George Thompson

We must consider fungal diseases in patients with suspected TB relapse. It seems obvious. But it is not.

🔥🗞️Olorofim for the treatment of invasive fungal diseases in patients with few or no therapeutic options: a single-arm, open-label, phase 2b study. Groundbreaking work on a very promising new antifungal. Free access here: authors.elsevier.com/c/1lHca5E-UokK…

Perspective by George R. Thompson III, MD (@GRThompsonMD), and Angel N. Desai, MD, MPH: Addressing Antifungal Drug Resistance — A “One Health–One World” Challenge nej.md/4kMyVOd #GlobalHealth

@SolidEvidence How do you know with certainty it’s a human carrier? Could be domestic pet?

Maryland folks, I need another favor. There is a person from Anne Arundel county that has been infected with SARS-CoV-2 for about 3 years (Delta infection). They probably don’t even know they are infected, but they are shedding a ton of viral material in wastewater 1/

@DrLuisO Haha. They are like bad attempts at haikus!

The @FlemingCentre billboard in NYC's Times Square is very cool! Well worth checking out if you are in the area! every11seconds.com #StopSuperbugs #AMRSOS ⚕️ #FireExtinguishersOfMedicine

@IdVilchez @BradSpellberg @DrToddLee @wwrighID I’ll play, Kingella kingae

#IDtwitter #IDxpost haven't seen this foe in a while. Would you use your name to label a new discovered bacteria? In honor of Elizabeth King who initially discovered Flavobacterium meningosepticum. What other bacteria was named after her? @BradSpellberg @DrToddLee @wwrighID

@tannerfreiburg @WGEM Unlike - is there a downvote button. We have probably approached DSM5 cat to people ratio criteria for something

@WGEM @GRThompsonMD you could probably use a few more cats.

The Animal Protective Association of Missouri is asking for help after taking in more than 137 cats from that single hoarding case, pushing its feline population to nearly 500. on.wgem.com/4ggLCP6

@boulware_dr @DrNeilStone @FungalDoc @ApuAkkad1 @GermHunterMD Exactly

#IDtwitter Anecdotally, have been seeing a lot of intolerance and adverse effects of long term (> 3 months) fluconazole (400mg or higher). Others with similar or different experiences? If so- alternatives for crypto, cocci treatment most specifically? @FungalDoc @GermHunterMD @GRThompsonMD @TxID_Fellows

@DrNeilStone @FungalDoc @ApuAkkad1 @GermHunterMD I think of it like trying on shoes. Supposed to fit- but sometimes don’t

@FungalDoc @ApuAkkad1 @GermHunterMD Intolerance to one azole does not mean intolerance to all. Sometimes my patients do the "azole dance" trying all the different azoles until we can find one they tolerate. Isavuconazole an option if accessible/affordable.

Congratulations to Hannah, Derek and @microbe_enjoyer for our first venture into Candida pathogenesis nam12.safelinks.protection.outlook.com/?url=https%3A%…

New CDC MMWR report: Essentially genetically identical Mycobacterium abscessus subspecies massilienseinfections following stem cell injections at different clinics in Mexico prompted an outbreak investigation. bit.ly/mm7318a3 @MattDavis138 @GRThompsonMD

@tony_breu It’s in process- ncbi.nlm.nih.gov/pmc/articles/P…

1/ Why hasn’t group A strep (GAS) developed resistance to penicillin? This is particularly odd given that other closely related gram-positive species (e.g., Strep pneumoniae) have resistant strains. Given the global burden of disease, understanding GAS is essential...

@DrValleyFever @GRThompsonMD @hyphaltip @EduardoBagagli

@sanfordguide Is there an “age-up” option? Where our auto renewal comes with a slightly larger font every year?

Hot off the press, 2024 Sanford Guides are shipping out fast! We just completed all our auto-renewing book subscriptions and pre-orders. PRO TIP: Get your book first (and at a discount) by selecting 'auto-renewal' when you buy it. sanfordguide.com/products/print…

Prior to expanding Coccidioides prophylaxis, we performed a safety study to assess whether there were any serious adverse patient outcomes from use of fluconazole in our kidney transplant recipients. (1/5)🧵 academic.oup.com/mmy/advance-ar… #IDtwitter #TxID

@alan_koff @TxID_Fellows @jschaenman @DrAndreKalil @MichaelGIsonMD @NicoBarrosID @camwolfe Yeah I find it absurd we tell patients they can’t have flowers in their room, but we are ok w them inhaling dried vegetative material that is covered with fungi and bacteria in a non filtered way.

@GRThompsonMD @TxID_Fellows @jschaenman @DrAndreKalil @MichaelGIsonMD @NicoBarrosID @camwolfe It was about marijuana use in immunocompromised patients and how we should be counseling them.

10/ What counseling do you give surrounding marijuana in the pre and post-transplant period? Is there any safe marijuana use post-transplantation? Do you counsel them on medication interactions? #TxIDChat @jschaenman @DrAndreKalil @MichaelGIsonMD @NicoBarrosID @camwolfe

@alan_koff @TxID_Fellows @jschaenman @DrAndreKalil @MichaelGIsonMD @NicoBarrosID @camwolfe Maybe the original tweet was deleted? I can’t see anything above yours

@TxID_Fellows @jschaenman @DrAndreKalil @MichaelGIsonMD @NicoBarrosID @camwolfe @GRThompsonMD

@PradGeorge @nickmmark It’s in an old paper. But they were tying off bronchi in murine models. That is post obstructive pneumonia though- not atelectasis. That’s where originated though.

@nickmmark Lore, Tradition, Old Surgeon tales…There was an Emiratis prof who trained in the 60’s talk about it being the common belief in his training days…we still have surgeons who prefer silk sutures…Blows the residents minds when I reframe silk as foreign protein made from 🪱 vomit

The most frustrating phenomena in the medical literature also has the cutest name: The Woozle Effect The Woozle Effect is when a source is widely cited for a claim it does not actually support, often at the end of a long chain of citations. What examples can you think of?

@DrPHO_ID @PaulSaxMD Sort of what I was thinking. Cardiology reads a hundred ekgs in an hour (some done a day or two prior and thus no clinical impact but they can bill for the read). Seems we should be able to bill for a micro culture result read….or HIV suscept

@GRThompsonMD @PaulSaxMD Oh interesting, so like for everything positive culture, there might be something like this?

Query for ID docs practicing here in the USA: Who uses these "interprofessional consults codes" for curbsides/eConsults? The RVUs are not great for reimbursement, and needing patient consent must be difficult. aan.com/siteassets/hom…