Brian Chan

RT @billbarnwell: I wrote about Brian Callahan last night. Don't want to see people get fired, but there weren't many signs of progress in…

Bacteria before and after vancopime #IDtwitter

@PaulSaxMD @robertpdickson There have also been studies like this showing higher mortality for pip-tazo in MSSA bacteremia; wonder if the anaerobic theory explains why! academic.oup.com/ofid/article/6…

Terrific thread on a fascinating study with potential high clinical impact for those who do hospital-based care. Thank you, @robertpdickson! Is depletion of anaerobes the mechanism of cefepime's superiority over pip-tazo? (Cefepime has anaerobic activity, albeit not as broad)

@eeeejjjaaaa My sweet home! Going for a dip?

@MattGlassman312 Thanks Matt, wasn’t easy to fit in rfk jr’s ASSVAC

@BrianTanChan Amazing.

Humbled to announce that I have been selected to serve on RFK Jr’s presidential campaign team as a member of the American Safe and Secure Vaccine Advisory Committee (ASSVAC)! Our committee certainly has folks with unorthodox viewpoints, so can’t wait to learn!

@yoshkapundrick Hey you got a problem with my ASSVAC

@BrianTanChan Junior couldn't get elected dogcatcher.

RT @PaulSaxMD: Not only is my ID colleague @BrianTanChan very funny, but he can spin an April 1st post better than anyone

@JakeJohnsonMD @jeffpears0n @KatyBowmanMD I meant providencia is r to omada

@JakeJohnsonMD @jeffpears0n @KatyBowmanMD I think omada is inherently r to providencia and its pals proteus and morganella

Alright #IDTwitter, what would you recommend in the situation below? Source control unattainable, infected graft so hoping for short-term acute treatment and long-term suppression. NDM positive Providencia rettgeri

@sigal_md @PaulSaxMD Yes, agree w you and Jake. that’s the problem — it’s hard to give clear guidance to teams on when to treat (and empirically cover for a history of previous coryne) other than ‘vibes.’ But it does feel like we are way over-treating

@BrianTanChan @PaulSaxMD 🤷🏻‍♀️ like other colonizers in copd/other chronic/nosocomial lung disease hard to know when just selected by our resp abx, a marker of a bad situation, or its cause. Agree it’s often just there for the ride., but some report presumed lower tract infxn e.g wwwnc.cdc.gov/eid/article/28…

When did we all decide C. striatum was a respiratory pathogen in immunocompetent ppl? Did I miss a meeting? Everyone's on vanc & I'm not sure this is helping. #thanksMALDITOF #IDTwitter @PaulSaxMD

@AMTatara Is there still 9 o’clock meal?

Been too long since I’ve been overnight at MGH; treated myself to a house staff cocktail…

@PaulSaxMD @JakeJohnsonMD Not tolerating metro at all, PO for sure and probably not IV. So it’s likely meropenem if I really want to cover these.

@BrianTanChan @JakeJohnsonMD Interesting question! I would, unless there's a contraindication. Basing this on the molecular studies of brain abscess that find a whole load of organisms that are never cultured. How do we know they're all susceptible to beta lactams? An early example: doi.org/10.1093/cid/ci…

Brain abscess with strep, odontogenic source. Healthy young man otherwise. Am I obligated to treat with flagyl for anaerobes too? Shouldn’t the anaerobes all be mouth flora? #IDTwitter @PaulSaxMD @JakeJohnsonMD

@dhopkins1776 Wow! Congratulations Dan!

Honored & excited about this. Deep thanks to the committee--and of course to the book's readers.

@IDDocJen @MGHBWHIDFellows @bwh_id @AlisseHannaford @nicole_rebusi @BWDionne @jeffpears0n Them: we suspect bacterial superinfection, can we have ceftol/tazo?

Beginning of a horror story #IDTwitter

@MattGlassman312 Give Sugar, Copper Blue a spin

Listening to a lot of 90s records with my girls recently. An album that’s better than I remember is Cracker, Kerosene Hat. An album that’s worse than I remember is Soul Asylum, Let Your Dim Light Shine.

Good news @PaulSaxMD HAART means something else now