M Velia Antonini

TA #NRP in cDCD heart donors using closed #ECMO circuit, modified to provide 🩸🌡️effective NRP despite prolonged fWIT 🫀LV venting 🫀 fast conversion to central configuration as needed ⭕️ shunt for recirculation 🫧 air management #FOAMcc @asaiojournal 🔓bit.ly/TANRPasaio TA-NRP using fully mobile, closed #ECLS circuit could be safe strategy to support combined thoracic/abdominal organs recovery also in peripheral centers without cardiac surgery program, contributing to the expansion of DCD programs, increasing availability/quality of grafts, improving recipients’ outcome. @ESOTtransplant @gabriel_oniscu @LuPoten @Unibo @AUSLRomagna

🫘 Extracorporeal membrane oxygenation, acute kidney injury, fluid balance, and continuous renal replacement therapy: Acute Disease Quality Initiative ADQI and ELSO - Extracorporeal Life Support Organization joint consensus conference Open @yourICM 🔓 rdcu.be/fh662

ECMO, acute kidney injury, fluid balance, and continuous renal replacement therapy: 🫘 epidemiology, risk factors, outcomes of #AKI & #CRRT 💦 fluid management and outcomes 📋 indications for CRRT and fluid removal during #ECMO, and best practices for performing 💉 biomarkers, extracorporeal blood purification, drug PK/PD ADQI and @ELSOOrg joint consensus conference, aimed at providing recommendations, identifying knowledge gaps and research priorities based on international expert consensus, to serve to lay the foundation for a standardized approach across #ECLS centers #FOAMcc #FOAMecmo @yourICM 🔓 rdcu.be/fh662

🫁 🫘🫀 Standing room only for the 3 sessions of the normothermic regional perfusion #EducationalCorner at #EuroELSO2026! Let me acknowledge the participants for demonstrating their interest in the (rapidly) evolving and expanding topic of #NRP to support organ recovery from DCD donors, and the experts/trainers for supporting this education and training workshop during the congress. Thanks @EuroELSO for hosting us for the third year in a row!

#ECMO considerations, cultures, families, ethics: ⚖️ conflicting patients wishes 📜 bridging the gap in bidirectional consent 🚧 decision making about withdrawal 🕯️ concept of death and donation Heading to #EuroELSO2026, the 14th annual congress of EuroELSO?? join us for this round-table discussion (& prepare your questions ⁉️) Where?? 📌 RDS Dublin 🇮🇪 📆 Saturday, May 9 ⏰ 8:30 – 10:00

Are you planning to start an NRP program? Are you at the beginning of your DCDD experience? Or do you want to learn more about how DCDD/NRP is performed in other countries or institutions? Come to join the Normothermic Regional Perfusion Educational Corner at the #EuroELSO2026 congress! We will focus of the use of NRP to support organ recovery & #transplantation in DCD donors. A group of international experts from 🇮🇹, 🇪🇸 & 🇬🇧 will lead an interactive case based discussion on A and TA #NRP, simulating real life scenarios. Our international trainers, including perfusionists, surgeons and intensivists will provide you clinical & technical tips & tricks 📆 Friday, May 8, 2026 ⏰ 1st session 10:15 – 11:45 ⏰ 2nd 13:00 – 14:30 ⏰ 3rd 14:45– 16:15 📌 ROOM 2, RDS - Dublin 🇮🇪 No booking required: arrive on time 5-10' before initiation to reserve your 🪑

Post-decannulation mortality in patients on VA #ECMO for cardiogenic shock 🔍 588 patients, 2011 to 2023; 71% survived to decannulation 🪦 nearly ¼ died post-decannulation, before discharge: they were older and more likely to have CKD, prior stroke, longer run duration, #Impella use 🪦 leading cause of death withdrawal of care 🫀 ECPR, post-cardiotomy shock, age, independently predicted in-hospital mortality Successful weaning key milestone, but it should not be equated with recovery. Identifying patients at risk for late in-hospital mortality and improved post-decannulation risk stratification + supportive strategies pivotal to optimize outcomes. @asaiojournal 🔗 bit.ly/3QK8yOB

