GAMGEE

i am scaling the work i did for Rose through a company today we launch Gamgee: software to design personalised cancer treatments for dogs gamgee.io

@paul_conyngham It started with one dog, but we are just getting started!

A lot of you found me through Rosie's story. What I didn't say then: I never intended to stop at one dog. Rosie's case proved something. A personalized mRNA cancer vaccine could teach her immune system to fight cancer We started Gamgee. Same approach, built to run for any dog.

I just sequenced a human genome to 30× coverage entirely at home. As far as I know, this is the first time this has been done. I didn’t step foot in a lab once. Every step - from saliva collection, to running the sequencer - took place in a single room with a dining table + kitchenette. Six weeks ago, I had never done wet lab biology before. I used an Oxford Nanopore P2 Solo - the only commercially available sequencing device portable enough to do 30x human genome sequencing at home. Biggest takeaway - I could build something that combined software, hardware, and molecular biology far faster than I thought was possible. I can name >100 specific instances where AI helped me solve a technical problem that would previously have blocked me because I lacked access to a domain expert. For example: how do I save my sequencing run when my DNA extraction yield is 4x lower than I need it to be, and I have this limited set of reagents to hand? To make this work, I had to navigate multiple disciplines: - writing software to monitor sequencing runs and orchestrate remote GPU infra for basecalling - learning + executing 5 hour long molecular biology protocols - building a hardware device to quantify DNA concentration Apologies for the hyperbole, but I feel super lucky to be living in 2026. A few weeks ago I decided to sequence a human genome to 30x at home. Then I actually did it. And I did it really quickly.

Big News Coming from GAMGEE in the coming days, Follow us here @gamgeetechnologiesinc" target="_blank" rel="nofollow noopener">substack.com/@gamgeetechnol…