DeRing

Sleep Loss Weakens Brain’s Ability to Block Unwanted Memories Sleep deprivation impairs the brain's ability to suppress unwanted memories, a function critical for maintaining mental health. In a study, well-rested participants could engage the prefrontal cortex to block intrusive thoughts, while sleep-deprived individuals struggled. The hippocampus, responsible for memory retrieval, showed reduced activity during suppression in rested participants but remained overactive in those deprived of sleep. REM sleep played a key role in restoring the brain's memory suppression mechanisms. These findings help explain why poor sleep is linked to conditions like anxiety, depression, and PTSD. Researchers suggest targeting sleep improvement as a potential therapy for enhancing mental resilience.

State of DePIN 2024 🧵

[ DePIN ] - [ AI ] ❌ [ DePIN 🫂 AI ] ✅

2025: The Year of DePIN

If DePIN existed in 2009–Uber, AirBNB, and DoorDash would have scaled as DePINs. Any new infra network vertical with no incumbent favors DePIN due to its speed advantages over a Web2 model. The prize is network effects and speed of network expansion determines the winner. Caveat is demand side must likely be centralized initially to handle regulations, develop a strong UX, and conduct marketing.