The six phases of prolonged VV #ECMO, conceptual framework & key considerations during each phase: 🫁 phase 1️⃣ ➡️ ultra-lung-protective ventilation 🫁 phase 2️⃣ ➡️ lung protective ventilation 🫁 phase 3️⃣ ➡️ transition to spontaneous breathing 🪽 phase 4️⃣ ➡️ liberation trial 🩸 phase 5️⃣ ➡️ decannulation ⛓️‍ phase 6️⃣ ➡️ post-decannulation The identification of these distinct phases draws attention to specific unanswered questions, with particular reference to ventilator management and allowing patient respiratory effort with spontaneous modes of ventilation. Open access #FOAMcc #FOAMecmo @Crit_Care 🔓 rdcu.be/fgugP

🔥 Hot perfusion topics in #ECMO & #ECLS... Heading to #EuroELSO2026? DoN'T miss the joint @EuroELSO & @The_EBCP session: Topics: ⌛️ Coming to the end: how to declare death on ECMO (and support organ recovery) 🫀 The role of perfusionists in the cath lab: from stand-by to ECMO 🩸 To return or not to return the residual blood volume from the circuit? 🔍 Results of survey on the role of the perfusionist in ECLS management 🎙️ Round-table discussion 📌 RDS, Dublin 🇮🇪 Ireland 📆 Friday, May 8 2026 ⏰ 8:30 – 10:00

Adding regional citrate anticoagulation (RCA) to heparin for CRRT in VV-ECMO? 🩸 0% vs 18% circuit clotting 📈 Better platelet trends ⏱️ Longer circuit lifespan ⚖️ No relevant metabolic complications Read our randomized crossover study 👇 sciencedirect.com/science/articl…

Ethical challenges of #ECMO? 4️⃣ four domains: ⚖️ equitable ECMO candidacy decisions 🕯️ integration of palliative care and clinical ethics ⛔️ preservation of patient autonomy when institutional or benchmarking pressures influence care 🚧 responding to requests to continue ECMO when there is no exit strategy Ethical tension of #ECLS may generate moral distress for clinicians, patients, and families: here recommendations to emphasize transparent, team-based decisions, early involvement of ethics and palliative care, and consistent processes for ongoing review of candidacy and continuation of ECMO. @asaiojournal 🔗 bit.ly/4cSrUZd

🩸💧In/ex-situ perfusion/preservation for #transplant Heading to Dublin for #EuroELSO2026?? You doN'T want to miss this amazing joint session with ECTTA section of @ESOTtransplant 🎙️ Moderators @Dra_BelloIrene @FOAMecmo @SilviaMarianiMD Topics & speakers: 🫀 The heart: update on approaches to improve heart recovery and cardiac #Tx outcome @BermanMarius 🫁 The lung: how to optimize lung Tx using advanced recovery/preservation strategies - S Lindstedt 🫘 The abdominal organs: enhance liver & kidney recovery/transplant using NRP and ex-situ techniques @DominicMSummers 🛌 The donor: how to manage the donor at best to improve procurement feasibility and #transplantation outcomes? Antonio Rubino 🎙️ Discussion (prepare your questions ⁉️) During the session, we will be pleased to hear about the results of a study on long term ex-situ normothermic heart perfusion using in an in-vivo model, selected as oral abstract, presented by Zhuldyz Nurmykhametov. Where?? 📌 RDS - Clyde Hall, Dublin 🇮🇪 Ireland 📆 Friday, May 8 - 2026 ⏰ 17:00 – 18:30

BMI & survival in children receiving #ECMO? 🔍 ELSO Registry analysis, including 9K children (29 days to 18 years) receiving #ECLS from 2019 to 2023 ⚖️ 72.5% had a normal weight, 16.4% underweight, 11.1% obesity; hospital survival 61.2%, significantly lower if underweight = 58.2% and obesity = 57.4% vs normal weight Both underweight and obesity status prevalent in this population, and independently associated with increased hospital mortality; pattern persisted across subgroup analyses based on age and diagnosis leading to cannulation. BMI-based nutritional status may help guide ECMO candidacy and nutritional management during the run. #FOAMcc #PedsICU @JAMANetworkOpen 🔓 bit.ly/3P4MOwk Coming with editorial on weighing up pediatric ECMO candidacy 🔓 bit.ly/4ucMuKY

