Sandeep Gupta

First lab meeting of the Gupta lab. very exciting start! We are building functional stem cell models to investigate neurodevelopmental disorders like autism

For the first time, UCLA scientists @LTULab have mapped how Down syndrome reshapes the human brain before birth — uncovering surprising shifts in neuron development that may explain differences in brain size and cognition. Read more ➡️bit.ly/4ebcP7z #BrainDevelopment

Several staff scientist positions available in our lab at Stanford More details and application at the link below

Check out our new publication at rdcu.be/fbd7o on Developmental organization of sensory and sympathetic ganglia, by @HarryKiv @shishenyxx and amazing collaborators.

Transcriptomic and spatial organization of mouse spinal cord projection neurons dlvr.it/TQCtxn

Science often chases buzzwords, but studying sex determination showed me how a simple question can reveal deep biology. Discovering Zelda’s role was thrilling. Grateful to Erika Bach, my colleagues, and Artyom Kopp for the beautiful primer.journals.plos.org/plosbiology/ar…

@Sneh_Harsh Woohoo what a beautiful work, many congratulations!!

3️⃣ weeks, 2️⃣ projects - this @Cajal_Training program provides hands-on experience in molecular, cellular & behavioral #neuroscience. 👉 Applications close on 7 Jan - apply now! ibro.org/training-oppor… #IBROinAsiaPacific #IBROinUSCanada #IBROinAfrica #IBROinLatAm #IBROinEurope

Fantastic talks at #CMMDR2026. Fun to see excellent science of regeneration in diverse model systems! Plus seeing my graduate lab's students giving talks is a surreal moment!

In our most recent publication in @NatureProtocols, we outline detailed methods for performing CRISPR screens in human neural #organoids and #assembloids. The integration of these screening approaches with human models is becoming increasingly powerful for uncovering human biology and gaining mechanistic insights into disease. This is the 4th article in our series of detailed protocols describing the generation of regionalized neural organoids and of assembloids, and their transplantation, and it serves as a foundation for our hands-on course in our Stanford @BrOrganogenesis. Work led by XiangLing Meng (now running her own lab at Baylor) with Noah Reiss!

Welcome back to #ScienceJobsTuesday, a weekly thread where we bring a curated list of jobs, grants, and events relevant to the Indian life science community 👩‍🔬 @DBTIndia @IndiaDST @India_Alliance @serbonline

The power of the media: core culture conditions direct gastruloid development This Research Highlight showcases the work from Tina Balayo, André Dias (@_andre_Dias_ ), David Turner (@da40cambs) and colleagues: journals.biologists.com/dev/article/15…

Spatial and single-cell transcriptomics reveal the reorganization of cerebellar microglia with aging dlvr.it/TPVbQW

Comparative whole-brain and single-cell analyses are identifying neurons orchestrating neurological functions. Learn more in a new #SciencePerspective: scim.ag/3WMwLDR

are we the only one on X? its been very fun first day of SCN so far, antelar regeneration to myelinoids! #TMM2025

Online Now! A phenotypic brain organoid atlas and biobank for neurodevelopmental disorders dlvr.it/TP3CkX #stemcells

We are grateful for the support our partner, @StolleryKids, provides to advance children's and perinatal research! 💚💙

that's awesome!

Failure of roof plate invagination (RPI)= holoprosencephaly. What r the forces & molecular mechanisms lead to RPI: differential cell proliferation & thickness. Simulations suggest both needed+ differential stiffness (seen exptly too) @sen_jonaki @IITKanpur #IAN25 @IndAcadNeurosci

The mutations in brain cells induced by recurrent head injury and chronic traumatic encephalopathy (CTE) are different @ScienceMagazine science.org/doi/10.1126/sc…

This is what the last five years have been about! Incredibly proud to share our new paper in Nature Genetics: “Transcription Factor Switching Drives Subtype Specific Pancreatic Cancer.” Thank you @JCarrollLab @PancreaticCanUK @CRUK_CI nature.com/articles/s4158…