Matt Demmings

6/ It was privilege to lead the work and a huge thanks to all the amazing lab members who made this possible. @WesternU @SchulichMedDent #NeuroTwitter #Parkinsons #ISR #mTOR #ATF4 #Neurodegeneration

5/ This work helps explain why persistent stress signaling is so toxic to neurons—and why the ISR, while protective in the short term, can become destructive over time. Implications go far beyond PD—mTOR, ISR, and ATF4 are key players in many neurodegenerative diseases.

The peer review process can be long, so we are delighted to share our work at: biorxiv.org/content/10.110… "ATF4 activates a transcriptional program that chronically suppresses mTOR activity promoting neurodegeneration in Parkinson’s disease models" 🧵👇

My @ISN_society friends and I got together and discussed neuron-glia interactions. This great team effort was born back in 2019 at the Advanced School!! @JNeurochem onlinelibrary.wiley.com/doi/10.1111/jn…

Had an awesome time in Boston discussing science and potential research projects! (No, I did not wear shorts and a hat to my meetings)

Sunrise from Shawshank

@LabFerguson @CIHR_IRSC @Krm_Ib @uOttawaMed @OttawaCmm @uOttawa @uOttawaBMRI Congrats! I’ll never forget you hitting a golf ball into the woods and immediately saying “oh well, still have two CIHR grants”

Elated to have our Huntington @CIHR_IRSC grant renewed. The lab is back to three CIHR grants and now reinvigorated post pandemic. Congratulations to @Krm_Ib for making this wonderful day possible for the lab. @uOttawaMed @OttawaCmm @uOttawa @uOttawaBMRI

@Dr_FelixChan @ISN_society @BorgesLab_UQ @JNeurochem Retweet!

Happy New Year! In reflecting on my 2022, I realized one of the most fulfilling moment was meeting the incredible @BorgesLab_UQ at the @ISN_society @JNeurochem Flagship School. Karin is just an awesome human being and my personal science hero! Here’s to more science in 2023!

@VulnerableBrain But the @CTVNews guy told us all about the “neutrons” last night on the news 😂😂

Really important (and insightful) thread. 27% reduction on that clinical scale does not equate with absolute value of protection (2.5%)

An emotional ovation for Borje Salming ahead of tonight’s game. 💙

@McGovern_AJ @ibroSecretariat @InstitutoCajal @BioSci_UL @UL_Research @sci_engUL Yes lad!! Congrats

Absolutely elated to share that I was awarded an @ibroSecretariat exchange fellowship award to continue my PhD studies in the @InstitutoCajal in Madrid for this semester! @BioSci_UL @UL_Research @sci_engUL

@ISN_society @CarsanaEmma @JNeurochem @CEAParisSaclay It was such a good talk!

The quest to observe many cellular targets simultaneously in live cells continues! Here is a timelapse of 6 organelles in human cancer cells.

@WesternU’s very own @maximoprado joining us in Germany via Zoom talking about best practices for publishing in @JNeurochem at the @ISN_society school 🇨🇦 🇩🇪

@ruisilrodrigues @AcademicChatter Ride as in getting stuck upside down on a roller coaster?

@AcademicChatter Enjoy the ride 😉

What's your single best tip for new starting PhD students?

On the @DB_Bahn today to travel to the @ISN_society Flagship School 🚂🇩🇪🧠 This whole Science journey can be pretty awesome at times 🍺✌🏻