Digital Health and Patient Safety Platform

Impacts of biomedical hashtag-based Twitter campaign: #DHPSP utilization for promotion of open innovation in digital health, patient safety, and personalized medicine digitalpatientsafety.com/impacts-of-bio… #DigitalHealth #PatientSafety #PersonalizedMedicine #HospitalsTalkToLovedOnes

Not all impactful science is obvious at the start. Some begins as risky, collaborative experiments. This is one of those stories 👇 citationclassics.com/stories/from-c… #INPST

🏆 We have a winner! Announcing the Highly Cited Paper Award 2025 in Exploration of Digital Health Technology (EDHT). explorationpub.com/Journals/edht/… 👏 Congratulations to the authors! #ExplorDHT #DigitalHealth #OpenAccess #HighlyCited

🚨 Just 10% more ultra-processed food in your diet? ▶️ Your risk of dying goes up by 10%. ▶️ New meta-analysis of over 1 million people says it’s time to rethink what’s on your plate. 🔗inpst.net/ultra-processe… 🌐 #INPST #Health #Nutrition #Longevity

#Master Class at @UnivPoliMarche for Marie Sklodowska-Curie Postodoctoral Fellowships Call is open, apply before April 10 #DHPSP #INPST @_atanas_

American College of Sports Medicine Position Stand. Resistance Training Prescription for Muscle Function, Hypertrophy, and Physical Performance in Healthy Adults: An Overview of Reviews ▶️ Healthy adults should perform progressive RT, with variable prescription consistent with our findings, to improve muscle function, size, and physical performance. Muscle strength, hypertrophy, power, and certain components of physical function can be enhanced by manipulating the RT variables highlighted. journals.lww.com/acsm-msse/full… @CelestinoGutirr @DelRealMartin2 @drfherediaz @HealthyFellow @run_it_back_exe

Olfactory cleft biopsy analysis of Alzheimer’s disease pathobiology across disease stages ▶️ A simple sample taken from the top of the nose to collect nerve and immune cells can detect early biological changes related to Alzheimer's, even before thinking and memory problems appear. ▶️ The nasal swab allowed for the detection of early changes in nerve and immune cells. This includes individuals who showed signs of Alzheimer's disease in the laboratory but were not yet experiencing symptoms. ▶️ A combined genetic scoring of nasal tissue correctly differentiated early-stage & clinical Alzheimer's disease from healthy controls in approximately 81% of cases. nature.com/articles/s4146… @CelestinoGutirr @DelRealMartin2 @drfherediaz @HealthyFellow @LoriShemek @DrGrimaldesJ @DrRPalmquist

Chlorogenic acid and gallic acid synergistically reduce hyperglycemia and hyperlipidemia in diabetic BALB/c mice ▶️ The combination of CGA & GA exerts a synergistic effect that significantly reduces hyperglycemia and hyperlipidemia in diabetic BALB/c mice, showing greater efficacy than when administered separately. Sources of CGA: green tea, yerba mate, cacao, fruits (apple, pear, blueberry, strawberry). Sources of GA: Grapes and red wine, pomegranates and berries, nuts, mangoe and bananas. nature.com/articles/s4159… @drfherediaz @drfherediaz @_atanas_ @CelestinoGutirr @DrGrimaldesJ

🧵 1/6 🔬 Science-backed, not hype. These 6 compound types are changing the game in nutrition & health. 👉 linkedin.com/feed/update/ur… 🌐 #INPST #FunctionalFoods #HealthScience @DrSharadVats1 @rafael52987 @Dra_TeraizaMesa @HealthyFellow @ShraboniGhosal @CarbonEngineer4

Dermatological conditions for which sunbathing can be beneficial ▶️ Some dermatological conditions can improve their symptoms or progression thanks to responsible sun exposure: Psoriasis Atopic dermatitis Acne Vitiligo lavanguardia.com/vida/salud/202… @_atanas_ @CelestinoGutirr @DelRealMartin2 @drfherediaz @DrGrimaldesJ @guani_vic

