Isabel González Mariscal

✨Exciting to see clinical efficacy of peripheral #CB1R antagonism with #monlunabant. It will expand armamentarium for #obesity with a different mechanism than incretins (#GLP1 #GIP) ⚡️Similar efficacies in all tested oral doses encourage testing lower doses to optimize safety.

🔎What’s shaping the future of #diabetes #research? In this episode, Prof. Hindrik Mulder, Editor-in-Chief of @DiabetologiaJnl , discusses AI, health disparities, beta-cell breakthroughs, and more. Listen now🎧👉 easd.org/media-centre/p…

"Don't be afraid!" Randy Schekman says that the most successful scientists are willing to take risks. He uses 2024 chemistry laureate David Baker as an example of how embracing risk can lead to significant rewards. Before Baker transitioned to researching structural biology he studied systems of protein transport in yeast. Prior to that, he earned a bachelor's degree in philosophy and social science, demonstrating that no career change is too drastic. Schekman was awarded the 2013 medicine prize jointly with James Rothman and Thomas Südhof for their discoveries of machinery regulating vesicle traffic, a major transport system in our cells.

¿ Es posible modular los síntomas depresivos en personas desnutridas en hemodiálisis con psicobióticos y suplementos nutricionales orales? Descúbrelo en mdpi.com/3178216 @Nutrients_MDPI @endo_nutri @InfoUMA @HRegionalMalaga @sociedadSEEN

Buscamos personas con diabetes tipo 1 que deseen mejorar su bienestar emocional mediante el aprendizaje de estrategias afrontamiento del estrés. Ponte en contacto con nosotros en myremedy@uma.es. Se puede hacer íntegramente "online" @sociedadSEEN @endo_nutri @InfoUMA

Adverse #skeletal effects of some forms of #bariatric surgery are well documented, but the effects of incretin-based therapies, such as #GLP-1 receptor agonists, remain to be fully established thelancet.com/journals/landi… #weightloss #obesity #osteoporosis #fractures #BMD #BoneHealth

Xenotransplantation of a Porcine Kidney for End-Stage Kidney Disease | New England Journal of Medicine nejm.org/doi/full/10.10…

Exercise again in the spotlight: can really any drug amalgamate all the benefits of exercise?

@IDiBE_UMH @lmarroqui @rsdossantos13 @UniversidadMH @GVAfisabio @umhsapiens Congratulations!!! Great science in #diabetes coming from top researchers and even better human beings. Bringing excellence to @ciberdem and the Fundamental Research in Diabetes Study Group from @SEDiabetes

📢 ¡¡ GRAN NOTICIA !! Los investigadores 👩‍🔬@lmarroqui y🧑‍🔬@rsdossantos13 recibirán financiación del EFSD/Lilly European Diabetes Research Programme para estudiar la inhibición de la vía de interferón-alfa como posible terapia preventiva en #DiabetesTipo1 🩸

@sevillegauthier @a_bartolome @IIBmCSICUAM @CSIC @UAM_Madrid @ciberdem Same!!

@a_bartolome @IIBmCSICUAM @CSIC @UAM_Madrid @ciberdem Hi, I would certainly be interested to e-attend... It's there an online link? Thanks

🚨 In two weeks, @IIBmCSICUAM will host a Symposium on the Pancreatic Islet, featuring local researchers sharing their latest findings. 📍 Madrid | 🗓️ Wednesday, 19th No registration needed—just drop by! Definitive program avaliable Don't miss it! 🔬 #DiabetesResearch

Divide to conquer! New manuscript from @InsermU1190 and @stefano_romeo76 in @NatureMedicine, towards precision medicine by data-driven cluster analysis in #MASH . Bravo @RaverdyVioleta @francois_pattou!

@tony_jourdan1 I understand....

@DoctorIGM Still trying to understand the process. But i can no longer stand the racist, BS and fake news i receive everyday here...

Did the thing. Not sure i'll be more active there than here though 😅

Excited to share our new study in Diabetes! We reveal how type 2 #diabetes drives #epigenetic changes in PNLIPRP1, triggering a cascade in the exocrine pancreas toward precancerous states! #T2D #PancreaticCancer @philippefroguel @ImperialMDR @PasteurLille diabetesjournals.org/diabetes/artic…

Wang et al. report the preliminary analysis of a first-in-human phase I clinical trial assessing the feasibility of autologous transplantation of chemically induced pluripotent stem-cell-derived islets to an abdominal site for #type1diabetes treatment. cell.com/cell/abstract/…

Are we forgetting the impact of #sedentarism on #health? Importance of #exercise at the microtissular level, also for #islets !

Back to my AMPK roots and a fantastic collaboration with ⁦@caguayo⁩ and ⁦@carapetop⁩. Exercise activates AMPK in mouse and human pancreatic islets to decrease senescence | Nature Metab. ⁦@CRCHUM⁩ ⁦@HIRN_CC⁩ ⁦@cusm_muhc⁩ nature.com/articles/s4225…

So honored! New times for old GPCRs

Up front & free to read in our Sept issue #editorspicks: Pharmaceutical targeting of the cannabinoid type 1 receptor impacts the crosstalk between immune cells and islets to reduce insulitis in humans tinyurl.com/35raxcve