Carolin Sauer

118 posts

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Carolin Sauer

Carolin Sauer

@Carolinmsa

Postdoc researcher at EMBL-EBI @emblebi interested in cancer genomics and liquid biopsies 🧬👩🏻‍💻 Ballet and rowing enthusiast

Cambridge, England Katılım Kasım 2019
395 Takip Edilen303 Takipçiler
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Carolin Sauer
Carolin Sauer@Carolinmsa·
Thrilled to share our latest work now out in @naturemethods 🥳 We present SAVANA, a novel machine-learning based algorithm to detect somatic structural variants and copy number aberrations from long-read (@nanopore & @PacBio ) sequencing data with and without matched control!👇
Nature Methods@naturemethods

Introducing SAVANA, a tool to detect somatic structural variants and copy number aberrations from long-read sequencing data with high sensitivity and specificity. nature.com/articles/s4159…

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Sascha Feldmann
Sascha Feldmann@sascha_feldmann·
Postdoc Opening at EPFL - please share! I am hiring a post-doctoral fellow here in the Laboratory for Energy Materials at EPFL to work on the next generation of quantum light sources, with an earliest start date of January 2026 for up to 4 years. #quantum #light #energymaterials
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Carolin Sauer
Carolin Sauer@Carolinmsa·
This work paves the way for more reliable application of long-read sequencing in detecting SVs and SCNAs in cancer genomics!
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Carolin Sauer
Carolin Sauer@Carolinmsa·
Thrilled to share our latest work now out in @naturemethods 🥳 We present SAVANA, a novel machine-learning based algorithm to detect somatic structural variants and copy number aberrations from long-read (@nanopore & @PacBio ) sequencing data with and without matched control!👇
Nature Methods@naturemethods

Introducing SAVANA, a tool to detect somatic structural variants and copy number aberrations from long-read sequencing data with high sensitivity and specificity. nature.com/articles/s4159…

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Isidro Cortes-Ciriano
Isidro Cortes-Ciriano@isidrolauscher·
Thrilled to see #SAVANA out in @naturemethods🥳 SAVANA detects haplotype-resolved somatic SVs and copy number aberrations (SCNAs) and infers tumour purity & ploidy in clinical samples using long-read sequencing with or WITHOUT a matched germline control 👇nature.com/articles/s4159…
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Carolin Sauer
Carolin Sauer@Carolinmsa·
Join me at the International Symposium on Minimal Residual Cancer, where I am honoured to be speaking in Nice this May along leading experts from around the world to discuss the latest breakthroughs in liquid biopsy, circulating biomarkers, and precision oncology.✨ #ISMRC2025
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Isidro Cortes-Ciriano
Isidro Cortes-Ciriano@isidrolauscher·
Most excited to see our study presenting the mechanism driving ~50% of osteosarcomas (LTA #chromothripsis) out in @CellCellPress! How does the final version differ from the preprint? x.com/isidrolauscher… Buckle up!! -tons of new exciting results ahead! 👇👇
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Isidro Cortes-Ciriano@isidrolauscher

To close 2023, we present our work on #osteosarcoma genome and clonal evolution biorxiv.org/content/10.110… How does #osteosarcoma arise? What rearrangement mechanisms cause some of the most complex #chromothripsis events seen in human cancer? Does chromothripsis occur subclonally?👇

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Carolin Sauer
Carolin Sauer@Carolinmsa·
Very excited to see this out!💥 See thread below from @isidrolauscher if you are interested in calling somatic SVs and CNAs from long-read data! Huge congrats to @hbelrick on her very impressive PhD work, and big thank you for letting me join in with the copy number!
Isidro Cortes-Ciriano@isidrolauscher

Thrilled that #SAVANA is out🥳 biorxiv.org/content/10.110…, our method to analyse somatic SVs, allele-specific copy number aberrations (SCNAs), tumour purity & ploidy in clinical samples using #long-read sequencing @nanopore @PacBio! 😮 Comparisons of long/short reads & algorithms👇

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Isidro Cortes-Ciriano
Isidro Cortes-Ciriano@isidrolauscher·
Absolutely thrilled and honoured to be part of team #SAMBAI- we've just received a @CancerGrand award to study the multifactorial basis of cancer inequities! Proud to be part of an all-star team led by @MeliD32! Thanks @CR_UK & @theNCI for funding this important work! 🥳
EMBL-EBI@emblebi

Congratulations team SAMBAI on receiving a @CancerGrand award 👏 Researchers from @isidrolauscher’s group will contribute their expertise in genomics and computational biology to investigating cancer inequities in recent African heritage populations. ebi.ac.uk/about/news/ann…

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Vic Flores 🦊
Vic Flores 🦊@vflorelo·
Science takes you places Today I'm with friends and colleagues providing bioinformatics training in Panama City for several @pahowho countries
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Keşfet

@hbelrick @isidrolauscher @emblebi @naturemethods @nanopore @PacBio @je_valleinclan @sangerinstitute