Existential Hope

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Existential Hope

Existential Hope

@HopeExistential

Existential Hope is a program by @foresightinst for thinking big about what positive futures are possible with science and tech.

Katılım Eylül 2021
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Existential Hope
Existential Hope@HopeExistential·
What’s the best technology that doesn’t exist yet? Most funding is pouring into AGI right now. But there's much more being built that could be truly transformative, and almost no one is paying attention. Some technologies can guide funding, coordination, and what feels possible long before they're built. The internet did; so did the Human Genome Project; AGI is doing it now. @michael_nielsen calls these hyper-entities. We went looking for new ones in 100+ podcasts, worldbuilding scenarios, and essays from Existential Hope, a project that has been mapping positive futures for over 5 years. From 300+ ideas, here are the 10 we’re most excited about: • Chemputing – Chemistry made programmable: write code, a robot runs the reaction, same result everywhere. • Machine-readable science – Scientific publishing made usable to AI, so that it can verify claims and build on findings directly. • Open science networks – Infrastructure that rewards scientists for sharing data and replicating results, not just publishing first. • Epistemic stack – A system that lets anyone trace a claim (in science, policy, the news, etc) through chains of evidence. • Fiduciary AI assistants – An AI assistant that is bound to you and legally required to act in your interest. • Immune-computer interface – Continuous real-time monitoring of your immune system. • Conflict de-escalation protocol – AI mediation that finds fair outcomes before disputes escalate. • Deep fission – Car-sized nuclear reactors built to be highly safe and to run autonomously for decades, installed underground. • Digital twins – Living simulations of cities, ecosystems, supply chains, and other complex systems to test decisions before committing. • Interspecies communication – Decoding what other species communicate to each other. More info in the reply ↓
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Existential Hope@HopeExistential·
🥈 Second place: REWIRE Attention spans are declining among teenagers, and that has real consequences for learning, memory, and comprehension. A student from Arizona College Prep High School built a web app called REWIRE that monitors brainwave activity in real time using data from a non-invasive electroencephalogram. When the app detects that your focus is dipping, it delivers a small audio or visual cue to re-engage you, personalized to your own baseline. In a study with 49 participants across 245 sessions, the group using REWIRE showed significant improvements in reading focus, comprehension, and spatial memory compared to the control group. The idea is that consistent, timely feedback during moments of mental drift can actually strengthen attention over time, not just catch lapses as they happen. More details: isef.net/project/beha04…
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Existential Hope
Existential Hope@HopeExistential·
🥇 First place: The Virtual Cell 2.0 Finding the right drug combination for a cancer patient is hard. The number of possible combinations grows fast, and testing them all in a lab isn't realistic. A student from Stanton College Preparatory School built an AI-assisted simulation system that models how a specific cancer cell will respond to different drug combinations based on its genetic and protein profile. The system generates millions of possible biochemical reactions, then trims them down based on the cell's actual molecular makeup. It can run a full simulation in about 35 seconds. Tested across 12 cancer cell lines and 12 targeted therapies, the model's predictions matched real lab results with 95%+ accuracy. The goal: help oncologists prioritize which drug combinations are most likely to work for a specific patient's tumor, before ever running a trial. More details: isef.net/project/cell00…
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Existential Hope
Existential Hope@HopeExistential·
What kind of scientific research doesn’t just solve a narrow problem, but helps build toward a future we really want to live in? That’s the question @foresightinst brought to ISEF 2026, the world's largest high school science fair run by @Society4Science. We gave out the Existential Hope Award to projects showing great potential to contribute to a positive future for humanity, with bonus points for interdisciplinary thinking and awareness of broader societal implications. This year's winners: - First place: an AI system that simulates how cancer cells respond to drug combinations, to help match patients to the right therapies faster - Second place: a brain-monitoring app that detects when your attention is fading and nudges it back in real time Congratulations! More details about the winner projects below ↓
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Existential Hope@HopeExistential·
Every year the economic gap between the US and Europe grows wider. Progress studies is the field that asks why: why civilizations flourish or stall, and what we can do about it. It has gained real traction in the US, but the conversation is just starting in Europe. Last Monday in Stockholm, we hosted the first in a new salon series to help change that. @johanknorberg talked about why golden ages end and how we can keep Europe’s alive; @StefanFSchubert about why we underestimate progress; and @beatrice_erk about what progress studies is and why Europe needs it. Big thanks to everyone who joined us.
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Existential Hope@HopeExistential·
You'd need 200 Chernobyls a year to kill as many people as fossil fuels. So why are most people so scared of nuclear energy? Last year, @isabelleboemeke broke it down on the Existential Hope podcast. The fear started with Hiroshima and Nagasaki and was consolidated through decades of Cold War anxiety. The data tells a very different story: nuclear is as safe as wind and solar, and safer than hydro. And it could be the key to clean energy abundance. Growing up without reliable electricity in rural Brazil, she saw firsthand what energy scarcity looks like, and why degrowth isn't the answer.
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Existential Hope@HopeExistential·
AI could strengthen how societies make decisions together, or it could accelerate power concentration and erode democratic institutions. Which way things go isn't predetermined. On July 5 in Seoul, with @ForesightInst and @CooperativeAI we are hosting a full-day workshop to connect ~50 researchers, builders, and practitioners working on this problem. Three focus areas: AI tools for collective deliberation, governance under rapid AI progress, and democratic practices that are working (or not). The goal: surfacing concrete collaborations, not just exchanging ideas. Application link in the reply ↓
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Existential Hope@HopeExistential·
@JMark4321 @davideagleman Fair question. The goal with this is not to deny someone's death, but finding ways that can help some of us deal with the grief.
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Existential Hope@HopeExistential·
Can AI help us process grief? Neuroscientist @davideagleman used an AI tool to recreate his late father's voice. He explains the science behind why losing someone you love hurts so much, and why hearing them say new things feels so powerful.
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Existential Hope@HopeExistential·
Most AI safety work is focused on what AI shouldn't do: no toxic content, no dangerous help, no rule-breaking. But a new paper argues that's only half the job. @RubenLaukkonen, @sebkrier and colleagues call the alternative "positive alignment": designing AI not just to avoid harm, but to actively support human flourishing. What that means in practice: -> A good life involves more than feeling fine in the moment. A positively aligned AI would act less like a shortcut machine and more like a wise partner that helps you grow and reach your long-term goals. -> Different cultures have different ideas of what a good life looks like. AI systems need to be customizable enough that communities can shape them to reflect their own values, not just adopt a one-size-fits-all default. -> Building this kind of AI requires changes to the whole training process, including feeding AI high-quality data that reflects diverse cultural ethics, not just filtering out bad content. What would it look like if we stopped treating AI as just an obedient tool, and designed it around the question "what helps humans truly thrive?" instead?
Ruben Laukkonen@RubenLaukkonen

