Chengsheng Ju

We are delighted to share that our paper, “Effect of statin treatment on the risk of cancer in patients with heart failure: A target trial emulation study” has been awarded with honourable mention of the Ronald D Mann award in Pharmacoepidemiology and Drug Safety!

🦴🩺 Fracture risk in type 2 diabetes is not just about obesity @JCSM_cachexia In a population-based cohort of 165,000+ people with T2D🇭🇰, we found that albuminuria is one of the strongest predictors of fractures, in both obese and non-obese patients. onlinelibrary.wiley.com/doi/10.1002/jc…

Initiating #metformin within 90 days of #COVID19 infection was associated with a reduced risk for #LongCOVID among adults with overweight or #obesity. @KennethKCMan @ChengshengJ @DrJanine_Mak @School_Pharmacy infectiousdiseaseadvisor.com/news/early-met…

Our study using data from the UK CPRD Aurum published in @CIDJournal shows that metformin use within 90 days of COVID-19 diagnosis reduces post-COVID risk in individuals with overweight/obesity. 📮Read more: doi.org/10.1093/cid/ci… @ChengshengJ @LiWeiUCL @KennethKCMan

And thanks to @OliviaKHop for picking up the certificate ☺️

onlinelibrary.wiley.com/doi/10.1002/pd… @LiWeiUCL @wallis_lau

We are delighted to share that our paper, “Effect of statin treatment on the risk of cancer in patients with heart failure: A target trial emulation study” has been awarded with honourable mention of the Ronald D Mann award in Pharmacoepidemiology and Drug Safety!

Fluoropyrimidine Chemotherapy and the Risk of Death and Cardiovascular Events in Patients With Gastrointestinal Cancer | JACC: CardioOncology jacc.org/doi/10.1016/j.…

jacc.org/doi/10.1016/j.… Thanks to Dr Abiodun, Prof @dr_manisty , and VICORI team!

Glad to be involved in this study, we applied target trial emulation techniques to high quality cardio-oncology registry data and answered an important question In patients with GI cancers, we found fluoropyrimidine ⬇️death risk, with small ⬆️cardiovascular event. @JACCJournals

In this study Vincent Ka Chun Yan and colleagues investigate the prescribing trends of indapamide and the long term comparative effectiveness of modified release versus immediate release indapamide. Read the full research article here: bit.ly/4bnRjc6

🔥 Hot off the press in Diabetes Research and Clinical Practice Our emulated trial of aspirin vs clopidogrel for 111,292 pts with ASCVD using 🇬🇧 primary care database showed similar risk of incident diabetes 🔵, CV events 🫀 & bleeding 🩸 doi.org/10.1016/j.diab…

A great collaboration between UCL, University of Dundee and HKU. Congratulations to @VincentKCYan @ChengshengJ Tom MacDonald, Isla Mackenzie, Rob Flynn, Bryan Williams, Yang Chen, Esther Chan, Jacob George & Li Wei for the publication of indapamide study bmjmedicine.bmj.com/content/4/1/e0…

Two papers. On the left, a non-randomized, non-crossover study showing that a one-off sauna exposure significantly decreased arterial stiffness, with implications on cardiovascular health. On the right, a randomized, crossover (more robust) study, showing no benefits on arterial stiffness or blood flow. Note the colossal difference in Altmetric score and media attention. The media favors sensational but flawed studies over rigorous ones, distorting public understanding. #science #media

Our paper using UK Biobank published in @JCSM_cachexia reveals a complex interplay between different lipid markers and skeletal health. I sincerely thank @fredho42 for his invaluable guidance and support during my exchange at @UofGSHW doi.org/10.1002/jcsm.1…

Our study using data from @uk_biobank revealed different associations of lipid traits and fracture risks published in @JCSM_cachexia : higher HDL-C a/w higher fracture risk, partially mediated through BMD; while Lp(a) not a/w fracture risk doi.org/10.1002/jcsm.1…

If you see an observational study where the drug works immediately for a disease that takes years to develop, throw the study out. Like this study claiming Ozempic reduces risks of Alzheimer’s in diabetics within 30 days of initiation. Junk science alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…

Wow. Clearly, causal EHR inference has a long way to go (nature.com/articles/s4159…). Why on earth would ceph/pen increase LoS but carbapenems decrease them? Does anyone peer review at Nat Med? I mean, this is literally just a dump of data that makes *no* sense

onlinelibrary.wiley.com/doi/10.1002/eh… Our new study shows a reduced use of pharmacological treatment for heart failure after a cancer diagnosis. Better cardio-oncology services are needed for patients living with both conditions. @LiWeiUCL @wallis_lau @PinkieChambers @dr_manisty

A fast bootstrap algorithm for causal inference with large data. Matthew Kosko, Lin Wang, Michele Santacatterina. Statistics in Medicine. onlinelibrary.wiley.com/doi/10.1002/si…