Bruno Ramos-Molina, PhD

We are thrilled to share that the 49th SEBBM Congress will be held in Murcia in 2027! Huge thanks to @SEBBM_es for trusting our proposal. We can’t wait to start organizing this inspiring meeting! 🎉 @FFIS_CARM @IMIB_RMurcia @UMU @UCAM @UPCToficial @MANunezSanchez @AnaBPerezOliva

The microbial tryptophan metabolite indole acts on the gastrointestinal tract to improve glucose homeostasis in a mouse model of #diabetes by enhancing GLP-1 secretion and L cell differentiation @DiabetologiaJnl link.springer.com/article/10.100…

Roseburia inulinivorans increases muscle strength #sarcopenia #aging #microbiota @Gut_BMJ gut.bmj.com/content/early/…

Hypothalamic endoplasmic reticulum stress drives pubertal precocity due to early-onset #obesity in female rodents @PNASNews pnas.org/doi/10.1073/pn…

Immune cells regulate circulating adipocyte extracellular vesicle levels in response to metabolic shifts #obesity #diabetes @Cell_Metabolism cell.com/cell-metabolis…

Plasma GDF15 increases during hyperinsulinemic hypoglycemia in humans with post-bariatric hypoglycemia and after insulin exposure in mice #obesity #RYGB cell.com/cell-reports-m…

Hyperpolarized [U-2H, 2-13C]Fructose Distinguishes Direct Hepatic Gluconeogenesis Through Fructose-1-Phosphate Production in Fed and Fasted States #Metabolism @acsbiol pubs.acs.org/doi/10.1021/ac…

HIF-2α induction in de novo lipogenesis in #MASH is dependent on IL-21 signaling @jbiolchem jbc.org/article/S0021-…

Microbiota-mediated induction of beige adipocytes in response to dietary cues #obesity #metabolism @nature nature.com/articles/s4158…

GPR146 in adipose tissue drives adipose-liver crosstalk and promotes hepatic steatosis in mice #MASLD @NatureComms nature.com/articles/s4146…

@Sustantivado No te queda na 🤣

Mira que me encanta mi trabajo pero qué poco me pagan para todo lo que hago

@doctorsaluja @IMIB_RMurcia @_ibima There is preclinical evidence that indicate that SCFAs has beneficial effects directly on the liver. Clinical evidence is still lacking although several trials are currently ongoing 😉

@Brunorm84 @IMIB_RMurcia @_ibima Would clinically supplementing butyrate help manage #MASLD?

I am delighted to share our latest systematic review published in Current Obesity Reports on the role of #butyrate in people with #MASLD. A great collaboration between @IMIB_RMurcia & @_ibima. Congratulations to all the authors for their outstanding work!! link.springer.com/article/10.100…

@drshafikuchay Thank you friend ☺️

Congratulations @Brunorm84 👏🏼👏🏼

@jcfergarcia @MANunezSanchez @QueipoMi

Targeting #microbiota-generated acetaldehyde to prevent progression of #MASLD @Cell_Metabolism cell.com/cell-metabolis…

Human #MASLD is a diurnal disease driven by multisystem insulin resistance and reduced insulin availability at night @Cell_Metabolism sciencedirect.com/science/articl…

Hepatocyte PLAGL2 deficiency alleviates #MASH through MYD88-licensed inactivation of inflammasome @CellReports cell.com/cell-reports/f…

CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly #MASLD @Nature nature.com/articles/s4158…

Lack of PCK1 in hepatic stellate cells causes liver fibrosis by fueling tricarboxylic acid cycle and increasing glycolysis @Cell_Metabolism sciencedirect.com/science/articl…

Male #obesity causes adipose mitochondrial dysfunction in F1 mouse progeny via a let-7-DICER axis @NatureComms nature.com/articles/s4146…