Lenhard group

23 posts

Lenhard group

Lenhard group

@GroupLenhard

We are a computational group based in the @MRC_LMS at Imperial College London @imperialcollege. Our research revolves around computational genomics

London, England Katılım Nisan 2017
113 Takip Edilen164 Takipçiler
Lenhard group retweetledi
Sarvesh Nikumbh
Sarvesh Nikumbh@sarveshnikumbh·
🥳🥳 SeqArchR is now available online in PLOS Comp Biol doi.org/10.1371/journa… - Give the article a read - Use seqArchR Bioconductor pkg - Appreciate simple but powerful NMF - Share feedback - Spread the knowledge 🙂🙂 @BorisLenhard @GroupLenhard @MRC_LMS @imperialcollege
Sarvesh Nikumbh@sarveshnikumbh

Happy to introduce *seqArchR*, an approach using non-negative matrix factorisation (NMF) for de novo identification of promoter sequence architectures. 1/7 biorxiv.org/content/10.110…

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Lenhard group
Lenhard group@GroupLenhard·
DNA methylation and obesity --- do you expect an association between them? Yes! See QT below Impressive efforts by @CroBeaver with other joint first authors in this study led by William Scott, Genomics of Obesity group @MRCLMS Huge congrats @CroBeaver @BorisLenhard
Damir Baranašić@CroBeaver

Exciting collaboration within @MRC_LMS, led by the Genomics of Obesity group with @GroupLenhard, and @BorisLenhard, reveals the role of DNA methylation in obesity and diabetes in a groundbreaking study in @NatureComms. Check it out: nature.com/articles/s4146… #ObesityResearch 1/8 🧵

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Lenhard group retweetledi
Boris Lenhard
Boris Lenhard@BorisLenhard·
A new preprint from our group, describing a tool for clustering promoters based on they key architectural elements and putting it to work to study some nice examples of time-dependent differential use of promoter classes.
Sarvesh Nikumbh@sarveshnikumbh

Happy to introduce *seqArchR*, an approach using non-negative matrix factorisation (NMF) for de novo identification of promoter sequence architectures. 1/7 biorxiv.org/content/10.110…

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Lenhard group retweetledi
DANIO-CODE
DANIO-CODE@daniocode·
The comprehensive atlas of developmental regulatory elements in zebrafish is published today in @NatureGenet nature.com/articles/s4158…. In addition to the BioRxiv submission twitter.com/daniocode/stat… in this paper we added further resources and results. (1/n)
DANIO-CODE tweet mediaDANIO-CODE tweet media
DANIO-CODE@daniocode

DANIO-CODE is proud to share our findings and a huge multi-genomics resource on the regulatory elements in the development of #zebrafish. We analyzed 1,802 previously (un)published sequencing data sets across 38 developing stages and 21 assay types. (1/n) biorxiv.org/content/10.110…

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Lenhard group retweetledi
Damir Baranašić
Damir Baranašić@CroBeaver·
I am happy and proud that our DANIO-CODE @daniocode paper is finally out in Nature Genetics @NatureGenet! I wish to say thank you to everyone who helped and supported our work up until now, with the hope we can continue to deliver in the future as well! nature.com/articles/s4158…
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Lenhard group retweetledi
Boris Lenhard
Boris Lenhard@BorisLenhard·
A PhD student position in computational genomics at Imperial, jointly supervised by Matthias Merkenschlager and me: findaphd.com/search/Project…
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Keşfet

@BorisLenhard @MRC_LMS @imperialcollege @CroBeaver @MRCLMS @radinagg @PiotrBalwierz @FabioDorazio