Nathan Pearson

18.4K posts

Nathan Pearson

Nathan Pearson

@GenomeNathan

Human, genomicist. Ok, human genomicist...bringing DNA to life, for good, for science, for free, at https://t.co/f49Ew06307.

Earth Katılım Nisan 2012
1.3K Takip Edilen7.4K Takipçiler
Nathan Pearson
Nathan Pearson@GenomeNathan·
@knockinthenight @dwarkesh_sp You've qualified this claim with so many subjectives ('meaningfully', 'broad', 'much more', 'massively') as to make it unfalsifiable. But we human geneticists have long *presumed* strongly spacetime-varied adaptation to pathogens/climate/diet (themselves entangled), etc.
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Olimade Tarsus ⚛️
Olimade Tarsus ⚛️@knockinthenight·
@GenomeNathan @dwarkesh_sp I don’t disagree with you, however, selective pressures meaningfully differentiated by environment on a broad scale in distribution of alleles disposing much more than skin colour is massively controversial, especially without the idea that adaptation sped up given timescales
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Dwarkesh Patel
Dwarkesh Patel@dwarkesh_sp·
David Reich is back. He and collaborator Ali Akbari just published a paper that overturns a long-standing consensus about human evolution — that natural selection has been dormant in our species since the agricultural revolution. By scaling ancient DNA sequencing and developing a new statistical method, they found that selection has actually sped up. Selection went especially bonkers during the Bronze Age (around 3,000 years ago). That's when gene frequencies for everything from immune function to body fat to intelligence were most in flux. Over the last 10,000 years, selection pushed the genetic predictor of cognitive performance up by roughly a full standard deviation — most of it between 4,000 and 2,000 years ago. After we finished recording, David sketched out on a whiteboard his new heretical model about who the Neanderthals really were. Luckily, I took out my iPhone and managed to record it. He thinks the standard story (that Neanderthals are some separate archaic lineage we interbred with a little) just doesn't fit the evidence. Instead, he proposes that Neanderthals are essentially genetically-swamped modern humans. A small population somewhere around the Caucasus invented Middle Stone Age technology roughly 300,000 years ago and expanded outward. The ones that moved into Europe interbred with local archaic humans, got genetically swamped, and became Neanderthals. The same expansion went into Africa, met much more diverged archaic Africans, and that mixture became us. This means Neanderthals and modern humans share the same cultural ancestry — the only difference is which archaic humans they mixed with afterward. David is a brilliant and rigorous scholar. It was a real delight to learn from him again. 0:00:00 – Ancient DNA suggests strong selection over last 10,000 years 0:16:24 – Natural selection intensified during the Bronze Age 0:35:40 – Why didn't evolution max out intelligence? 0:58:00 – Evolution is limited by time, not population size 1:09:40 – Why no farming before the Ice Age? 1:17:52 – The Neanderthal puzzle David can’t stop thinking about 1:54:40 – The methodology behind this breakthrough
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Nathan Pearson
Nathan Pearson@GenomeNathan·
@DidiMatityahu @_ZachFoster @TaliaRinger No, I responded with clear counterexamples, and with a reminder that without Jewish-exceptionalist circularity you're then declaring anyone acknowledging Copt or Mandaean identity as more than 'just a religion' must be [checks notes] Zionist and/or Nazi.
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Didi Matityahu
Didi Matityahu@DidiMatityahu·
@GenomeNathan @_ZachFoster @TaliaRinger Instead of responding to the point, you send me to ask someone else about irrelevant groups. I don't define 'Jewish', Judaism does that. You want to use the same word while ignoring the source so again - only Zionism and Nazism.
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Nathan Pearson
Nathan Pearson@GenomeNathan·
@DidiMatityahu @_ZachFoster @TaliaRinger 1. Go ask. Though apparently you'll circularly define their answers as 'zionist' or not by whether they agree w/me. 2. No, *you* circularly define 'Jewish' as 'a religion'; the counterexamples (incl. my & many others' existence as non-religious [group X] members) debunk that.
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Didi Matityahu
Didi Matityahu@DidiMatityahu·
@GenomeNathan @_ZachFoster @TaliaRinger "Ask any anthropologist" - Appeal to authority "Assyrian, Copt, Mandaean, Samaritan, etc" - Strawman argument. These are not religions. What I wrote is a fact so instead of reflecting, you have to use logical fallacies.
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Nathan Pearson
Nathan Pearson@GenomeNathan·
@DidiMatityahu @_ZachFoster @TaliaRinger Again, flatly false, however enamored you are of your silly, pointless theory. Ask any anthropologist if Assyrian, Copt, Mandaean, Samaritan, etc. identities (let alone those of peoples farther from Palestine) are 'just religions' — or at all entail statist/other supremacism.
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Didi Matityahu
Didi Matityahu@DidiMatityahu·
@GenomeNathan @_ZachFoster @TaliaRinger The only ideologies that consider "Jew" as "not just a religion" are Zionism and Nazism. Nazism is allegedly gone, but some people, including Jews, insist on maintaining the same ideology.
