L.-C. Campeau Ph.D.

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L.-C. Campeau Ph.D.

L.-C. Campeau Ph.D.

@DrLCsquare

Head of Small Molecule Process R&D at Merck. Trying to change the world, 1 reaction at a time. Fellow of the Royal Society of Canada. Cohost @PharmToTablePod

New York Metropolitan Area Katılım Mart 2011
1.1K Takip Edilen8.6K Takipçiler
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L.-C. Campeau Ph.D.
L.-C. Campeau Ph.D.@DrLCsquare·
🚨🚨🚨 New episode alert! 🚨🚨🚨 This month’s episode features our first appearance from chemists in our London site in the UK. Come learn how EREDs can be used to access Spirocycles with David, Damien and Olivia. #MerckChemistry podcasts.apple.com/us/podcast/pha…
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Jared Book
Jared Book@jaredbook·
The last time that the Montreal Canadiens had a 40 goal scorer, the Montreal Expos were about to become the best team in baseball.
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/r/Habs
/r/Habs@HabsOnReddit·
Carey Price seeing a 40 goal scorer on the Habs
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Marco D'Amico
Marco D'Amico@mndamico·
Question: "Montreal hasn't had a 40 goal-scorer in 32 years, did you know that?" Cole Caufield: "Yeah, you guys talk about it a lot."
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/r/Habs
/r/Habs@HabsOnReddit·
What is the Habs defensive structure here exactly in a tie game with 2 mins left?
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/r/Habs
/r/Habs@HabsOnReddit·
Your Habs starter tonight: Jacob Fowler
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Martian
Martian@LalimesMartian·
Habs fans doing the wave in Ottawa with 6 minutes left in the game. Pathetic display by Sens fans tonight. Makes me fucking sick every time this happens.
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NHL
NHL@NHL·
JACOB. FOWLER. 😱 You need to see these saves from the last 1:10 of this game!
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Sportsnet
Sportsnet@Sportsnet·
These two 🔥🔥
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Ming "Tommy" Tang
Ming "Tommy" Tang@tangming2005·
Even with AlphaFold, protein structure is not a solved problem. And protein structure was never the bottleneck for drug development anyway. Let me explain.
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Sportsnet Stats
Sportsnet Stats@SNstats·
Cole Caufield & Nick Suzuki First Canadiens teammates with 5 straight 20-goal seasons since Mats Naslund & Stephane Richer from 1985-86 to 1989-90 #GoHabsGo
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Cult MTL
Cult MTL@cultmtl·
“I’ll remember François Legault for the normalization of xenophobia that’s set Quebec back a generation. I’ll remember defunded schools, overcrowded hospitals and an assault on post-secondary education.” #polqc
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Cult MTL@cultmtl

Like every other conservative politician who’s run out of ideas, François Legault continues to blame immigrants and minorities for his failed economic politicies. #polqc cultmtl.com/2026/01/thanks…

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Elisa Mosini 🇪🇺🇮🇹
Who’s the most loved and trusted country with the best global reputation? Source: Reputation Institute 1st - Canada 🇨🇦 2nd - Norway 🇳🇴 3rd - Sweden 🇸🇪 Out of the top 20 countries, 15 are European Congrats to our Canadian friends, totally deserved! 🍁 worldatlas.com/articles/best-…
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Baran Lab
Baran Lab@BaranLabReads·
👋DRUG HUNTERS👋 N₂ extrusion from alkyl hydrazines delivers complex, medicinally relevant alkyl S(VI)-chemical space with exceptional chemoselectivity and operational simplicity. Appearing today in @ChemRxiv: chemrxiv.org/doi/full/10.26… Alkyl hydrazines (or their sulfonyl derivatives) serve as practical radical precursors readily prepared from ketones, alcohols, amines, and complex molecules. Simple thermal activation triggers clean N₂ extrusion to generate alkyl radicals that are captured by inexpensive SO₂ sources, delivering versatile sulfinates convertible in situ to sulfonyl fluorides or sulfinamides. 70+ examples, protecting-group-free late-stage functionalization of natural products and drugs (ticagrelor, erythromycin, spiramycin), 100-g scale with trivial work-up, and stereoretentive variants round out a unified platform that directly addresses the growing need for complex alkyl S(VI) motifs in medicinal chemistry. Detailed mechanistic studies, including temperature scanning calorimetry, radical clocks, and DFT calculations help to demystify the process.
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