Davide Tamborrini

23 posts

Davide Tamborrini

@DvdGently

Postdoc @biozentrum and marathon swimmer - @mpimoph alumnus

Basel - Switzerland Katılım Mayıs 2020

281 Takip Edilen170 Takipçiler

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Davide Tamborrini@DvdGently·1 Kas

Our structures of the #cardiac #sarcomere are now published in @Nature! With #teamtomo at @intein lab, we've used #CryoET to unveil how #myosin and #actin filaments arrange in #muscle relaxed with #mavacamten. Great collaboration with Gautel Lab! doi.org/10.1038/s41586… 🧵

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Davide Tamborrini@DvdGently·9 Eki

Honored to be awarded the Biochemistry Prize by the German Chemical Society. I am very grateful for this recognition and excited for the future!

MPI Dortmund@mpimoph

Congrats to @DvdGently former scientist in the @intein group on receiving the Förderpreis Biochemie of the @GDCh_BioChem @GDCh_aktuell #teamtomo #CryoEM

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Wout Oosterheert@WoutOosterheert·11 Nis

Our latest work on #actin assembly is now online @ScienceMagazine! We show how #formins bind and move with the growing barbed end of F-actin. Awesome collab. between @Intein and Bieling labs @mpimoph, and big thanks to co-first author @maikaboiero science.org/doi/10.1126/sc…

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Oleg Sitsel@oleg_sitsel·19 Oca

Our paper revealing how specialized #Yersinia cells 🦠release a deadly Tc toxin-containing cocktail ☣️ by blowing themselves up 🧨🤯 is finally out! Read it in @naturemicrobiol: nature.com/articles/s4156… #toxin #pathogen #tomography #explosion #T10SS

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Oleg Sitsel@oleg_sitsel·23 Oca

My lab has exciting openings for postdocs/staff scientists and a technician. Involves super-cool projects, a dynamic international environment, cutting-edge infrastructure, and a stunningly beautiful tropical island! oist.jp/careers/two-po… oist.jp/careers/resear… Please repost!

Oleg Sitsel@oleg_sitsel

It is my great pleasure to announce that I am joining @OISTedu as faculty! My lab will focus on characterizing our oceans’ amazing inhabitants mainly by cryo-electron #tomography, with #corals representing our chief interest. Collaborators always welcome – please reach out to me!

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Nature Reviews Cardiology@NatRevCardiol·15 Kas

Two papers in @Nature describe the structure and conformation of myosin in the cardiac thick filaments and how it interacts with other proteins, such as titin and cMyBP-C, in mammalian hearts ($): doi.org/10.1038/s41569… @DvdGently, @intein, @raulpadron #ResearchHighlight

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Davide Tamborrini@DvdGently·4 Kas

That makes for a great start! Congrats to all of you!

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Davide Tamborrini@DvdGently·2 Kas

@SchnorrerL @Intein Swimming 🏊🏼‍♂️ 16k from Corsica to Sardinia, roughly the length of 2 X 10^10 titin chains 🔬😄

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Frank Schnorrer@SchnorrerL·2 Kas

Seeing titin in situ!! So cool. Congrats @DvdGently @Intein - Swimming or cycling from France to Italy?? 😄

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Davide Tamborrini@DvdGently·1 Kas

9/🧵This has been an incredible journey! My gratitude to @intein, especially for providing a great environment to thrive in. Special thanks to the fellow co-authors, and kudos to @Alexxxxx_Xu and @BaptisteColCaz for the music in the video! 🎸🎹

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Davide Tamborrini@DvdGently·1 Kas

8/🧵Cardiovascular diseases are the leading causes of death worldwide. The cardiac muscle is the engine that keeps us running. This work, together with the work from Craig-Padron Lab (@raulpadron), wants to provide a blueprint to better understand the engine at a molecular level.

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Davide Tamborrini@DvdGently·1 Kas

1/🧵 Using our #FIBmilling workflow, we prepared lamellae from left ventricular #myofibrils and focused our #CryoET beam on the central regions of the A-band and targetting the C-zone. We resolved the thick and thin filaments in the relaxed state with resolutions ranging 8-24 Å.

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Davide Tamborrini@DvdGently·1 Kas

@raulpadron @Nature Congrats to you all! 2023: the year of the cardiac thick filament! Beautiful work 🤩🔬

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Raúl Padrón@raulpadron·1 Kas

Our paper is now in @Nature: #CryoEM 6 Å reconstruction of #human cardiac thick filament C-zone in #mavacamten, showing #myosin heads, tails, #titin, #MyBP-C. Many implications for a 60-year mystery on #cardiac #muscle #physiology, #structure and #disease. shorturl.at/mwU16

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Davide Tamborrini@DvdGently·22 Eki

@bengeliscious 😅well, you nailed it: it helps with buoyancy 😂

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Ben Engel@bengeliscious·22 Eki

@DvdGently That's amazing, Davide! Achievement unlocked, indeed! As for me, #EatPastaBellyGrowFasta😅

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Davide Tamborrini@DvdGently·22 Eki

🌊 Swam ~16km from Corsica to Sardinia! 🏝️ 5 hours of pure enjoyment and adventure. The view from the ISS really puts it all into perspective. 🛰️ 😍 #MarathonSwimming #AchievementUnlocked #WorthTheSweat #EatPastaSwimFasta 🍝🏊‍♂️

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Keşfet

@ScienceMagazine @mpimoph @maikaboiero @NatureMicrobiol @Nature @raulpadron @SchnorrerL @Alexxxxx_Xu