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Chad Johnston
110 posts

Chad Johnston
@EvolvedChem
Assistant professor and CPRIT Scholar at the Baylor College of Medicine in Houston, starting Jan 2022. Discovery and directed evolution of natural products 🦠
Houston TX; Previously Toronto Katılım Temmuz 2020
146 Takip Edilen166 Takipçiler

Well, it took a little longer than expected, but we're happy to share our lab's first paper. Thanks to the reviewers and editors at JACS for sticking with us through a surprisingly weird story 😅. Science never changes.
pubs.acs.org/doi/10.1021/ja…
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@med_chemist "Have a HTS return no useful hits" should have a trigger warning.
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@vhvsynth I'm dying to know: can you taste the spice in the air when you're making this thing? Awesome work btw!
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@wildtypeMC Comments already have quotes-for-everything and NEB. You'll need to also do the math on vendor pricing to find the best deals. Glassware and other odds and ends can generally be had from older labs that'll give them away for free. Buy used if you're brave or can fix things.
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@GeoSantiagoM @wildtypeMC This. I think there's a cap of $5k or something, but it's significant savings.
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@wildtypeMC New England Biolabs offers this one-time 40% discount to Principal Investigators who are starting up a new lab.
neb.com/support/new-la…
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@ZachReitzPhD Is the beta-hydroxy histidine new? Don't know that I've seen that in siderophores before...
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@MoleculesGoHard I'm stealing this and using it for all molecules of interest from now on. Thanks.
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@wildtypeMC Black Vans lows are the only acceptable shoe for new PIs. Change my mind.
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It's not necessarily science, but I'm exposed through my better half. Kyla Scanlon is the best finance follow out there.
Kyla Scanlon@kylascan
Jackson Hole Recap
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Chad Johnston retweetledi

A new paper from Kim Lewis identified a natural product Evybactin targeting DNA gyrase and killing Mycobacterium tuberculosis via a selective transport mechanism. Free to read link at rdcu.be/cUmNn

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Me - a new PI with a freezer already full of bacterial extracts
60% Water By Mass@MoleculesGoHard
Industry has spoiled me
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Exciting times ahead! Myself, @katcoyte, @BiotechDixon, @BrockhurstLab, @knightjjar and @Hepworth_Lab have been awarded funds to establish @OfficialUoM as an international centre for microbiome research! 🔬🦠🧬🖥️ Thanks for the support @SustainableUoM @DigitalUoM 🙏
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Hey aspiring PIs! Looking for a Prof position that comes with a cool neighbour? My department is hiring !
Come see everything Baylor, Houston, and the Texas Med Centre have to offer! (spoiler: it's a lot)
nature.com/naturecareers/…
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@14Kountz Geosmin and a gradient of prodigiosin (plus a secret ingredient... that appears to be however close they are to the incubator air vent)
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@NadineZiemert To be fair, he does clarify many natural product mysteries!
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