Chris Lapointe
63 posts
@C_P_Lapointe
RNA biochemist #firstgen | Assistant Professor, @FredHutch @HutchBasicSci | Dale Frey Scientist, @DamonRunyon | https://t.co/zWwOqUgN3l
Architecture and flexibility of native kinetochores revealed by structural studies utilizing a thermophilic yeast biorxiv.org/cgi/content/sh… #biorxiv_biophys
Fresh out of the oven, our collaboration with the Kopito Lab - UFL1(E3) modifies, binds to, and dissociates the 60S subunit from the Sec61 translocon! #ribosome #cryoEM
Magnetic Isolation and Concentration (MagIC)-cryo-EM is a new method to enable direct structural analysis of targets captured on nanomagnetic beads, which requires only 0.0005 mg/mL of targets in 100 µL crude solution to make 10 cryo-EM grids. I will explain the magic behind it!
We are incredibly excited to welcome our newest faculty member, @ArmrYshr, on his first day in Basic Sciences @FredHutch! The Arimura Lab will study how chromatin functions, how it’s regulated, and what goes wrong in diseases like cancer. Learn more: research.fredhutch.org/arimura/en.html
We are incredibly excited to welcome our newest faculty member, @ArmrYshr, on his first day in Basic Sciences @FredHutch! The Arimura Lab will study how chromatin functions, how it’s regulated, and what goes wrong in diseases like cancer. Learn more: research.fredhutch.org/arimura/en.html
Monitoring mRNA dynamics after DDX3X depletion indicates translation suppression followed by mRNA stabilization, with GC content in the CDS being a strong predictor of mRNA stabilization ➡️ embopress.org/doi/full/10.10… @translatomics @CalvielloLab @humantechnopole #RNAbiology
We’re thrilled to announce the launch of SPARK, a year-long research internship program designed to provide outstanding college graduates from backgrounds underrepresented in STEM (as defined by the NIH) with the training and mentorship to become leaders in cancer research.
