EpicentRx, Inc.

It's already the end of July - how time does fly! The highlight of Q2 was Dr. @APConley77's epic ASCO oral presentation on AdAPT-001. EpicentRx also plans to make a big splash 💦 in Q3. Stay tuned here: bit.ly/4c5021y.

The 1967 film, The Dirty Dozen, could have been called the “Dirty Cozen” given the degree of mind f**ery that occurs to convince a ragtag bunch of violent convicts to lead a suicide mission behind enemy lines. Read more here: bit.ly/3OCIf8S.

Fire up the Bat Signal. The combination of AdAPT-001 plus an immune checkpoint inhibitor signals the immune system to go on the offensive against tumors. Read more here: bit.ly/3VbW4OW. #BatSignal #TheBatman #AdAPT001

What’s the word this Thanksgiving? For the answer ask Peter Griffin from Family Guy and read this Thanksgiving e-card here: bit.ly/4fIXR6r.

The recent backdrop of the very polarizing US Presidential election serves as the central analogy for an EpicentRx-authored article about macrophages in the December edition of PharmaTimes. Read more here and cast your vote on this well-written article entitled “Outside the Box”: bit.ly/3ANedfl

The EpicentRx Word of the Week is crassulent, which means obese. Read more here: bit.ly/495602K.

“Please sir I want some more” is a famous line from Charles Dickens’ novel, Oliver Twist. Hopefully, that line also applies to these blog posts. Incidentally, in a “twist” EpicentRx might travel to Australia for a stretch, like the Artful Dodger character from the novel. Read here: bit.ly/4hVXQ0z

Mad, bad, and dangerous or delightful to NO describes, not Lord Byron, the 19th century English poet, but lead EpicentRx therapy, RRx-001 (nibrozetone), which releases nitric oxide (NO) under hypoxic and acidic conditions. Read more here: bit.ly/3Ze6Jeq.

A typecast actor is one who repeatedly plays the same part. A targeted therapy is “typecast” against one specific disease process. #RRx001 (#nibrozetone) is “un-typecastable” as a #multitargeted therapeutic. Read more here: bit.ly/3UZPPxN.

Marty Feldman who played Igor (pronounced eyegor) in Young Frankenstein and who suffered from Graves’ ophthalmopathy was the embodiment of swivel-eyed, a chiefly British term. Read more here: bit.ly/4hTh32O.

Several overused, cliched phrases grate on us like nails on a chalkboard. “To your point” screeeeeech! is one. Another is “existential threat” screeeeeech! which is used so often as to render it meaningless. Read here: bit.ly/4g6XJh9.

Since chronic conditions put the scare into us all year round, we thought to return the favor with these post-Halloween “misfortune cookies”. Break them open here to discover what grim fate awaits these conditions: bit.ly/3rAZ2RG.

#FortKnox is synonymous with gold bullion. Fort NOx aka #RRx001 (#nibrozetone) which releases therapeutic nitrogen oxides (NOx) in diseased tissues, is synonymous with #platinum. Read more here: bit.ly/3ULS9IA.

Boxer Mike Tyson refers to himself as a “natural born killer” and his opponent, YouTuber Jake Paul, as a “manufactured killer.” Lead EpicentRx therapy, AdAPT-001, is both. Read more in this blog here: bit.ly/3ULQT8c.

The tasty EpicentRx Word of the Week is toothsome: bit.ly/491yFpv.

Learn more at #SITC24. Visit @APConley77 at his poster presentation on the remarkable clinical activity of #AdAPT001+ checkpoint inhibitors in sarcoma and other tumor types. Click here: bit.ly/4fyILzS.

Check out this new cartoon in our weekly Friday Funnies: bit.ly/4eCzx57.

The most maligned group of medical practitioners are “fascia-ists” comprising massage therapists, physical therapists, sports medicine specialists, and surgeons. Read this entertaining blog here: bit.ly/3UHtSDk.

According to Ricky Bobby from #TalladegaNights, “If you ain’t first, you’re last.” The motto of lead EpicentRx therapy, AdAPT-001, could well read “to be first is worst” because it takes time to develop an effective antitumor response: bit.ly/4efV5UJ.

#ElonMusk has written repeatedly about “the woke mind virus.” Lead EpicentRx therapy, AdAPT-001, is the only woke virus that Elon would not vehemently dislike because it wakes up the dormant immune system to attack tumors: bit.ly/4egKxVl.

The word psephology literally means “rock the vote.” Read more about it in EpicentRx’s Word of the Week: bit.ly/3YMu4nn.