Dimpy Kalia

We are delighted to share that a research article titled “Rapid and High-Yielding Disulfide Bioconjugation at Any Desired Site in Proteins” from the research group of Dr. Dimpy Kalia, Department of Chemistry has been published in the prestigious 𝙅𝙤𝙪𝙧𝙣𝙖𝙡 𝙤𝙛 𝙩𝙝𝙚 𝘼𝙢𝙚𝙧𝙞𝙘𝙖𝙣 𝘾𝙝𝙚𝙢𝙞𝙘𝙖𝙡 𝙎𝙤𝙘𝙞𝙚𝙩𝙮 (JACS). The article describes the development of 𝗦𝘁𝗮𝗽𝗹𝗲𝗔𝗹𝗱 technology, a robust platform enabling stable, rapid, and quantitative disulfide bioconjugation of solvent-exposed cystine disulfides in proteins under physiological conditions. When combined with LAP tag technology (LAP-StapleAld), this chemistry becomes location-agnostic, allowing precise installation of lipoyl disulfide linkages at any desired site on a protein—opening new possibilities in chemical biology and protein engineering. IISER Bhopal congratulates Dr. Dimpy Kalia and her research team on this outstanding achievement and wishes them continued excellence and many more high-impact scientific contributions. 🔗 Access the article via this link: pubs.acs.org/doi/full/10.10… @EduMinOfIndia @IndiaDST @DBTIndia @ANRFIndia @dasgobardhan @Dimpy_IISERB @chm_iiserb @J_A_C_S #IISERBhopal #ResearchExcellence #JACS #ScientificAchievement #ProteinBioconjugation #ChemistryResearch

@J_A_C_S @iiserbhopal @ANRFIndia @shivkuma_k @chm_iiserb

Our latest paper is out in @J_A_C_S on disulfide bioconjugation on proteins (my first as a mother). This one is for you, little Timisa! Thanks @iiserbhopal @chem_iiserb @ANRFIndia @shivkuma_k for funding. #womeninstem #chemicalbiology #organicchemistry

We are delighted to share that Dr. Dimpy Kalia, from the Department of Chemistry, has been awarded the Thieme Chemistry Journals Award 2025. This prestigious recognition celebrates her significant contributions to the field of chemical research. Adding to this achievement, Dr. Kalia’s lab has been awarded the MIT–IIT Kanpur Seed Fund Grant enabling her lab to join hands with Prof. Elizabeth M. Nolan’s group at MIT to investigate the unchartered pathways of bacterial signaling. Congratulations to Dr. Kalia and her team on these outstanding accomplishments! @iiserbhopal @dasgobardhan @EduMinOfIndia @IndiaDST @DBTIndia @serbonline @Dimpy_IISERB

My lab has been awarded the MIT-IIT Kanpur Seed Fund grant @MISTIatMIT with Prof. Elizabeth Nolan's lab at @ChemistryMIT which will fund visits of personnel between the two labs enabling us to join forces to study bacterial signaling mechanisms using chemical biology approaches.

Chemistry PhD interviews at IISER Bhopal have been announced. This time, there are several available positions in my group (sites.google.com/iiserb.ac.in/d…) to pursue projects in synthetic organic chemistry, protein bioconjugation and chemical biology of bacterial signaling mechanisms.

Humbled to be chosen as a Thieme Chemistry Journals Awardee 2025. Thanks to @thiemechemistry for the honour, and to @iiserbhopal , @chm_iiserb and @ANRFIndia for supporting my lab's research. thieme.de/en/thieme-chem…

Huge thanks to Dr. Ajay Kumar Srivastava, Dr. Kishor Mohanan, Dr. Namrata Rastogi, Dr. Anil Kumar K.S. and others for hosting such a great meeting.@chm_iiserb @iiserbhopal

Honored to present at my alma mater @CSIR_CDRI and meet the person who shaped my career, my PhD advisor Dr. Dinesh Dikshit, and @batysan, Dr. Radha Rangarajan, Dr. Madhu Dikshit, @GautamPanda7, Dr. Amit Misra, Dr. Saman Habib, Dr. Koneni Sashidhara and others

Back from an extremely enriching US visit. Presented talks at the Bioorganic Gordon Conference, @TuftsUniversity , and @ChemistryMIT. Huge thanks to GRC organizers @hargrovelab and @jbaryza, and @MattDShoulders and @Yu_Shan_Lin for hosting me at MIT and Tufts respectively.

@DDasLab @NatureComms @serbonline @iiserkol Congratulations, Dibyendu! Nice work!

Just online @NatureComms cationic peptide nanotubes can bind weak hydride transfer agents to facilitate efficient reduction of esters in water! Grateful to Swarnajayanti Grant, @serbonline , CSIR & @iiserkol rdcu.be/dJbwI #systemschem #enzymemimics

@iiserbhopal @EduMinOfIndia @IndiaDST @serbonline @chemeng_iiserb @INYAS_INSA @paramitadas_drg Congratulations, Paramita!

Congratulations Dr. Paramita Das, Asst. Professor, Dept. of Chemical Engineering, IISER Bhopal on been inducted as a member of the Indian National Young Academy of Science (INYAS) in 2024. @EduMinOfIndia @IndiaDST @serbonline @chemeng_iiserb @INYAS_INSA

@MonikaRaj_lab @TheRajLab1 Congratulations, Monika!👍

Super excited to share the news that I have been promoted to Full Professor of Chemistry. Nine years of roller coaster journey from Assistant Professor to Full Professor. Thanks to all the past and current members of @TheRajLab1 for making it possible.

@ruchianand1975 @India_Alliance @serbonline @IndiaDST @DBTIndia @iitbombay Congratulations, Ruchi!

Honoured to be recipient of the Sun Pharma Science Foundation Research Fellowship. My heartfelt thanks to the foundation and congratulations to my fellow awardees. I thank @India_Alliance @serbonline @IndiaDST @DBTIndia @iitbombay for their continuous support

Really humbled to receive praise from the great @kiranshaw for our lab's BHoPAL technology! Thank you very much ma'am for your kind words. Looking forward to employing BHoPAL for both pharmaceutical and basic research.@iiserbhopal @chm_iiserb @IndiaDST @serbonline #WomenInSTEM

@iiserbhopal ianslive.in/iiser-bhopals-…, bnnbreaking.com/breaking-news/…

Selected links of the media coverage of our recent paper. Thanks @iiserbhopal @chem_iiserb for the tremendous support at every stage from the start of the project 6 years ago right until the press release health.economictimes.indiatimes.com/news/pharma/ph…, daijiworld.com/news/newsDispl…, newsuw.com/news/technolog…

@iiserbhopal @chm_iiserb

@NatureComms @iiserbhopal @chm_iiserb @serbonline @IndiaDST Thanks a lot everyone for your comments and reactions. I truly appreicate your support and encouragement!

Unveiling our BHoPAL technology for quantitative location-agnostic site-specific protein labelling @NatureComms (nature.com/articles/s4146…) @iiserbhopal @chm_iiserb @serbonline @IndiaDST #organicchemistry #proteinbioconjugation #chemicalbiology #SERBPOWER #WomenInSTEM

Celebrating International Day of Women and Girls in Science !!! On this day, we are honoring the intellect, tenacity, and steadfast strength of women in science. #InternationalDayForWomenInScience #ACS_Students_chapter #AmericanChemicalSociety