Crowley Group

This molecule lives on the brink of self-destruction cen.acs.org/articles/104/w…

Fundamental Chemistry Mechanisms ⚙️🦾#NeverStopLearningMedChem For higher resolution image and references please visit ➡️ cheminfographic.wordpress.com/2020/10/13/fun…

Higher education must rethink assessment practices in response to the growing integrity challenges posed by generative #AI, argue the authors of a new #SciencePolicyForum. scim.ag/49fG3Pc

Metal‐Free Active Template: A Straightforward Route to 4‐Aminopyridinium‐Based Rotaxane Molecular Shuttles - Stoyanov - Angewandte Chemie International Edition - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/an…

Thrilled to see our Feature Article published in @ChemComm! We highlight the interface between MIMs and porphyrinoids, aiming to give due credit to the people who shaped this field while showing some of our own contributions. pubs.rsc.org/en/content/art… @WCh_UWr

Today's daily morning seminar doi.org/10.1021/jacs.6…

Nominations are currently open for the sciPAD Denis Hogan Chemical Education Award. This award recognises the important contribution that an individual has made to chemistry education in New Zealand. nzic.org.nz/awards

Polystyrene pyrolysis using MOFs―#Polystyrene is one of the most common and abundant plastic materials, yet the chemical structure of this polymer hampers the implementation of chemical recycling. Now, Tatsumi, Uemura et al. report in @J_A_C_S a method for highly efficient thermal depolymerization of polystyrene mediated by nanoporous metal–organic frameworks (#MOFs). Nanoconfinement of polystyrene within a MOF enables the consolidation of complex degradation pathways in the nanochannels, restraining the formation of undesirable heavy-oil components composed of styrene oligomers and more selectively generating styrene monomers. Full article: pubs.acs.org/doi/abs/10.102…

‘If you’re using less water & less energy, those are obvious cost savings. ‘If you’re managing chemicals better & sharing them, you’re reducing waste and spending,’ says the HCUK chair-elect & head of chemistry @EdinburghUni Jason Love. @RoySocChem chemistryworld.com/news/handbook-…

#ICIQNews 🫙Prof. @PabloBallesterB's group has reported a molecular cage that promotes intermolecular azide–alkyne Huisgen cycloadditions, while showing that subtle changes in cavity size modulate the catalytic performance. Read more 🔗 iciq.org/new/cycloaddit… @gemma_aragay

Paper“Coordinative Guest Recognition Triggers Macroscale Deformation of Covalently Linked Metal-Organic Polyhedra Polymer Gels” pubs.acs.org/doi/10.1021/ja…

Excited to share our new paper in @angew_chem by @ArturoOro_chem!🧪 A nanographene-based van der Waals framework featuring permanent porosity, strong thermal stability, and aggregation-induce emission behavior!! Go check it out! 💥 doi.org/10.1002/anie.4…

Chemists typically make MOFs by reacting dissolved metal salts & organic linkers in a sealed container which can be energy-intensive. Now, researchers sped up the process with by electric fields. chemistryworld.com/news/electrify…

先日発表したMOPEGゲルをプレスリリースしました！ バスケ大好きな筆頭著者の立石さん@t_tateishi_ が素晴らしい図を作ってくれました。MOPは京都ハンナリーズ@kyotohannaryz の花浅葱、ゲストが仙台89ers @89ERS_Official のナイナーズイエローです。ぜひご一読ください！ icems.kyoto-u.ac.jp/news/11476/

分離しやすいPoly(2-pyridyl)phosphines試薬 pubs.acs.org/doi/10.1021/ac… 光延反応やAppel反応では、反応そのものよりもtriphenylphosphine oxide（TPPO）の除去がボトルネックになることが多いです。このアカウントでも、TPPOの結晶が取れたネタとか過去に書きましたが、有機合成化学者泣かせの副生成物ですね この論文は、2-pyridyl基を持つphosphineを使うことで、反応後のphosphine oxideをCuSO4水溶液洗浄または濾過で除去しやすくするという、非常にプロセス化学的な発想です。 特に、ヌクレオシドや複雑中間体のようにカラム精製を避けたい基質では有用性が高いと思います。反応性だけでなく、P-oxide purge、溶解性、抽出挙動、multigram scaleでの実用性まで見ています。 一方で、CuSO4 washを使う以上、金属残留、配位性官能基、金属感受性基質への影響は確認が必要かなと思います。したがって、単純なPPh3の完全代替というより、TPPO除去が問題になる基質で優先的に検討すべき、タイトルにもあるようにseparation-friendlyなphosphine reagentとして見るのが適切だと思います。

Conformationally Switchable Molecular Trefoil Knot Assembled From 2,6-Bis(1,2,3-triazol-4-yl)pyridine (btp) Building Blocks | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/ja…

Please do not submit a formal application yet. Shortlisted candidates will be contacted More about us: sites.google.com/view/labsoto/h… 3/3

First check the Chemistry grad admission requirements grad.usask.ca/programs/chemi… If eligible, send a motivation letter, transcripts, English score, and 2 reference contacts to miguel.soto@usask.ca by May 30 2/3

We’re recruiting two PhD students! 🧪 Join our group at the University of Saskatchewan 🇨🇦 starting Fall 2026 or Jan 2027. We work at the interface of supramolecular, inorganic, and materials chemistry. Synthesis and spectroscopy experience preferred ⚗️ Interested? 1/3

🎁HBT Jonathan Sessler (@JLsessler), who turns 70 today. He is most famous for his work on expanded #porphyrins, including texaphyrins. A native of Urbana, Illinois, he studied chemistry at the University of California, Berkeley (@UCBerkeley) and at Stanford University (@Stanford), where he received his PhD in 1982 for work on porphyrin chemistry with James P. Collman. After a postdoc with Jean-Marie Lehn in Strasbourg and a short stint in Iwao Tabushi’s group at the University of Kyoto (@KyotoU_News), Sessler began his independent career in 1984 at the University of Texas at Austin (@UTAustin), where he currently holds the Doherty–Welch Chair. His work on #porphyrinoids and #supramolecular chemistry, as well as on medicinal chemistry, has earned him many honors, including the Centenary Award of the RSC (@RoySocChem) and the ACS (@AmerChemSociety) Breslow Award in Biomimetic Chemistry. He is a member of the U.S. National Academy of Sciences (@theNASciences) and a foreign member of the Chinese Academy of Sciences (@CAS__Science). Sessler himself suffered from #cancer, and he used his expertise to develop biologically active anti-cancer compounds, which also led him to found several companies. Jonathan Sessler is a gifted teacher who has mentored over 250 PhD students and postdocs. He has served the scientific community in manifold ways, as editor of books and journals and as organizer of conferences. We wish him well for a healthy and fruitful future. #porphyrin #SupramolecularChemistry #MedicinalChemistry #BiomimeticChemistry #anticancer #AnticancerCompounds