Mads I. Blücher
10.7K posts












SLEEP 101








First look at Netflix’s live-action ‘SCOOBY-DOO: ORIGINS.’ Now in production.






Salt has been blamed as the culprit for damaging your arteries. A new mouse study puts salt-sensitive hypertension in context. Salt doesn't do it directly, it triggers your immune system to do it. 4 weeks on a high-salt diet (8% NaCl) cut vasodilation by over 20% and spiked senescence markers in blood vessel walls. Pure NaCl did nothing to endothelial cells. The immune cytokine IL-16 alone replicated the full damage. The senolytic (navitoclax) reversed it. Vascular function restored, likely via nitric oxide. The mechanism behind salt-sensitive hypertension may be the immune response salt provokes, and the senescent cells that response leaves behind.




