Patrick May
55 posts


after Karen Bass tells Trump that reconstruction will start after hazardous waste is removed, Trump says, "what's hazardous waste? I mean, you're gonna have to define that. We're gonna through a whole series of questions on determining what's hazardous waste? I just think you have to let the people go on their site and start the process tonight."
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New online! Intracerebral haemorrhage — mechanisms, diagnosis and prospects for treatment and prevention go.nature.com/4evLglJ

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@adamfeuerstein Agree, but would point out that the active ingredient of KarXT goes back to Eli Lilly/Novo Nordisk collaboration when they put the drug, xanomeline, into a Phase 2 Alzheimer’s trial for cognition in the 1990’s. The drug failed due to cholinergic side effects that limited dosing.
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One of the most satisfying aspects of covering biotech as long as I have is the opportunity to report on the long arc of drug development, from start to finish. It's not always pretty, and more often than not, it ends badly.
But KarXT, now Cobenfy, is one of those drug stories with a happy ending. I remember talking to Steven Paul in 2019 for a story about the phase 2 results, which were pretty remarkable. Paul was excited about what KarXT might mean for people with schizophrenia, but he was cautious because, as he warned me at the time, clinical trials for psychiatric conditions are extraordinarily difficult to replicate. Let's wait to see what KarXT does in Ph3 trials, he said.
Now, we know.
It's been cool to follow and report on the KarXT story all these years. From PureTech to Karuna to Bristol Myers Squibb, and now, to approval, where Cobenfy will have a meaningful impact on people living with schizophrenia.
statnews.com/2024/09/26/fda…
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@Super70sSports Did you know that this song is partially written about a girlfriend of his that he had to quit - she was too on the edge for him. She shows up later in LA at the Chateau Marmont giving John Belushi the cocaine/heroin hotshot that killed him. Smart move by Lightfoot.
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@BeschlossDC My late wife and I were on our first vacation together, camping in the Smoky Mountains. We had a radio but agreed to not turn it on unless there was an emergency. We broke down the last night of our trip and were stunned to hear Nixon’s voice. Not a visual but a strong memory.
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Please RT & share 🗣
Let’s reach #FirstGen & other undergrads & postgrads who might be inspired by this! 💭
Interested in the brain, biology or medicine? 🤔
Access the largest dementia conference in the world for free as a student! 🌎
@alzassociation @ISTAART #AAIC22 🧠💜
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@boutodeletethis @EricTopol This bar graph makes no sense to a scientist.
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Most people around the world are eager to get vaccinated, but in the US it has sadly required mandates, which are working
"Employers that introduced mandates saw the share of vaccinated workers climb as much as 20 percentage points to hover around 90 %"
ft.com/content/865a6d…


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Patrick May retweetledi

Patrick May retweetledi
Patrick May retweetledi
Patrick May retweetledi
Patrick May retweetledi

Let’s make Eugene Goodman trend.
Rev. Dr. Don (PhD)@DonHargrove2
HERO. TRUE PATRIOT. EUGENE GOODMAN The man who saved the Senate Officer Goodman stopped a mob of white rioters from entering the chambers of the US Senate. At this perilous moment in our nation’s history, he was the one person standing between democracy & rule of tyrants
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Patrick May retweetledi
Patrick May retweetledi


That was one of the most disturbing images - seeing those clowns drop an American flag over a balcony in their effort to raise a Trump flag up the flagpole.
Angry Staffer@Angry_Staffer
Remember when kneeling was disrespectful to the flag then they took the American flags down at the Capitol and replaced them with Trump flags? It’s almost like it was never about the flag.
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@anncsborne when does Schumer assume his role as Senate Majority Leader?
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@morningmika Love your show and perspective, but I think this was taken before the actual storming of the capitol building. Still painful to watch knowing what happened subsequently.
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