Eric Macy

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Eric Macy

Eric Macy

@EricMacyMD

Clinical Immunology Allergy. Kaiser Permanente. Drug Hypersensitivity. KPSC IRB Chair.

San Diego, CA Katılım Mart 2014
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Eric Macy
Eric Macy@EricMacyMD·
At Kaiser Permanente we have removed all warnings not to use cephalosporins in the setting of a penicillin "allergy", including the very rare history of penicillin-associated anaphylaxis. @KPSCalResearch jaci-inpractice.org/article/S2213-… jaci-inpractice.org/article/S2213-… jamanetwork.com/journals/jaman…
Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟@ABsteward

Would love to hear from @EricMacyMD @TrubianoJason @blandman19 Would you consider this case as anaphylaxis with this limited info/time? Do you consider anaphylaxis a reason not to give cefazolin or to be cautious in penicillin allergy? #IDtwitter

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Eric Macy
Eric Macy@EricMacyMD·
Perhaps we should change the name of the field in the EHR to WICAs, warnings, intolerances, cautions, and allergies to account for the reasons no to use or reuse a material or drug. Allergy Lists: Ubiquitous, but Flawed doximity.com/newsfeed/1e28d… via @doximity
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Neil Stone
Neil Stone@DrNeilStone·
"Most people who say they are allergic to penicillin,aren't really, and can safely be given pencillins"
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Mariam Hanna MD
Mariam Hanna MD@PedsAllergyDoc·
Corticosteroids (in case you're going to think about it) has ZERO evidence to prevent biphasic reactions. First generation antihistamines should NEVER be used in the context of anaphylaxis. Stay away! If you're even going to consider it, use 2nd and 3rd generation. #CSACI23
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United States Drug Allergy Registry
(1/9) The USDAR (United States Drug Allergy Registry) group presents a consensus-developed, standardized, severity grading scale for immediate drug reactions in adults. This scale applies to both clinical care and research. sciencedirect.com/science/articl…
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Eric Macy
Eric Macy@EricMacyMD·
The next lowest dose of a beta-lactam inducing fatal anaphylaxis that I could find was in a case report: applications.emro.who.int/emhj/0602_3/em… Intradermal test dosing done with 0.2 ml of 300,000 IU/ml penicillin G or about 36 mg of penicillin.
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Eric Macy
Eric Macy@EricMacyMD·
An important lesson here. Anaphylaxis occurred with systemic exposure to only about 0.5 mg of ampicillin. ID skin testing (0.02ml) using ampicillin 25 mg/ml. Use 0.01 molar for beta-lactams. Fatal ampicillin-sulbactam anaphylaxis in a 34-year-old male jaci-global.org/article/S2772-…
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Eric Macy
Eric Macy@EricMacyMD·
#relatedArticles" target="_blank" rel="nofollow noopener">jaci-inpractice.org/article/S2213-…
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Kimberly Blumenthal, MD, MSc
Kimberly Blumenthal, MD, MSc@KimberlyBlumen1·
👀💊9/28 is National Penicillin Allergy Day! I devoted much of my career to studying the negative impact of taking a reported penicillin allergy as truth and using alternative antibiotics. Some adverse consequences are preventable through penicillin allergy evaluation 1/3
Kimberly Blumenthal, MD, MSc tweet media
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