Curt D. Sigmund, PhD

Role of the Renin-Angiotensin System in Blood Pressure Regulation in Smooth Muscle-Specific Cullin-3 Deficient Mice | Hypertension ahajournals.org/doi/full/10.11…

LET'S GOOOOOOOOO

@CurtSigmund, Grobe, Nakagawa lab dinner at Hypertension Scientific Sessions in Baltimore.

No pressure—but if the renal baroreceptor machinery piques your curiosity... @curtsigmund & team @MedicalCollege reveal mice lacking CUL3 in vascular smooth muscle cells exhibit robust hypertension with paradoxically unaltered renin expression and decreased integrin β1 expression. See the full report: insight.jci.org/articles/view/…

Cullin-3 regulates the renal baroreceptor machinery that controls renin gene expression

One of my favorite moments from this weekend.

Sigmund Laboratory 2025

@CurtSigmund @JLGrobe @NakagawaPablo @akwitek annual holiday lunch.

There is renin in the brain!!!!!! Great job team from @MCWPhysiology. Definitive Evidence for the Identification and Function of Renin-Expressing Cholinergic Neurons in the Nucleus Ambiguus | Hypertension ahajournals.org/doi/abs/10.116…

@VerizonSupport - cell data international stopped several hours ago. Was working fine for almost 2 weeks and stopped on 2 phones with you top international plans at 4 PM local time in Italy.

Sigmund, Grobe, Nakagawa lab dinner at AHA Hypertension Scientific Sessions 2024 in Chicago. @MCWPhysiology @JLGrobe @NakagawaPablo

@CouncilonHTN Impressive.

#Hypertension24 is 1 week away. Hope to see you! Lots of exciting programming lined up for you! Tell us why you attend.

@CFWenceslau @JunieWarrington @brandimwynne @CamGMcCarthy @Carmendemigue12 @annetkiraboc1 @AusRob_PhD If you setup an exhibit, you get a waste basket, pretty exciting……look for it!

My favorite part of attending #Hypertension2024 is seeing the cutting-edge research and reconnecting with friends! What about you @JunieWarrington @brandimwynne @CamGMcCarthy @Carmendemigue12 @annetkiraboc1 and @AusRob_PhD?

Oh no! The giant score board is off. @Brewers

@CterminiPhD If this is to be a long term collaboration, then a collaborative "conduit" such as a co-mentored graduate student or postdoc to work across labs. I have done this many times and everyone benefits.

It takes skill to become a good collaborator and if you didn't train in collaborative labs, it can be challenging to build this skill set when you become a PI. I'm still very new to this! What are your top tips for new PIs learning how to collaborate with other labs? #NewPI

Time for @MayorMKE to step in and save July 3 fireworks. Be the hero…..Our increased tax dollars at work. #MKEFireworks.

Congratulations to @MCWPhysiology student Alisha Ziegler and mentor @JLGrobe on being hooded at the @mcwgradschool hooding ceremony yesterday.

Congratulations to @nmathieu29 on publication of her thesis research. Deletion of β-Arrestin 2 From the Subfornical Organ and Other Periventricular Nuclei in the Brain Alters Fluid Homeostasis and Blood Pressure. ahajournals.org/doi/abs/10.116… @MCWPhysiology @CurtSigmund

Congratulations to @nmathieu29 Natalia Mathieu, a graduating @MCWPhysiology PhD student for winning the best predoc presentation of the Water and Electrolyte Section at #APS2024.

Group dinner at #APS2024 @MCWPhysiology @CurtSigmund