

Snap-Trapping Strategy for Amine-Specific Bioconjugation with Pyridotriazole Carbaldehydes | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/ja…
Gong Chen
66 posts

@GongChenLab
C-H bonds, peptides, carbohydrates


Snap-Trapping Strategy for Amine-Specific Bioconjugation with Pyridotriazole Carbaldehydes | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/ja…


@gongchenlab have been hunting for ways to crosslink two different amines for conjugation: turns out that just a drop of CS₂ in air delivers great results! Read on in their Research Article: • onlinelibrary.wiley.com/doi/10.1002/an…

Special Issue alert! 🚨 This one is truly •radical• pubs.acs.org/page/orlef7/vs… This VSI highlights the state of the art in radical reaction development and the strategic incorporation of radical reactions in the construction and modification of important molecules.

Copper-Mediated Cyclization Gives 5-Trifluoromethylpyrroles: Practical approach uses CF3-imidoyl sulfoxonium ylides and terminal alkynes chemistryviews.org/copper-mediate…


Peptide Stapling by Crosslinking Two Amines with alpha-Ketoaldehydes through Diverse Modified Glyoxal-Lysine Dimer Linkers (Gong Chen and co-workers) @NKU1919 onlinelibrary.wiley.com/doi/10.1002/an…


N-glycoside synthesis, a tough nut to crack, is now approachable with our new light/Cu catalysis method, allowing N-glycosidic bond formation under mild conditions with exceptional water tolerance and unique chemoselectivity. Another fruitful collaboration with MJ Koh @MJKoh87.

Now online: Article by @MJKoh87 @GongChenLab and co-workers @NKU1919 @ChemNUS N-glycoside synthesis through combined copper- and photoredox-catalysed N-glycosylation of N-nucleophiles nature.com/articles/s4416… ($)

Formaldehyde-Mediated Hydride Liberation of Alkylamines for Intermolecular Reactions in Hexafluoroisopropanol @J_A_C_S #Chemistry #Chemed #Science pubs.acs.org/doi/10.1021/ja…






We are thrilled to announce that Prof. Gong Chen of Nankai University will be joining #OrgLett as an Associate Editor on December 1. Known for his work on metal-catalyzed C-H functionalization and on peptides and oligosaccharides, Gong may soon be handling your manuscript!

SESSION 9: INNOVATIONS IN PEPTIDE AND PROTEIN CHEMISTRY begins with Gong Chen from Nankai University presenting "New Methods for Construction of Complex Peptide Macrocycles" #Peptides2022