📢 Train the Trainers ECMO - European edition: website is live! 🖥️ elsobcn.org The course to prepare #ECMO educators to design, deliver, evaluate high-quality, simulation-based training 🎯 for ECMOlogists, with experience (min 5-7 y) 📆 15-17 July 2026 📌 Barcelona

#ECMO in patients with traumatic brain injury and/or requiring neurosurgery: outcomes, complications & management considerations 🧠 TBI should not be considered an absolute contraindication: #ECLS can be safely utilized. Successful outcomes relied on collaborative efforts + minimally intensive anticoagulation. A subset of patients developed ICH on ECMO (TBI/not), requiring neurosurgical interventions: key factors affecting prognosis included ICH size, timing of intervention, careful adjustment of anticoagulation. Discontinuing ECMO prior to intervention may be advantageous if clinically feasible. #FOAMcc #FOAMecmo @NeurocritCareJ 🔓 rdcu.be/fd9n9

Join the joint @ISHLT & @ESOTtransplant ECTTA symposium at #ISHLT2026, dedicated to technical aspects, controversies, outcomes, techniques for DCD heart & lung recovery with normothermic regional perfusion 🩸 #NRP: technical, ethical, and economic dimensions in heart and lung #transplantation: 🇺🇸 North American & 🇪🇺 European perspectives 🫀 🫁 rethinking recovery: ANRP with thoracic organ rapid recovery, post-recovery perfusion devices, and the next frontier in heart and lung retrieval 🚧 pushing the limits: extending ischemic boundaries with TA-NRP and other recovery platforms 🎙️ panel discussion 📆 April 24, 2026 ⏰ 8:15 - 9:30 am 📌 Metro Toronto Convention Centre Toronto, ON Canada 🇨🇦; Room 714-716 & visit the #ESOT_ECTTA Booth (🚪129)

Flow control & oxygenation of preservation solution in cDCD donors undergoing abdominal normothermic regional perfusion 🔍 study to assess feasibility, safety & effectiveness of controlled strategy of CPS administration/oxygenation employing NRP circuit & cannulae 🧊 administration of CPS through #NRP circuit is safe, feasible & effective in ensuring a controlled, fast, consistent flow, achieving prompt induction of hypothermia 💨 fresh gas flow delivery through #ECMO membrane lung may significantly increase CPS O2 tension 💧 hyperoxygenation of blood-free perfusate might provide a metabolic substrate to the cells, preconditioning liver & kidneys before cold ischemia Open access #FOAMcc 🔓 bit.ly/4mwb2vI

Viability criteria for liver NRP @RAPCOP_AST amazing webinar, speaker🎙️ @DavideGhinolfi 🩸Normothermic Regional Perfusion promising tool to provide liver assessment, improve post-LT outcomes, increase available DCD grafts ⚖️ viability criteria heterogeneous due to rapid adoption in different countries (w different laws) + may depend on associated technologies (ie ex-situ MP) 🧪current viability criteria on NRP = mainly macroscopic aspect, lactate clearance, transaminases levels (cholangiocellular parameters not widely used), but no definitive cut-off values can be established ⏰despite long term favourable results, use of extended NRP viability criteria may lead to prolonged vasoplegia + severe PRS 🔥damage, inflammatory, regeneration markers should be investigated as predictive of viable liver grafts

📢 Train the Trainers ECMO: to prepare #ECMO educators to design, deliver, evaluate high-quality, simulation-based training in accordance with ELSO educational standards 🎯Target: ECMOlogists min 5-7y experience in #ECLS 📆 15-17 July 2026 📌 Barcelona 📫gestio@aulavallhebron.cat

Please join our webinar on April 13th 2-3pm EST: “Viability Criteria for Liver NRP” Speaker: Davide Ghinolfi MD, PhD Moderators: Paulo Martins MD PhD Charles Strom MD Aleah Brubaker MD PhD To register: us06web.zoom.us/webinar/regist… @AST_LICOP @ASTSChimera @IHPBA @ISOPPT

🫀 🫁 Parallel dual-lumen VV #ECMO post #ECPR? Strategy to address severe differential oxygenation complicating extracorporeal #resuscitation. This approach offers an alternative to hybrid V-AV ECMO, if respiratory failure occurs. Decision to escalate #ECLS to facilitate neuroprotection should follow multidisciplinary consultation in experienced services, with appropriate timing and care taken. @asaiojournal 🖇️ bit.ly/4tDvH3i