CCavadas Lab

Ribeiro et al. show that rest-activity cycles, light re-entrainment and core body temperature regulation are impaired in Machado-Joseph disease, with the underlying mechanisms including disruptions in essential neuropeptides of the central clock. tinyurl.com/ykscwp9r

In our last paper we show that Circadian rhythms are disrupted in patients and preclinical models of Machado-Joseph disease #circadianrhythm #brain #MachadoJosephDisease doi.org/10.1093/brain/…

Overlooked histories in ageing research: Pioneering women at the foundation of our field onlinelibrary.wiley.com/doi/full/10.11…

@claudiacavadas @cnc_uc @AgingCell

Our results support the concept that the accumulation of senescent cells in the skin can exert #aging effects on other organs including the brain. onlinelibrary.wiley.com/doi/10.1111/ac… @CcavadasLab @PassosLab @cnc_uc

We are starting our symposium!!

We are organizing an advanced course for PhD students @cnc_uc “Advanced Insights into Primary Cilia: Molecular Functions, Disease Mechanisms, and Ageing” 7-8 November. Information about the speakers cnc.uc.pt/en/pdbeb/beb-a…

Our last paper published in Aging Cell!!! Transplantation of senescent cells in the skin accelerate ageing of other parts of the body, namely the brain!! doi.org/10.1111/acel.1… #aging #senescence #cognition #skin @cnc_uc @UnivdeCoimbra @Passoslab

We were at #EuropeanResearchersNight in Coimbra @cnc_uc @uc_iii @UnivdeCoimbra

@claudiacavadas was invited speaker at the The Sixteenth International Symposium on Neurobiology and Neuroendocrinology of #Aging will in Bregenz, Austria. qwd.at/aging/general.…)

We were at the 9th European Congress of Pharmacology #Ephar2024 @cnc_uc @UnivdeCoimbra

@claudiacavadas and Marisa Ferreira-Marques are here @EPHAR2024! We organized a symposium, presented a conference and a poster! We acknowledge Portuguese Society of Pharmacology for the support @spfarmacologia . #progeria #aging #longevity @cnc_uc @UnivdeCoimbra

Excellent conference by Olga Barca @cimususc about “Metabolic tempo: deciphering astrocyte clock entrainment via Insulin and AMPK signaling pathways” at our advanced course “Unveiling the Secret of Circadian Rhythm & Sleep in Health and Disease” @cnc_uc @UnivdeCoimbra @uc_iii

Now the neurologist João Durāes presenting the link between Neurodegenerative Disorders and circadian rhythm. @cnc_uc @befmuc

Joaquin Castilla presenting the open seminar about Fatal Familial Insomnia @cnc_uc @CICbioGUNE

Starting the second day of “Unveiling the Secrets of Circadian Rhythm & Sleep” advanced course organized by @CcavadasLab @cnc_uc @uc_iii @UnivdeCoimbra #sleep #circadianrhythm #aging

Isabel Santana presenting a long career in neurology and sharing the knowledge about prion diseases at our advanced course “ Unveiling the Secrets of Circadian Rhythm & Sleep” @cnc_uc #priondiseases

On 4th April, Claudia Cavadas, Associate Professor, Faculty of Pharmacy at University of Coimbra, will be talking about: Neuroendocrine strategies to tackle ageing #longevity #ageing #research @claudiacavadas More details about this and future webinars: bsra.org.uk/events/seminar…

Our lab is committed to better understand the pathology, new models, therapies for 3 rare diseases: ➡️ Hutchinson-Gilford Progeria Syndrome ➡️ Machado-Joseph Disease ➡️Familiar Fatal Insomnia @cnc_uc @UnivdeCoimbra #RareDiseaseDay #lightupforrare🟪🟦🟩