L.-C. Campeau Ph.D.

🚨🚨🚨 New episode alert! 🚨🚨🚨 This month’s episode features our first appearance from chemists in our London site in the UK. Come learn how EREDs can be used to access Spirocycles with David, Damien and Olivia. #MerckChemistry podcasts.apple.com/us/podcast/pha…

The last time that the Montreal Canadiens had a 40 goal scorer, the Montreal Expos were about to become the best team in baseball.

Carey Price seeing a 40 goal scorer on the Habs

Question: "Montreal hasn't had a 40 goal-scorer in 32 years, did you know that?" Cole Caufield: "Yeah, you guys talk about it a lot."

@HabsOnReddit Reminds me of Sidney’s golden goal.

What is the Habs defensive structure here exactly in a tie game with 2 mins left?

Your Habs starter tonight: Jacob Fowler

#GoHabsGo the 2nd…

Habs fans doing the wave in Ottawa with 6 minutes left in the game. Pathetic display by Sens fans tonight. Makes me fucking sick every time this happens.

That deserve a triple low-five! #GoHabsGo

JACOB. FOWLER. 😱 You need to see these saves from the last 1:10 of this game!

These two 🔥🔥

Last week's Paper-of-the-Week (POW) presentations in our weekly group meeting featured some great work by Morken Group, @BrittonLab + Pantophlet + @DrLCsquare, @CarreiraGroup, and Reisman Group + Peters Group! #chemistry #boron

Even with AlphaFold, protein structure is not a solved problem. And protein structure was never the bottleneck for drug development anyway. Let me explain.

Cole Caufield & Nick Suzuki First Canadiens teammates with 5 straight 20-goal seasons since Mats Naslund & Stephane Richer from 1985-86 to 1989-90 #GoHabsGo

Another paper from our collaboration with @BrittonLab! We’ve been focusing on novel methods to make nucleoside analogues for over 7 years now. This week we published our 2nd @ScienceMagazine paper in the area. Congrats to the team! #MerckChemistry science.org/doi/10.1126/sc…

Many congratulations to Greg Hughes (Merck) on receiving the Industry Award. @greg__hughes Greg will present his prize lecture at the 30th Congress in Sao Carlos, Brazil 🇧🇷 in July 2026. ishc-brazil2026.com

“I’ll remember François Legault for the normalization of xenophobia that’s set Quebec back a generation. I’ll remember defunded schools, overcrowded hospitals and an assault on post-secondary education.” #polqc

Who’s the most loved and trusted country with the best global reputation? Source: Reputation Institute 1st - Canada 🇨🇦 2nd - Norway 🇳🇴 3rd - Sweden 🇸🇪 Out of the top 20 countries, 15 are European Congrats to our Canadian friends, totally deserved! 🍁 worldatlas.com/articles/best-…

👋DRUG HUNTERS👋 N₂ extrusion from alkyl hydrazines delivers complex, medicinally relevant alkyl S(VI)-chemical space with exceptional chemoselectivity and operational simplicity. Appearing today in @ChemRxiv: chemrxiv.org/doi/full/10.26… Alkyl hydrazines (or their sulfonyl derivatives) serve as practical radical precursors readily prepared from ketones, alcohols, amines, and complex molecules. Simple thermal activation triggers clean N₂ extrusion to generate alkyl radicals that are captured by inexpensive SO₂ sources, delivering versatile sulfinates convertible in situ to sulfonyl fluorides or sulfinamides. 70+ examples, protecting-group-free late-stage functionalization of natural products and drugs (ticagrelor, erythromycin, spiramycin), 100-g scale with trivial work-up, and stereoretentive variants round out a unified platform that directly addresses the growing need for complex alkyl S(VI) motifs in medicinal chemistry. Detailed mechanistic studies, including temperature scanning calorimetry, radical clocks, and DFT calculations help to demystify the process.

New paper alert!!! 🚨🚨🚨 We report "A unified platform for nucleoside analog synthesis" in @ScienceMagazine Congratulations to Matthew, Ethan, the rest of the team and our @Merck collaborators @DrLCsquare and @asymtmm for this monumental publication! science.org/doi/10.1126/sc…