
Pavan Chaggar
150 posts

Pavan Chaggar
@ChaggarPavan
Simultaneously a mathematician trying to be a neuroscientist and a neuroscientist trying to be a mathematician. PhD student at @oxunimaths


‼️ New preprint ‼️ How do amyloid-β (Aβ) and tau drive Alzheimer’s disease over time? We introduce a parsimonious, mechanism-based dynamical ATN (dATN) model to simulate longitudinal imaging biomarkers. A short thread 👇 Preprint: biorxiv.org/content/10.648…

New BioFINDER preprint! We formalise the Aβ–tau–neurodegeneration (ATN) framework into a mechanism-based model of AD, enabling us to simulate longitudinal imaging biomarkers and study how disease processes evolve and interact across the AD continuum. 🔗biorxiv.org/content/10.648…





🚨New preprint out! medrxiv.org/cgi/content/sh… Tau-PET is the best prognostic AD biomarker, but is expensive and inaccessible. Can we use machine learning to get the same information from low-cost clinical variables? A thread on our new study led by PhD student @karlssonlinda1 👇