Caroline

What’s better than a one-channel #Miniscope? 🥁 A TWO-CHANNEL Miniscope! Our new Miniscope2C is a dual-channel, open-source Miniscope that lets you record 2 fluorescent signals simultaneously in freely moving animals. Read the paper here: science.org/doi/10.1126/sc… (1/9)

Seriously, this message has to get out there. Without academic research we can’t produce the PhD and MS level scientists that drive scientific innovation in the private sector.

I have never been so glad I am at a public university with a salary backed by hard money.

Always nice to see more biosensors out there!

Sweet, can’t wait to set one of these up!

(1/7) Far-red dopamine sensor is coming! Excited to introduce our chemigenetic DA sensor, HaloDA1.0! #Dopamine #FarRedSensors, #GRAB biorxiv.org/content/10.110…

The Kruskal-Wallis test is a non-parametric method used to determine if there are statistically significant differences in the distributions of three or more independent groups based on ranks. Unlike ANOVA, it does not assume a normal distribution, making it versatile for analyzing non-normally distributed data sets. Advantages of Proper Use: ✔️ Suitable for ordinal data or non-normally distributed data sets. ✔️ Does not assume homogeneity of variance, offering more flexibility. ✔️ Can be used with small sample sizes, increasing its applicability in various research settings. Challenges If Not Handled Correctly: ❌ Interpretation can be complex, especially if the test is mistaken for a direct comparison of medians when specific conditions aren't met (e.g., independent samples, symmetric distributions). ❌ Less powerful than ANOVA when data is normally distributed, which can lead to less accurate results. ❌ May require post-hoc tests to pinpoint specific group differences, adding complexity to the analysis. How to Apply in Practice: 🔹 R: Use the kruskal.test() function from the base package to perform the Kruskal-Wallis test. 🔹 Python: Utilize the kruskal() function from the scipy.stats module for the analysis. Visualization Explanation: The visualization accompanying this post compares ANOVA and the Kruskal-Wallis test by ranks. This visualization is adapted from a Wikipedia source: en.wikipedia.org/wiki/Kruskal%E… For those interested in learning more, consider joining my online course on Statistical Methods in R, where we explore this topic and related methods in greater detail. Take a look here for more details: statisticsglobe.com/online-course-… #DataAnalytics #RStats #Rpackage #DataScientist

Just did my once a semester demonstration of how quickly I can get information by calling tech support, not texting or emailing them but actually having a conversation…I don’t think I convinced my students 🙃

Since my sister couldn’t wear her #Kamala4President shirts to vote, she dressed in sneakers, jeans, blouse, navy jacket and pearls…

Look what I found in the back of my closet, times have certainly changed since I was a grad student @ToxVcu

Don’t most programs provide a waiver if you ask?

Wow!!!

@CterminiPhD It usually takes me 3-4 years to work the last place out of my system.

Once you’ve been through a f*cked up mentoring relationship, it’s hard to act “normal” and go about your career. This job is particularly hard because you can’t ever really escape the triggers. They’re everywhere.

A few years ago I was in a position to do something unique in neuroscience. I had been working with the phenomenal @emilyjacobs on menopause and inspired by @laura_pritschet's menstrual study, and I was planning a pregnancy. What if we scanned my brain?? nature.com/articles/s4159…

Come be my colleague @SSIBsociety @ACNPorg @BlackInNeuro @SACNAS

🔥New Paper from the lab! Led by @mtaira_723 and our awesome team, we reveal the learning components signaled by dopamine release in the Nucleus Accumbens core (NAcC): jneurosci.org/content/44/35/…

Congrats to my friend and colleague Guosong Hong for his stunning and original discovery, published today in Science, on clearing tissues *in living animals* with a common food dye! The dye is tartrazine, used in Doritos! science.org/doi/10.1126/sc…

@stephjhuang @KESchoonover1 Damn that looks good, now I need to figure out a reason to do this stain..!

@KESchoonover1 Thank you! It's DiI :) Here's the method if you're interested: dx.doi.org/10.17504/proto…

An apical dendrite covered densely in dendritic spines from a cortical pyramidal neuron. #FluorescenceFriday

@mike_feigin Just one box?

Wow, this will be the “must read” paper of the week for my lab.