What is intelligence for? In a rare collaboration between top universities and 3 frontier labs, we all agree that alignment should move beyond pathologizing to a positive focus on flourishing. We need north stars not just barbed wire. A close historical analogue comes from psychology. For much of the twentieth century, mainstream psychological science organized its aims around diagnosing, predicting, and treating dysfunction: depression, anxiety, psychosis, addiction, and other forms of impairment. That focus was justified and socially urgent, and it produced progress. Yet the field also discovered a systematic limitation. The constructs and instruments that reliably detect pathology do not, by default, specify what counts as a life well-lived. The turn toward positive psychology expanded the scientific target space by developing distinct theories, taxonomies, and measures for wellbeing, strengths, virtue, purpose, wisdom, meaning, and prosocial functioning, alongside interventions to boost these capacities beyond the status quo. As AI becomes embedded all over society and everyday sensemaking, a solely negative posture risks optimizing our information ecology for risk avoidance rather than human development. It may reduce catastrophic errors but leave agents in a local optimum of superficial and `soulless' assistance, where subtle misalignments abound. It also reveals that alignment is not a purely technical problem. We have to cut across vast disciplines because questions about the good life demand insights from philosophy, pychology, neuroscience, economics, and beyond. We need to work together to build AI systems that explicitly understand, model, and enhance human, animal, and ecological flourishing. The core challenge is therefore to build systems that can represent and reason about wellbeing as a structured manifold of human goods, trade-offs, and temporal dynamics, while enabling individuals and communities to retain agency over what counts as better in their context. While some may explicitly desire a system that is strictly and indiscriminately instruction-following, others must have the genuine option to choose systems configured to support their long-term growth or specific ethical commitments. This distinguishes *consented guidance*, where a user authorizes a system to help align their immediate actions with their higher-order goals, from *technocratic imposition*, ensuring that the pursuit of flourishing remains an exercise of, rather than an infringement upon, human agency. It gives me optimism that we found common ground on such a profoundly complex issue as the end game(s) of AI. Because when learning become cheap, we need to take a serious look at what intelligence is actually for.