Total and different types of olive oil consumption, gut microbiota, & cognitive function changes in older adults ▶️ Higher consumption of virgin olive oil was associated w/cognitive preservation, possibly mediated by favorable alterations in gut microbiota composition. link.springer.com/article/10.118… @_atanas_ @tatiann69922625 @drfherediaz @HealthyFellow @CelestinoGutirr @DrGrimaldesJ

Kombucha as a Bioactive Functional Beverage: Current Evidence, Production Challenges, and Future Perspectives Bioactivities that contribute to human health: Antioxidant Anticancer Antimicrobial Anti-inflammatory Hepatoprotective Antidiabetic mdpi.com/1422-0067/27/6…

@pushmeet @GoogleDeepMind The real breakthrough isn’t prediction—it’s democratization of knowledge

Natural products in drug discovery: advances and opportunities nature.com/articles/s4157… | @_atanas_

Resveratrol Mitigates Age-Associated Cognitive Decline via Inhibition of cGAS-STING-Mediated Microglial Senescence ▶️ Resveratrol mitigated brain aging and microglial senescence by suppressing cGAS-STING pathway activation and STING signal transduction. ✅️ These results not only support the central role of the cGAS-STING axis in microglial senescence and age-related brain dysfunction but also highlight a novel anti-aging mechanism of resveratrol that may be exploited for future therapeutic development. mdpi.com/2073-4409/15/6… @DrRPalmquist @CelestinoGutirr @DrGrimaldesJ @drfherediaz @_atanas_

Presence of neutrophil extracellular traps (NETs) in different types of human urinary tract infections (UTI). A pilot study ▶️ Cystitis is the most common UTI in humans. This infection can ascend the urinary tract, spreading to the renal pelvis and potentially causing serious conditions such as pyelonephritis or urosepsis. ▶️ Human UTIs are primarily of bacterial origin, with E. coli being the most common urogenital pathogen. ▶️ A key defense mechanism of the innate immune system involves the formation of NETs that can trap and eliminate microbial agents. ▶️ Activated polymorphonuclear neutrophils (PMNs) release NETs, composed of a reticular DNA core, along w/nuclear histones, granular peptides, & enzymes. ▶️ Elevated levels of NETs, ​​exDNA, and related proteins, such as LL37 and MPO, were detected in urine samples from patients with UTIs & were associated w/leukocyturia. ▶️ Drugs such as furosemide, which affect the kidney's electrolyte balance & reduce NET formation, can exacerbate pyelonephritis. ▶️ The formation of the NETosis phenomenon is linked to the exacerbation of UTIs. ▶️ The presence of NETs in human urine confirms their role in the pathogenesis of urinary tract infections (UTIs). ▶️ Understanding these complex mechanisms could contribute to the development of targeted therapeutic strategies for patients with UTIs, although the polymicrobial nature of many complicated or recurrent UTIs poses a challenge. doi.org/10.3389/fimmu.… @HealthyFellow @tatiann69922625 Live-cell fluorescence microscopic (LCFM) analysis of human urine samples for the detection of bacterial colonization, leukocyturia, cellular activity and NET release

@_atanas_ Yes.

@_atanas_ Evidence-based communication is vital. Clear science helps combat the pseudoscience harming patient communities every day.

@_atanas_ Promising for gut-brain axis research in conditions like ME/CFS. We need tools that reveal function, not just presence.

🔎 Chemical biology tools reveal which microbes are truly working behind the scenes 🔗 inpst.net/innovative-che… 🌐 #INPST #Biotech #CRBIOTECH

Association between menopause-related symptoms & muscle mass index among perimenopausal & postmenopausal women and the mediating role of estrogen levels ✅️ Lower muscle mass is associated w/severe menopausal symptoms, partially mediated by estrogen. ✅️ Maintaining muscle mass may alleviate symptoms, highlighting the importance of resistance training & hormone regulation in perimenopausal women. frontiersin.org/journals/endoc… @DHPSP @_atanas_ @drfherediaz