David Guttery

Pleased to share that our paper on Plasmodium NEK4 is now published in @NatureComms. NEK4 act as a key regulator coupling meiotic entry with cytoskeletal morphogenesis in malaria parasites. Huge thanks to @RitaTewari, @David_Guttery & all our co-authors. nature.com/articles/s4146…

We are looking to recruit two highly enthusiastic and motivated research fellow to work on Plasmodium cell division (unusual mitosis and meiosis). Funded by @ERC_Research ;@BBSRC. please apply below . jobs.nottingham.ac.uk/MED459826 jobs.nottingham.ac.uk/MED482026

Two posts open to work on Plasmodium cell division (unusual mitosis in male cells and meiosis in ookinete). Funded by @ERC_Research and @BBSRC Research Associate/Fellow in Plasmodium Meiosis: lnkd.in/dP3Zh-cs Research Associate/Fellow: lnkd.in/dda_yq3s.

@RyujiYanase All the very best Ryuji 👍

I have officially started my new position as a Senior Research Scientist at the National Institute of Infectious Diseases (NIID) 🇯🇵. My group will focus on the cell/molecular biology of parasitic Excavata & amoebae (incl. Trypanosoma, Naegleria, Acanthamoeba, & more) (1/3)

Chromosomes stuck behind the spindle are ticking time bombs for aneuploidy. We uncovered a mechanical rescue mechanism where microtubule pivoting repositions these high-risk chromosomes! Out last week in @NatureComms, here's a thread 🧵 shorturl.at/OD89x

Happy to share our work on Aurora kinase 1 (ARK1) that drives atypical mitosis and proliferation of the malaria parasite @RyujiYanase @EelcoTromer @Zeeshan_MF @PushkarTweeter @David_Guttery @KarineLeRoch1 nature.com/articles/s4146…

@RyujiYanase Really good work Ryuji! Lots more to come 😀

Our new preprint describes Plasmodium NEK4 as a key regulator coupling meiotic initiation and morphogenesis—a critical step for malaria transmission. This involves MTOC-driven nuclear movement strikingly analogous to "horsetail" movement in fission yeast. biorxiv.org/content/10.110…

Apicortin in malaria parasite are part of conoid like apical pole in invasive stages present only in female mosquitoes. Many thanks @Zeeshan_MF Carolyn Moores Tony Holder.

Plasmodium ARK1 regulates spindle formation during atypical mitosis and forms a divergent chromosomal passenger complex biorxiv.org/content/10.110… #biorxiv_micrbio

Pleased to share our new preprint: "Plasmodium ARK1 regulates spindle formation during atypical mitosis and forms a divergent chromosomal passenger complex". A huge thanks to all our collaborators. @RitaTewari @EelcoTromer @David_Guttery @Zeeshan_MF biorxiv.org/content/10.110…

This World Mosquito Day, let’s remember: to halt malaria transmission, we must uncover the fundamental secrets of parasite cell division during its critical stages inside the mosquito. This is what drives the research here in Nottingham. @RitaTewari @RyujiYanase @akki_mish

Our #CryoET story on how a top antimalarial drug candidate perturbs the native malarial translation machinery is out @NatureSMB🥳rdcu.be/eBbrH Massive team effort led by @leonie_anton @mehsehret @Wenjing_Cheng_ in collaboration with @DziekanJerzy @CowmanAlan #teamtomo

How do parasites strategically organise their genomes to influence gene expression? If you’re curious, check our latest review in @TrendsParasitol! A great team effort with @singh_parul Maureen Cabahug, Leon Walther & and the amazing Jessica Bryant!! sciencedirect.com/science/articl…

Friday Monster drinking session resulting in “Contemporary art”. @David_Guttery @akki_mish @RyujiYanase

We are looking for motivated and enthusiastic research fellow to join our group to investigate on #ERC project on cell division in malaria parasite. Job Vacancy at the University of Nottingham: Research Associate/Fellow (fixed term) jobs.nottingham.ac.uk/MED145725.

Looking for a fully-funded D. Phil. / Ph.D. studentship in structural biology and vaccinology? Come to join our team. Fully and generously funded by a donation from the Kyner-Field family with full fees at overseas level. Join us?? bioch.ox.ac.uk/studentships

In @eLife: A novel SUN1-ALLAN complex coordinates segregation of the bipartite MTOC across the nuclear envelope during rapid closed mitosis in Plasmodium berghei doi.org/10.7554/eLife.…. Out today. If you are at @biomalpar then happy to show the poster on it.

It was a great pleasure to have ⁦@ChristophidesG⁩ at Nottingham telling us all about gene drive in transmission zero for controlling malaria transmission.⁦@David_Guttery⁩ ⁦@RyujiYanase⁩