Dr.Harsha Doddihal

All of us should live life fully understanding and digesting and 100% internalising the truth that there is a non-zero probability that we won't see tomorrow. We could die of a heart attack, get hit by a car, have a stroke in our sleep, it's a non-zero probability that today is your last day. In oncology lingo, I like to put it a different way: live like you're a patient with ALK+ metastatic lung cancer with your disease in remission on lorlatinib. You might live longer than your doctor (10+ year survivors are expected nowadays) or you might die tomorrow. Death is the final truth of life, it seems silly that most of us live life ignoring something that is 100% guaranteed to happen to all of us. If you accept your mortality as an inevitability, you will live a life with less regrets. When you know there is a non-zero chance of dying today, you will be less likely to live a life that is not true to yourself. Live life with no regrets.

This is a major story from #ASCO25. Randomized phase 3 trial of time of day of immunotherapy infusion. Randomized to infusion before or after 3pm. Early infusion far superior: PFS 11.3 vs 5.7 HR 0.42, OS HR 0.45! Impactful, pragmatic, not costly. This should be a bigger story.

⭐️Structured Exercise after Adjuvant Chemotherapy for Colon Cancer | New England Journal of Medicine @NEJM nejm.org/doi/full/10.10…

Amazing to see how such a simple structured exercise intervention can be a game changer in the management of colon cancer disease! Innovation doesn’t need to be expensive or fancy! Congratulations to #ChrisBooth and all involved in the #CHALLENGE study. #ASCO2025 @ASCO

Etymology & History Learning medium.com/p/etymology-hi…

Prediction of checkpoint inhibitor immunotherapy efficacy link.medium.com/CKrNBM3caRb

Insights from Eli Lilly’s CEO: Innovation, Culture, and the Future of Healthcare link.medium.com/IDuoXZtI8Qb

Diversity, Fast Learning & the Challenge of French Class link.medium.com/irGoROQ15Qb

People-Centred Care in Oncology link.medium.com/YFUaYLGXIQb

Conversation With ChatGPT link.medium.com/rMsu9poSzQb

Epigenetic Editing or Epi Editing link.medium.com/zUw2qx4E7Pb

China’s Leapfrog in New Drug Development link.medium.com/p2TqgBQprPb #Biotech #Innovation #DrugDevelopment #China #GlobalHealth

I just published India Emerges as Global Pharma’s Capability Centre Hub: A Look at the Driving Forces and Challenges link.medium.com/YKt4lWIAqPb

I just published My Experience With Gamified Learning link.medium.com/y4bB9GnQoPb

Emotional Distress and Its Impact on Immunotherapy Efficacy link.medium.com/MV7QrPVphPb

Leman Biotech _EPFL_China #Meta10-19, #CART Therapy, #Cancer #DLBCL #ALL 100% Complete Response Phase 1 Study. link.medium.com/K850eZ5yfPb

“Learnings of the Bhagavad Gita with Business Relevance:” by Harsha Doddihal Gita Jayanti doddyh.medium.com/learnings-of-t…

Common Sense Oncology link.medium.com/9N3Xju5D4Ob

Forgive, O Lord, my little joke on thee, And I’ll forgive thy great big one on me. Robert Frost

I just published Key Learnings from Women Founders In Switzerland link.medium.com/cFA3OQLIwOb