How does delirium disrupt so many brain functions? Widespread network dysfunction in delirium demonstrated on FDG-PET scans. doi.org/10.1002/alz.70…
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Gideon Caplan
536 posts
Exciting FIRST result of new treatment for delirium! Long-acting intranasal insulin for the treatment of delirium—a randomised clinical trial academic.oup.com/ageing/article… @ANZDA_delirium @AmerDelirium @EDA_delirium @LADIG_Delirium
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Gideon Caplan retweetledi
Preop plasma concentrations of p-tau181, p-tau231, and p-tau217 predicted the occurrence & severity of postop #delirium in older adults having laparoscopic surgery
P-tau231 had the highest predictive value
🔗 doi.org/10.1093/gerona…
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Gideon Caplan retweetledi
Gideon Caplan retweetledi
Raising #delirium one coffee at a time. Thanks Danny for being a great sport and allowing us to camp out at Good Chat #WDAD2025
Eamonn Eeles@EelesEamonn
Happy #WDAD2025 from Brizzie from @andyteodorczuk @EelesEamonn. Is the full caffeination and a ‘Good Chat’ a delirium prevention strategy?
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Gideon Caplan retweetledi
@A_MacLullich @andyteodorczuk @RANZCP @AmerDelirium @ProfLizSampson @adamgordon1978 @GideonCaplan @deliriumkrish @NIDUS_Delirium @iDelirium_Aware @anzsgm @rcpsychOldAge @GeriSoc #WDAD2025
AustralasianDelirium@ANZDA_delirium
#WDAD2025 from sunny Cairns and colourful convener of #DECLARED2025 @ajjuss
QME
@AndersFjell @MarkOldhamMD @LCBC_UiO @LifebrainEU @UiO_LifeSci Head size trumps education. Another win for phrenology!
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Preprint: Using 400k memory tests & 15k brain MRIs, we find no evidence that education enhances cognitive reserve. Edu linearly related to better mem, but not less brain or cogn decline, or more tolerance to atrophy 🧵@LCBC_UiO @LifebrainEU @UiO_LifeSci
medrxiv.org/content/10.110…
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Gideon Caplan retweetledi
Very informative study from Australia detailing staff experiences of caring for patients with #delirium
Stark findings - delirium seen as uninteresting, unimportant and emotionally challenging. The need to support staff is clear as is to increase education pubmed.ncbi.nlm.nih.gov/39078153/
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Gideon Caplan retweetledi
@anita_nitch overview on the current & emerging drug therapies 4 managing #delirium #HunterGeriatrics2024 @CityNewcastle view on her PhD project long-acting nasal insulin 4 Rx tinyurl.com/y32dum6n @meera_agar @JacquiCTClose @GideonCaplan tinyurl.com/7394bj2n @A_MacLullich
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Gideon Caplan retweetledi
Gideon Caplan retweetledi
Gideon Caplan retweetledi
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Also doi.org/10.2217/174550… for review of topic and work by @DrMqAgMas
Gideon Caplan@GideonCaplan
Does home treatment affect delirium? A randomised controlled trial of rehabilitation of elderly and care at home or usual treatment (The REACH-OUT trial) academic.oup.com/ageing/article… shows prevalence of delirium in HITH vs in hospital.
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Does home treatment affect delirium? A randomised controlled trial of rehabilitation of elderly and care at home or usual treatment (The REACH-OUT trial) academic.oup.com/ageing/article… shows prevalence of delirium in HITH vs in hospital.
Peter Lange@drpeterlange
@A_MacLullich @sharon_inouye @GideonCaplan #delirium I'm looking for evidence of delirium prevalence in Hospital in the Home programs, is there any?
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CSF Tissue Inhibitors of Metalloproteinases and their role in delirium communities.springernature.com/posts/mmps-and…
@lowatne @mariaksnes @beneerland
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Gideon Caplan retweetledi
"Studies of how quickly doctors interrupt patients find that the median time is 11 seconds. Nobody feels listened to in 11 seconds."
@Richard56 discusses the healing power of being listened to
bmj.com/content/385/bm…
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Gideon Caplan retweetledi
📢Check out our new paper in @CommsMedicine linking metalloproteinases and their tissue inhibitors to #delirium🧠@lowatne @asjdseesit @UniOslo_MED @Ahus_no 🧵
nature.com/articles/s4385…
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Gideon Caplan retweetledi
Many, many congratulations to Prof Jacqui Close AM for being made a Member of the
Order of Australia! A very well deserved recognition for all the tremendous work she’s done improving care for older Australians. @JacquiCTClose @anzsgm @DrRobOSullivan
Cairns, Queensland 🇦🇺 English