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Didi Matityahu
Didi Matityahu@DidiMatityahu·
@GenomeNathan @_ZachFoster @TaliaRinger There is a perfect correlation between Zionists and those who believe that "Jew" is an ethnic group, it is the fundamental lie that enabled Zionism, the essence of it.
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Nathan Pearson
Nathan Pearson@GenomeNathan·
@DidiMatityahu @_ZachFoster @TaliaRinger No, you have it backward. Setting aside rife *religious* supremacism, grasping that ancestors' religion drove cultural (even genetic) differentiation, or vice versa, doesn't entail any right to rule others anywhere. Cf. many other groups sans statist/supremacist movements.
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Didi Matityahu
Didi Matityahu@DidiMatityahu·
@GenomeNathan @_ZachFoster @TaliaRinger No, you don't. You need Zionism in order to believe that you are a Jew by race or whatever it is instead of religion. You hate Zionism like Israeli-liberals hate Netanyahu - a scapegoat to compensate for the dissonance.
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Nathan Pearson
Nathan Pearson@GenomeNathan·
@_ZachFoster @TaliaRinger Zach, non-religious antizionist Jew here. Ethnicity and culture can, and do, transcend not just genes but also particular beliefs. And one needn't reduce Jewishness to religion to staunchly and vigorously oppose zionism (or indeed any form of Jewish-supremacism).
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Zachary Foster
Zachary Foster@_ZachFoster·
The Jewish-Zionist obsession with being more than "just a religion" is a strange pathology. As if being a religion is a problem. As if Jewish converts undergo a DNA transfusion when they convert. As if black Jews, brown Jews & white Jews have shared common ancestry. As if shared values, rituals, & traditions are inferior than having shared blood. If only Jews thought more like the Nazis! Sincereley, -Zionism
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Nathan Pearson
Nathan Pearson@GenomeNathan·
@The_Yokay Palestinian families are indeed the long-resident native majority of Israel. But yes, we (like Jackson and Geyer) clearly grasp that having a settler-supremacist state in the first place requires subjugating, exiling, or/and attritionally genociding such native majority.
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Yokay 📯 💫🎗 🍌
Yokay 📯 💫🎗 🍌@The_Yokay·
@GenomeNathan Palestinian Arabs are not Israel's native majority. For good reason. There would be no Israel. And I suppose that half of the world's Jewry will not take the risk of annihilation for the sake of some lofty idea that white American slaveholding colonialist claim they're upholding.
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Nathan Pearson
Nathan Pearson@GenomeNathan·
@The_Yokay Uh, no. As noted, Israel does indeed bar its native majority from voting majority.
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Nathan Pearson
Nathan Pearson@GenomeNathan·
@josemaforts22 @carolinadayan1 Palestinians are c/s Levantines who (as al-Maqdisi) so identify. Like *most* human groups (Kurd, Romaniote, Sotho, Vlach, Zuni...), they won't appear in your consumer DNA results, for sundry reasons: company panel omits them, groups them w/others, or shows scant match to you.
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Carolina Dayan
Carolina Dayan@carolinadayan1·
Queria que me agilizassem uma resposta. O que é um Palestino? Por que Palestino não é uma categoria presente em nenhum teste de ancestralidade? Aguardando…
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Nathan Pearson
Nathan Pearson@GenomeNathan·
@kthalps Katie, note that the last signers were actually Irma & Stefan Wolpe (not Wolfe)...presumedly distant patrilineal cousins to South African ANC stalwart Harold Wolpe.
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Katie Halper
Katie Halper@kthalps·
I’m sorry, but you don’t get to lecture anyone about how they misrepresented Einstein’s relationship with Israel if your alleged corrective omits that he compared the party that turned into Likkud to Nazis.
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Nathan Pearson
Nathan Pearson@GenomeNathan·
@LibyaLiberty @KR3Wmatic It's a great question — and, of course, applies equally well to any notional creator of such matter. And especially one not just notionally invisible and relatably intellligent/otherwise characteristic of human social imagination, but immortal too.
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Hend Amry
Hend Amry@LibyaLiberty·
@KR3Wmatic Matter can neither be created nor destroyed. Where did it come from.
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Yẹmí
Yẹmí@KR3Wmatic·
My atheist daughter asked me to prove God's existence. What do I tell her? She is 19.
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Michael Rosen 💙💙🎓🎓 NICE 爷爷
@VividProwess Pretty well most of it is Canaan and it precedes any Jewish kingdom. People like you, interested in historical origins will want to join me in re-establishing the city-states of Canaan and, like me, be a Canaanist. I propose a Canaanite federation of city-states. Join me.
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Vivid.🇮🇱
Vivid.🇮🇱@VividProwess·
All of it is Israel. There was never a "Palestinian" state.
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