Chad Hicks

217 posts

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Chad Hicks

Chad Hicks

@HicksChadW

CryoEM Scientist and facility manager at the Boston University Cryogenic EM Core Facility

Katılım Ağustos 2014
214 Takip Edilen217 Takipçiler
Chad Hicks
Chad Hicks@HicksChadW·
@WordenEvan @VAInstitute Congratulations! Those look like very challenging cryoEM structures. I'm excited to read about it!
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Evan Worden
Evan Worden@WordenEvan·
Pleased to present our first preprint on how de novo DNA methylation occurs in di-nucleosomes. Lots of surprising findings about the linker length dependence of DNMT3 binding and activity. A great collaboration with the Peter Jones lab @VAInstitute. tinyurl.com/47pmv7hy
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Cynthia Wolberger
Cynthia Wolberger@CWolberger·
Would be great if someone could share some cat videos right now.
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Chad Hicks
Chad Hicks@HicksChadW·
Feeling incredibly grateful today for the opportunity to vote in a free and fair election. Democracy is on the ballot. Use it or lose it...
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Chad Hicks
Chad Hicks@HicksChadW·
@Adrian_H Loading control band "smiling" upward smearing at far left and right wells are normal. "Smiling" artifacts in the middle wells is unusual and indicates that these are two gels spliced together?
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Adrian H
Adrian H@Adrian_H·
🤔
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derek guy
derek guy@dieworkwear·
the only 'stocks i care about
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Chad Hicks
Chad Hicks@HicksChadW·
@peiferlabunc @CWolberger You can trace the general path of the disordered H3 tail to the Haspin active site in a low-pass filtered map! The final few residues that make contact with the active site are well resolved after performing a local refinement of Haspin alone!
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Chad Hicks
Chad Hicks@HicksChadW·
@FilipGarbicz Thank you!! We should be able to release the three PDBs soon!
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Filip Garbicz
Filip Garbicz@FilipGarbicz·
@HicksChadW Amazing, I've been working with Haspin a little bit. Will there be a PDB attached?
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Chad Hicks
Chad Hicks@HicksChadW·
I am thrilled to share a preprint of my PhD project revealing the cryoEM structure of Haspin kinase bound to nucleosome at a DNA supergroove! biorxiv.org/content/10.110…
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Chad Hicks
Chad Hicks@HicksChadW·
@AHollandLab @CWolberger @SanimRahman4 This project was conceptualized as a way to provide a useful and fun cryoEM experience to Hopkins Summer Academic Research Experience (SARE) scientist Stacy Vasquez during her senior year of high school last summer. We were really surprised by the results...
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Chad Hicks
Chad Hicks@HicksChadW·
I am very grateful to the amazing scientists and coauthors. You are all awesome, and I am so proud of our discovery! @AHollandLab (Colin Gliech), @CWolberger lab (Xiangbin Zhang, @SanimRahman4), Baltimore Polytechnic Institute (Stacy Vasquez).
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Cynthia Wolberger
Cynthia Wolberger@CWolberger·
Officially Dr. Hicks, now with the diploma to prove it! ⁦Congratulations @HicksChadW⁩ !
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Chad Hicks
Chad Hicks@HicksChadW·
@dabiophysicist Thanks! Many of the nicest looking pictures of the eclipse are also composite images from many different photos. These here are single photo images, so that's probably why they look more natural!
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Daniel Asarnow
Daniel Asarnow@dabiophysicist·
@HicksChadW These are great, thanks! I find most photographers focus on one aspect, instead of approximating the naked eye view (which is very difficult). Your no. 1 here is among the better ones
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Chad Hicks
Chad Hicks@HicksChadW·
I managed to get some awesome photos of the 2024 solar eclipse. What an amazing experience... The reddish solar prominence at the bottom of the sun (which was visible to the naked eye) is ~40,000mi long or ~5 times the diameter of Earth 🤯
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