Hari Venugopal

86 posts

Hari Venugopal

@HariVenugopal2

Senior Microscopist @CryoEM_Monash

Katılım Nisan 2021

106 Takip Edilen209 Takipçiler

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Hari Venugopal@HariVenugopal2·11 Eki

Our 1.52 Å resolution #cryoEM structure of the mycobacterial hydrogenase Huc. An extremely fruitful collaboration with @Rhys__G and @greeninglab. Data collected on G1 Titan Krios(300 kV), S-FEG, K3 camera post GIF(Bioquantum) and ZLF with a slit width of 10eV @CryoEM_Monash.

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Hari Venugopal@HariVenugopal2·10 Oca

Another amazing #cryoem story from @LuptonCJ @bj_charles and Andrew Ellisdon lab.

Charles Bayly-Jones@bj_charles

Absolutely thrilled to see our latest study online @CellCellPress. Structure of the lysosomal KICSTOR-GATOR1-SAMTOR nutrient-sensing supercomplex. doi.org/10.1016/j.cell… @LuptonCJ @Dr_MLHalls & Andrew Ellisdon. #cryoEM #KICSTOR #mTORC1 #GATOR1

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Hari Venugopal@HariVenugopal2·15 Eyl

Awesome work @OliBClarke .

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Winnie Tan@winn5tan·2 Tem

Excited to share our MORC2 paper out in @NatureComms! Feel free to read the open access version here — rdcu.be/euihg

Winnie Tan@winn5tan

Excited to share the 1st preprint from @ShabihShakeel lab @WEHI_research on oncoprotein MORC2 that is now available on bioRxiv! Here’s a thread on our main findings on how MORC2 phosphorylation influences DNA compaction and its implications in cancer🔬📜 biorxiv.org/content/10.110…

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Hari Venugopal@HariVenugopal2·31 May

Another awesome collaboration with @Rhys__G lab. Check out our latest high resolution cryo-EM work, ~70kDa membrane protein. Imaging done at @CryoEM_Monash

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Eric Hanssen@big_french_man·2 Şub

Do you want to know if you have what it takes to work in a large centralised EM platform, short stint just to see ! come and join us ⁦@Bio21Institute⁩ ⁦@UniMelb⁩ : Research Fellow in Electron Cryo Microscopy (Part-time) : jobs.unimelb.edu.au/en/job/919320/…

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Membrane Protein PDB@MemProtPDB·27 Oca

Resolving native GABAA receptor structures from the human brain | Nature doi.org/10.1038/s41586…

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Gatan Microscopy@GatanMicroscopy·22 Oca

High-resolution cryo-EM using a common LaB6 120-keV electron microscope equipped with the Alpine camera, a sub–200-keV direct electron detector from Gatan. Read about it today: ow.ly/4HiB50UKqfk #cryoEM #DirectDetection

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Membrane Protein PDB@MemProtPDB·6 Oca

High-resolution cryo-EM using a common LaB6 120-keV electron microscope equipped with a sub–200-keV direct electron detector | Science Advances science.org/doi/10.1126/sc…

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Hari Venugopal@HariVenugopal2·6 Oca

Thank you again to all the wonderful collaborators for their amazing samples and discussions. @JesseMobbs, @CyntiaTaveneau, @_danielfox, Ziva Vuckovic, @Rhys__G, @gavinjknott and @Thal_DM.

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Hari Venugopal@HariVenugopal2·6 Oca

Thrilled to see our work on high-resolution #cryoem using a common LaB6 120-keV TEM and sub–200-keV direct electron detector, now online @ScienceAdvances. science.org/doi/10.1126/sc… . A collaboration with @GatanMicroscopy, @GeorgRamm, and @CryoEM_Monash.

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Gavin Knott@gavinjknott·9 Ara

We are excited to share pre-prints describing a successful foray into ML-driven protein design. With @Rhys__G we designed proteins to potently inhibit CRISPR-Cas13 (doi.org/10.1101/2024.1…) or block heme piracy by pathogenic E. coli (doi.org/10.1101/2024.1…):

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Chris Lupton@LuptonCJ·3 Eki

Thrilled to see our work out in @Nature on the #cryoem structure of LYCHOS! A monumental effort from co-first author @bj_charles, the @Dr_Ellisdon Lab, the @Dr_MLHalls Lab from @MIPS_DDB, @HariVenugopal2 from @CryoEM_Monash. nature.com/articles/s4158…

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Charles Bayly-Jones@bj_charles·2 Eki

We are thrilled beyond words to see our LYCHOS (GPR155) publication out today in @Nature. 🥳 “LYCHOS is a human hybrid of a plant-like PIN transporter and a GPCR” nature.com/articles/s4158… 🧵

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Hari Venugopal@HariVenugopal2·10 Eyl

Check out these fantastic 100keV results from Thermos's Falcon C detector when imaged using a FEG source.

Abhay Kotecha@AbhayKot

Building on the work of Richard and Chris, here is our latest work showcasing the potential of the 100 keV #Tundra microscope with the Ceta F and Falcon C. We achieved high-resolution structures for a variety of protein complexes🧵.🔬#100keV #CryoEM. Movie by @lingboyu

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Structura Biotechnology@structurabio·30 Tem

Working on #cryoEM for membrane proteins? This new #CryoSPARC case study covers end to end advanced processing of a 73 kDa inactive state GPCR, including challenges and pitfalls, detailed figures and final maps. Read in full here: guide.cryosparc.com/processing-dat…

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Hari Venugopal@HariVenugopal2·12 Tem

In situ single-particle cryo-EM is picking up steam. Mind-blowing work!!!🤯

Yong Xiong Lab@Xiongosome

Our high-resolution (2.2 Å) in situ structural work reveals details of translational landscape, with various cofactors and antitumor drug/inhibitor, all directly within human cells! biorxiv.org/cgi/content/sh…

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Winnie Tan@winn5tan·29 Haz

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ARC CCeMMP@CCeMMP·28 Haz

Seminar alert! ⏰ The @arc_gov_au CCeMMP seminar series welcomes Ali Punjani (CEO, Structura Biotechnology Inc, Toronto, Canada) as our July speaker. Please join us & register here: ccemmp.org/events/ccemmp-… @structurabio @a_punjani

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Hari Venugopal@HariVenugopal2·21 Haz

@bluesocks81 Loved the name mate.

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Matthew Belousoff@bluesocks81·21 Haz

I'm super proud of my wife who just launched her website. She makes really nice polymer clay earrings. She did this all by herself with no prior experience. Check it out if your interested in hand crafted jewellery! olliepop.shop

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Guenter Resch@Nexperion·18 Haz

Last week's release of #SerialEM beta testing introduces "Multiple Grid Ops", an interface to auto acquire grid maps, square maps, and final data from multiple grids in a row using @thermosciEMSpec /@JEOLUSA autoloaders.

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Keşfet

@LuptonCJ @bj_charles @NatureComms @CryoEM_Monash @Bio21Institute @UniMelb @CyntiaTaveneau @_danielfox