

@tonnomartinez Thank you Antonio! Hope it is useful :)

@Brandanium Great work, Brandán! 👏😃

Excited to share my latest review on genetically-encoded fluorescent redox biosensors! 🧬✨🧪🔬. Free to access until 23rd August following this link authors.elsevier.com/a/1jNDOw0NWL9V