Brian S. Alper, MD, MSPH, FAAFP, FAMIA

The FORCE Returns as a basis for success: Focus On Relentless Consistency and Excellence... linkedin.com/pulse/force-re…

@laila_22100 354 to the 11th power

99.9% will fail..!! Tell me the number that is bigger than this..??

Evidence-based medicine on FHIR augments the standards-based approach to digital health research academic.oup.com/jamia/article-…

@DonaldTNews Yes

@RobertKennedyJr @realDonaldTrump I have decades of experience developing and scaling systems for evidence based health decision support but how can that be shared for HHS?

Thank you @realDonaldTrump for your leadership and courage. I'm committed to advancing your vision to Make America Healthy Again. We have a generational opportunity to bring together the greatest minds in science, medicine, industry, and government to put an end to the chronic disease epidemic. I look forward to working with the more than 80,000 employees at HHS to free the agencies from the smothering cloud of corporate capture so they can pursue their mission to make Americans once again the healthiest people on Earth. Together we will clean up corruption, stop the revolving door between industry and government, and return our health agencies to their rich tradition of gold-standard, evidence-based science. I will provide Americans with transparency and access to all the data so they can make informed choices for themselves and their families. My commitment to the American people is to be an honest public servant. Let’s go!

@TheSGEM @AlanPlotzker @srrezaie @BMJ_EBM My email address is now balper@computablepublishing.com

@AlanPlotzker @srrezaie @BrianAlperMD @BMJ_EBM Dr. Alper is the corresponding author on the paper. Perhaps you could send him an email expressing your concerns. I’ve not seen him be very interactive on Twitter but he has replied to my emails. balper@ebsco.com

BALANCED REVIEW: What is the clinical effectiveness of systemic #thrombolysis by #alteplase in patients with AIS if administered within 3hrs and 3 to 4.5hrs from symptom onset? bit.ly/3Mx1o8H #FOAMed #neurology PING @TheSGEM

@4mmk36 @BrianAlperMD @stroke_journey @BrianAlperMD’s work controlled for baseline differences & did the analysis per the original protocol failing to demo superiority. That means no RCTs in that time window tPA v placebo and subgroup analyses SRMA & obs study. Result is a degree of uncertainty.

#EBRconf2021 Joanne Dehnbostel Interoperable and Computable EBM on FHIR (Fast Healthcare Interoperability Resources) Cc @BrianAlperMD

#EBRconf2021 Andrey Soares on "Making Science Computable: Evidence-Based Medicine on Fast Healthcare Interoperability Resources (EBMonFHIR)" . Examples are continually created at fevir.net in both human and machine-readable formats. Cc @BrianAlperMD

I am a FHIR North 2021 Speaker -- presenting Making Science Computable: Evidence Based Medicine on FHIR #FHIRNorth #FHIR # EBMonFHIR #EBM #FEvIR #computableevidence #computablepublishing

A great foundational step to mobilize computable biomedical knowledge #MCBK #EBM #EBMonFHIR #COKA #ComputablePublishing -- just published at onlinelibrary.wiley.com/doi/epdf/10.10…

I just uploaded “2-minute Elevate Prize SKAF 2021-04-28.mp4” to #Vimeo: vimeo.com/542615539

2-minute video to introduce the origin of Scientific Knowledge Accelerator Foundation #EBM #COKA #computablepublishing

I just uploaded “FEvIR 3-minute intro 2021-04-18.mp4” to #Vimeo: vimeo.com/538297128

I just uploaded “FEvIR intro 3 minutes 2021-04-18” to #Vimeo: vimeo.com/538289068

Now published a key step in Making Science Computable: doi.org/10.1016/j.jbi.… #computable #evidence #publishing @ComputableP

Now you can access the full text of the final version here: jclinepi.com/article/S0895-… Developing #trustworthy #recommendations as part of an #urgent response (1-2 weeks): a #GRADE concept paper.

Developing #trustworthy #recommendations as part of an #urgent response (1-2 weeks): a #GRADE concept paper. Hoping to contribute to managing the #COVID19 crisis jclinepi.com/article/S0895-… @schunemann_mac @allgreatcolleagues

COVID-19 Knowledge Accelerator (gps.health/covid19_knowle…) launches Code System Development efforts (docs.google.com/document/d/1R6…) for Risk of Bias, Study Design, Statistic Type and Statistic Model code systems

The End of an Era — DynaMed® Founder Begins New Chapter health.ebsco.com/blog/article/t… via @EBSCO_Health @ComputableP #EBMonFHIR #COKA

@ComputableP for Computable Publishing LLC on Twitter