Khalid Dousa

Because selecting a mentor can be one of life's most important decisions. Thank you Robert A. Bonomo @IDWeek2019

⭐️ Thinking about #GI fellowship as an #IMG? Don’t let visas be the black box ⬛️ ❗️ We’re breaking it ALL down—J-1, waivers, H-1B, NIW—with an immigration lawyer ⚖️ + real physician experiences 🩺 @ASGEendoscopy #MedEd asge.zoom.us/webinar/regist…

Bad to the bone: Researchers from @CWRUSOM highlight the complexity of managing invasive C. auris osteomyelitis. Dual #antifungal combination therapy can enhance efficacy - potentially preventing the development of resistance. #ASMCaseReports doi.org/10.1128/asmcr.…

The Role of ß-Lactam Antibiotics in Treating Mycobacterium abscessus: From Laboratory Insights to Clinical Applications and the Case for Clinical Trials ✅ Just Accepted 🔗 bit.ly/4mH8Hwr

Just published our CID masterpiece 🎉 — nearly a decade of work on Mycobacterium abscessus Table 3-4: real clinical cases 🩺 Figure 1: science we built, our own creation💡 Next step: clinical trial — funding needed 💰 Proud moment 🙌 academic.oup.com/cid/advance-ar…

Grateful to have given a plenary talk at the 15th Annual Department of Medicine Research Day at CWRU this past Friday. It was a privilege to represent our Infectious Diseases Section, led by Dr. Usha Stiefel, and to honor my lifelong mentor, Dr. Robert A. Bonomo

@ABsteward @BradSpellberg Never liked semi-synthetic penicillins. They’re flashy for rounds, but I’m team cefazolin—low drama, high yield to the end

The most anticipated RCT in ID 🔥SNAP RCT🔥The largest RCT 2 date in SA bactermia N:1341 Cefazolin Vs ASPs ((flu)cloxacillin) for MSSA bacteremia Cefazolin is non-inferior (90d mortality)& less AKI than ASPs A practice-changer RCT that must change the guidelines #ESCMIDGlobal

@IdVilchez @apc_md @BradSpellberg @DrToddLee @ABsteward @wwrighID @dralicehan @DrRossanaRosa @drtimothyli @JonathanRyderMD @OncIDPharmd Rifampin and rifabutin both lack efficacy against MAC, as thoroughly discussed in the article you shared, including the potential “chewing” of the macrolide. If clofazimine is available, I would replace it without hesitation

#IDTwitter are others considering to move away from rifampin in the case of Pulmonary MAC treatment? pubmed.ncbi.nlm.nih.gov/38697635/ @DousaKhalid @apc_md @BradSpellberg @DrToddLee @ABsteward @wwrighID @dralicehan @DrRossanaRosa @drtimothyli @JonathanRyderMD @OncIDPharmd

🆕️✨️The largest study to date of patients with Bacteroides spp. Bacteremia Metronidazole 500mg q12h dosing was not associated with worse outcomes compared to metronidazole 500mgq8h 500mgq12h works for bactremia. It works for other infections, too sciencedirect.com/science/articl…

So thrilled to see Robert Bonomo receive the @IDSAInfo Finland Award, so deserved it..

Today we were very lucky to have Dr.Khalid Dousa From CWRU and the VA presenting his original work in M. abscessus @DousaKhalid Thank you for such a great talk

@realandyrosser @drtimothyli @jac_amr Coauthored the manuscript cited in the post- note that MAC does not produce B-lactamase, so the role of avibactam in this context is unclear to me- There is insufficient data regarding avibactam’s CNS penetration, and ceftazidime MIC against MAB is extremely high >256!

@drtimothyli @jac_amr Yes definitely. For CNS MAC

Dual β-lactam therapy works for M.abscessus Is it useful for M.avium complex (MAC) as well? Statistically significant ⬇️ of meropenem MIC was noted when it's combined with ceftaroline(CPT), cefdinir(CDR) and cefuroxime(CXM), especially with CPT and CDR doi.org/10.1093/jacamr…

@realandyrosser @drtimothyli @jac_amr MAC does not produce beta-lactamase, so the use of avibactam is unnecessary

@drtimothyli @jac_amr Cetazidime avibactam is useful and less complicated

@harvardgidoc Prince

New research finds that cefuroxime and sulopenem, when used together, display a significant synergistic effect. @DousaKhalid #mBio journals.asm.org/doi/10.1128/mb…

Early success in treating Mycobacterium abscessus pulmonary infections in child—culture conversion in 6 months & cure in 8 months with a regimen including 2 β-lactams. Could a cephem- replace amikacin, similar to what happened with E faecalis IE? journals.asm.org/doi/epub/10.11…

@IdVilchez @FungalDoc I had a similar case that became complicated due to hemophagocytic lymphohistiocytosis (HLH). Unfortunately, the patient succumbed to cytokine storm

#IDTwitter disseminated Histoplasmosis and Disseminated Crypto...very bad combo of mischievous guys to simultaneously have. Thanks to @FungalDoc for always being kind and helpful to help me with these challenging cases

Blastomycoses cases in Vermont. Quoted in this article about the changing epidemiology of fungal diseases. nbcnews.com/health/health-…

Before any major conference, I can predict who 90% of the invited speakers will be. That's fine if they are world leaders in the field,or great speakers (ideally both). And most are. But some are neither -but they are on the "circuit" and invited over and over and over again

@DrDCNguyen 😂

What are these antibiotic regimes? Are there dictatorships of antibiotics? And if so why are you so reluctant for me to topple the vanc and pip-tazo regimes?

@natesumMRSA Feel better Nate

First tweet in a while. Feeling sick (f/c, bad low back aches, mild rhinorrhea, dry cough) so I self swabbed x2 for COVID at home, both negative. It's after hours so I go to the nearby urgent care clinic. T=101.6, HR=120 😬