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Existential Hope
Existential Hope@HopeExistential·
Most AI futures give us two options: mass unemployment, or a government handout to soften the blow. But what if there's a third option, one centered on completely new categories of creative work that don't yet exist, where people get paid for contributing to AI rather than replaced by it? In this episode, we talk with Jaron Lanier, pioneer of virtual reality and scientist at Microsoft Research. He proposes a radically different way of thinking about AI, and unpacks its consequences from AI safety to the future of the economy. Links below! Timestamps: 0:00 Cold open 0:50 40 years in Silicon Valley: how tech became a pseudo world government 4:19 Self-driving cars, Tesla, and the moral paradox of tech progress 7:13 Why "artificial intelligence" is a marketing term, and how you should think about it instead 15:16 AI as human collaboration: what it makes possible and how it makes you a better user 21:37 From the Turing test to the truth crisis: how science shifted from seeking truth to performing it 25:36 Data dignity: going back to the people to solve AI's biggest safety failures 32:55 The alternate future worth building, and challenging the AI orthodoxy 38:41 Why UBI won't work and why a creativity-based economy is more stable 45:20 How to be an optimist about technological progress while acknowledging the risks
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Existential Hope
Existential Hope@HopeExistential·
Inspiring to see that teaching AI *why* ethical behavior matters works better than just training it to avoid bad outputs. @AnthropicAI also found that Claude 4’s blackmailing behaviors were likely caused by internet data portraying AI as stereotypically evil. That motivates us even more to create positive, alternative visions of what AI can be.
Amanda Askell@AmandaAskell

Alignment research often has to focus on averting concerning behaviors, but I think the positive vision for this kind of training is one where we can give models and honest and positive vision for what AI models can be and why. I'm excited about the future of this work.

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Existential Hope
Existential Hope@HopeExistential·
Submit here: #AIFutures" target="_blank" rel="nofollow noopener">worlds.existentialhope.com/#AIFutures Rules - Who can enter Anyone aged 16 or older. Under 18s need parent or guardian permission. - Course requirement Complete the free Worldbuilding Hopeful Futures with AI course before submitting. - What to submit Use the submission form to answer open-ended questions and upload media. You can submit as an individual or as a team. - Use of AI AI tools are allowed. - Originality The world should be your own. Don’t submit work you’ve published elsewhere or work that’s substantially someone else’s. - Deadline 30 June 2026, 23:59 anywhere on earth (UTC-12). - Review The Existential Hope team reviews. Winners announced mid-July 2026. Prizes $5,000 - Best overall world $1,000 - Best visuals $1,000 - Best transformative technology $1,000 - Most inspiring vision $1,000 - Best transformed sector $1,000 - Best institution
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Existential Hope@HopeExistential·
While everyone's focused on how our future with AI could go wrong, we're giving $10K to young people who can show us where we should be going. The AI Futures Challenge 2026 is open. Take our free 1.5hr course on Udemy, build a realistic world where AI transformed our lives for the better, and submit it for a chance to win. → $5K grand prize + 5 × $1K bounties → Deadline: 30 June → No prior knowledge required Know a student or young creative who'd love this? This one is for them. Rules and submissions link in the reply ↓
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Existential Hope@HopeExistential·
What if the history of human invention looked like a Civilization tech tree? That's exactly what @borismus built, and we love how the result looks. He turned Asimov's encyclopedia of scientific history into an interactive visualization that maps out connections across 597 inventions, from ancient times to 1850. You can filter by field, search by topic, and trace how something like the steam engine eventually leads to transatlantic travel. Links below!
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