Chad Johnston

Happy to finally be announcing that I’ll be joining the Baylor College of Medicine as an assistant professor and CRPIT scholar starting January 2022!

Well, it took a little longer than expected, but we're happy to share our lab's first paper. Thanks to the reviewers and editors at JACS for sticking with us through a surprisingly weird story 😅. Science never changes. pubs.acs.org/doi/10.1021/ja…

@med_chemist "Have a HTS return no useful hits" should have a trigger warning.

5 easy steps to become a modern grumpy med chemist: - Have a HTS return no useful hits - Have a virtual screen return no useful hits - Have a fragment screen return no useful hits - Have a DEL screen return no useful hits - Have a literature compound fail to reproduce

@vhvsynth I'm dying to know: can you taste the spice in the air when you're making this thing? Awesome work btw!

It’s been an honor to spearhead this project - finally out! Grateful to everyone involved!

@wildtypeMC Comments already have quotes-for-everything and NEB. You'll need to also do the math on vendor pricing to find the best deals. Glassware and other odds and ends can generally be had from older labs that'll give them away for free. Buy used if you're brave or can fix things.

Since I started my lab just a few weeks ago, is there any sort of New PI discount you'd be able to apply to these? Cost will be a major factor, so any discount you could apply would be much appreciated. Thanks for your help and talk to you soon.

@GeoSantiagoM @wildtypeMC This. I think there's a cap of $5k or something, but it's significant savings.

@wildtypeMC New England Biolabs offers this one-time 40% discount to Principal Investigators who are starting up a new lab. neb.com/support/new-la…

@ZachReitzPhD Is the beta-hydroxy histidine new? Don't know that I've seen that in siderophores before...

Looking forward to software that can optimally place chelating atoms in a skeletal structure so I don't have to wrangle it by hand.

@MoleculesGoHard I'm stealing this and using it for all molecules of interest from now on. Thanks.

Where be your Pd(dppf)Cl2·DCM?

@wildtypeMC Black Vans lows are the only acceptable shoe for new PIs. Change my mind.

Only one wearing shorts and cross trainers at the New Faculty dinner lol

It's not necessarily science, but I'm exposed through my better half. Kyla Scanlon is the best finance follow out there.

A new paper from Kim Lewis identified a natural product Evybactin targeting DNA gyrase and killing Mycobacterium tuberculosis via a selective transport mechanism. Free to read link at rdcu.be/cUmNn

New LCMS just dropped.

First Johnston lab outing! Great time with the team, plus I learned I can't take group selfies AND look normal. Maybe one day.

Me - a new PI with a freezer already full of bacterial extracts

@SophieLNixon @katcoyte @BiotechDixon @BrockhurstLab @knightjjar @Hepworth_Lab @OfficialUoM @SustainableUoM @DigitalUoM Congrats!

Exciting times ahead! Myself, @katcoyte, @BiotechDixon, @BrockhurstLab, @knightjjar and @Hepworth_Lab have been awarded funds to establish @OfficialUoM as an international centre for microbiome research! 🔬🦠🧬🖥️ Thanks for the support @SustainableUoM @DigitalUoM 🙏

Hey aspiring PIs! Looking for a Prof position that comes with a cool neighbour? My department is hiring ! Come see everything Baylor, Houston, and the Texas Med Centre have to offer! (spoiler: it's a lot) nature.com/naturecareers/…

@14Kountz Geosmin and a gradient of prodigiosin (plus a secret ingredient... that appears to be however close they are to the incubator air vent)

Taste the Streptomyces rainbow (but really you probably shouldn't even if it's BSL1... but maybe?)

@wildtypeMC *laughs in Houston*

What have I done?

@NadineZiemert To be fair, he does clarify many natural product mysteries!

@NadineZiemert Jon Clarify stays winning!