Pavan Chaggar

150 posts

Pavan Chaggar

Pavan Chaggar

@ChaggarPavan

Simultaneously a mathematician trying to be a neuroscientist and a neuroscientist trying to be a mathematician. PhD student at @oxunimaths

Oxford, England Katılım Ocak 2019
1.1K Takip Edilen237 Takipçiler
Pavan Chaggar
Pavan Chaggar@ChaggarPavan·
‼️ New preprint ‼️ How do amyloid-β (Aβ) and tau drive Alzheimer’s disease over time? We introduce a parsimonious, mechanism-based dynamical ATN (dATN) model to simulate longitudinal imaging biomarkers. A short thread 👇 Preprint: biorxiv.org/content/10.648…
BioFINDER@biofinder_study

New BioFINDER preprint! We formalise the Aβ–tau–neurodegeneration (ATN) framework into a mechanism-based model of AD, enabling us to simulate longitudinal imaging biomarkers and study how disease processes evolve and interact across the AD continuum. 🔗biorxiv.org/content/10.648…

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Brain
Brain@Brain1878·
The entorhinal cortex is the first region to develop tau pathology in AD. Using imaging data and a computational model, Alexandersen et al. show that brain-wide patterns of neuronal activity and amyloid burden drive early tau accumulation in this region. tinyurl.com/mrxb43bp
Brain tweet media
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Jake Vogel
Jake Vogel@_JakeVogel_·
I am hiring a research technician to help process and analyze multimodal neuroimaging data. Please RT!! * Great opportunity to gain research experience pre-PhD * Access to exciting data * Opportunities for independent projects Apply here: lu.varbi.com/en/what:job/jo…
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Linda Karlsson
Linda Karlsson@karlssonlinda1·
Very excited to share our new work on a machine learning-based prediction of tau pathology in AD! Many thanks to all study participants, my PhD supervisors @OskarHansson9, @_JakeVogel_, @NiklasMattson4, @astromkalle and all co-authors!
BioFINDER@biofinder_study

🚨New preprint out! medrxiv.org/cgi/content/sh… Tau-PET is the best prognostic AD biomarker, but is expensive and inaccessible. Can we use machine learning to get the same information from low-cost clinical variables? A thread on our new study led by PhD student @karlssonlinda1 👇

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