Frank

Why

Bruuuuuuh!

I Google everything I don’t know or understand. Words, phrases, scriptures, lyrics, news articles. There is absolutely no shame in educating yourself.

mom was right, it is that damn phone

Farming is a game of muscle!

Riiiight

Mental illness has just been traced to a single gene for the first time. For decades, mental illnesses like schizophrenia were believed to arise from the complex interplay of numerous genes and environmental factors. Now, a groundbreaking study has identified the first single gene capable of triggering psychiatric disorders entirely on its own. Researchers have pinpointed GRIN2A as this rare culprit. In some individuals carrying specific damaging variants of the gene, severe psychiatric conditions – including schizophrenia-like symptoms – can emerge as early as childhood, rather than the typical onset in late adolescence or early adulthood. Perhaps most strikingly, several patients exhibited purely psychiatric symptoms with no trace of the seizures, intellectual disability, or developmental delays that were previously considered hallmarks of GRIN2A-related disorders. This finding dramatically reframes our understanding of how genetic mutations can lead to mental illness. GRIN2A encodes part of the brain’s NMDA receptors, which are critical for communication between neurons. When the gene is faulty, it throws this signaling system into disarray. Encouragingly, some affected individuals showed clear improvement when given L-serine, an inexpensive amino acid supplement that helps restore NMDA receptor function. Though still in its early stages, the discovery raises the prospect of genuinely precision-based treatments for certain forms of mental illness – therapies that correct the root genetic cause rather than merely managing symptoms. The results come from the world’s largest registry of GRIN2A patients and represent more than ten years of close collaboration between neurologists, psychiatrists, and geneticists across the globe. ["GRIN2A null variants confer a high risk for early-onset schizophrenia and other mental disorders and potentially enable precision therapy." Molecular Psychiatry, 2025]

👏 !

Why Farmers in China Dry Tomatoes Like This 🤯

Is it just me, or does anyone else need the first hour of work to be completely quiet. no meetings, no coworkers talking, just peace?

Bruh I watched this video on the edge of my seat... one wrong move nje!

Nikhuluma amasimba la online during high unemployment rate pham-kwam-front-kwa-bantu!

I love learning g about ancient ways of life

British guys still drive the old one

All i know is that I need to go there

You gonna hear All I Do Is Win out there my brother, re mo Mzansi mo. Stay indoors and stay toasty.

After 25 years of research, Brazilian scientists developed a drug capable of regenerating spinal cord tissue after severe injuries. The therapy stimulates axon regrowth and reduces scarring that typically prevents nerve recovery. In preclinical trials, treated animals regained partial motor function within weeks. The drug combines neurotrophic factors, small molecule compounds, and bio-scaffolds to guide nerve repair. Human trials are now underway to assess safety and effectiveness. If successful, this breakthrough could restore mobility to millions, transform rehabilitation medicine, and reduce long-term dependency on care. It also sets the stage for future therapies combining cellular engineering and regenerative biology to treat other complex injuries.

The richest African sells commodities. You are overthinking yourself to the gutter.

Haha... you are part of the problem why the coal was wet

The older you get the more you realize jeans are a terrible piece of clothing