Christopher Nötzel

431 posts

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Christopher Nötzel

Christopher Nötzel

@C_Noetzel

Dr. Chrischi, PostDoc @ Striepenlab, UPenn, interested in gene regulation & differentiation of eukaryotic pathogens. Damon Runyon Fellow. BoP student 2019. 🇩🇪

Philadelphia, PA Katılım Eylül 2017
461 Takip Edilen542 Takipçiler
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Christopher Nötzel
Christopher Nötzel@C_Noetzel·
Check out our new Spotlight article @TrendsParasitol, where we showcase the amazing Malaria Cell Atlas project lead by @marakat @sangerinstitute
Trends in Parasitology@TrendsParasitol

In this new Spotlight, Drs @C_Noetzel & @KafsackLab @WeillCornell highlight the recent @NatureComms article on #SingleCell #transcriptomics of #Plasmodium #falciparum from @drjakebaum @marakat @imperialcollege @sangerinstitute Free access at authors.elsevier.com/a/1dZNP5Eb1x7s…

Manhattan, NY 🇺🇸 English
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CryptosporidiumMtgUK2026
CryptosporidiumMtgUK2026@CryptoUK26·
Registration and abstract submission is now open for the 2nd Biennial Cryptosporidium Meeting is now open. Deadline April 1st: eventbrite.co.uk/e/2nd-biennial… Submit your abstract by Feb 15th. See you in Edinburgh May 24th-26th, 2026!
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Boris Striepen
Boris Striepen@striepenlab·
Cryptosporidium genetics really works! Latest cross explains why tb drug failed in crypto clinical trial. Widespread genomic heterogeneity at the type II NAD(P)H dehydrogenase locus predisposes Cryptosporidium to clofazimine resistance @millseba biorxiv.org/content/10.110…
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Boris Striepen
Boris Striepen@striepenlab·
Clearly the ⁦@SaterialeLab⁩ is on a nice roll with another terrific screening paper in Cryptosporidium: Targeted CRISPR screens reveal genes essential for Cryptosporidium survival in the host intestine | Nature Communications nature.com/articles/s4146…
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Francesca Florini
Francesca Florini@fra_florini·
So proud of this work finally out! We examined antigenic variation at single-cell level and found a lot of unexpected diversity. Make sure to check it out and, if you are at #BioMalPar this week, don’t miss my talk on Thursday #EMBLMalaria
Nature Microbiology@NatureMicrobiol

Out Now! scRNA-seq reveals transcriptional plasticity of var gene expression in Plasmodium falciparum for host immune avoidance bit.ly/4jZUM4h #scRNAseq #transcriptomics #malaria

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Sateriale Lab
Sateriale Lab@SaterialeLab·
Cryptosporidium modifies intestinal microvilli through an exported virulence factor! (full thread in the other place) biorxiv.org/content/10.110…
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Boris Striepen
Boris Striepen@striepenlab·
Yet another study showing the poor efficacy of currently available cryptosporidiosis treatment. We urgently need better drugs! Effect of Nitazoxanide and Probiotic Treatment on Bangladeshi Children with Cryptosporidiosis in AJTMH ajtmh.org/view/journals/…
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Christopher Nötzel
Christopher Nötzel@C_Noetzel·
Christmas gift - not sure if my girlfriend is trolling my job or approving of my love for parasites, but either way I love it 😃
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VEuPathDB
VEuPathDB@veupathdb·
Welcome back! VEuPathDB resources are back online today! We will continue to provide bioinformatics services under a new organizational structure. Read more here: #future" target="_blank" rel="nofollow noopener">veupathdb.org/veupathdb/app/…
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Boris Striepen
Boris Striepen@striepenlab·
So proud of ⁦@millseba⁩ Sebastian Shaw and his great work on Cryptosporidium crosses to understand parasite persistence.
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Ryan Pardy
Ryan Pardy@RyanPardy2·
Please RT! The Pardy Lab is hiring! Looking for graduate students who are interested in learning about the role of IFN-γ in intestinal immunity. Great opportunity to be a part of a new lab from the beginning! Projects, contact, and more info below! inrs.ca/en/research/pr…
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Boris Striepen
Boris Striepen@striepenlab·
Read all about the CD4+ T cell response to Cryptosporidium from @iancohn graduate work in our new paper in @JExpMed. Out today! Sending pathogenesis factors into the host cell comes at a price: you get noticed as an antigen.
Journal of Experimental Medicine@JExpMed

Cryptosporidium is a major cause of diarrheal disease worldwide. @iancohn @striepenlab @KingOfPathogens et al engineer transgenic C. parvum to express MHCII-restricted model antigens & dissect priming & effector functions in parasite-specific CD4+ T cells hubs.la/Q02zfV7t0

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Shaw Sebastian
Shaw Sebastian@millseba·
Why is parasite sex sexy? academic.oup.com/jid/article/do… "Understanding parasite sex is at the very heart of understanding Cryptosporidium and how it continuously adapts to its changing hosts. Parasite sex also offers a powerful experimental tool for discovery" @JIDJournal @striepenlab
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Boris Striepen
Boris Striepen@striepenlab·
Our article on transcriptional control of the Cryptosporidium life cycle out today in @nature. Tremendous body of work by @DrKatelynWalzer, defining (among many other things) how parasites choose to be male. Read the paper at nature.com/articles/s4158…
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