Johns Hopkins Pain

Outstanding Grand Rounds with Dr. Michele Curatolo on human-centric molecular pain neuroscience. A rigorous, integrative framework linking pain neurobiology to clinical phenotypes and potential treatment strategies. #PainResearch #Neuroscience #TranslationalMedicine

Honored to host ACCM Grand Rounds with Michele Curatolo, MD, PhD—a powerful reminder that pain is never “one thing,” but a complex, human experience shaped by timing, character, sensitivity, and context. Thought-provoking science. Clinical relevance. Inspiring perspective.

Online ahead of print in Molecular Pain: T cells shape paclitaxel-induced neuropathic pain in a modality- and phase-specific manner, with a selective role in cold hypersensitivity. journals.sagepub.com/doi/abs/10.117…

Nearly 1 in 4 U.S. adults live with chronic pain. At Maimonides, we're proud to invest in patient-centered care that offers options beyond opioids. CNN's @drsanjaygupta features Dr. Sergey Motov & our ER team in It Doesn't Have to Hurt - Sept. 7, 9PM ET/PT. @maimoems @pained

"Take the time to listen and validate your patients’ pain experiences. Learning how the pain affects their daily activities may more precisely direct therapy."- @DoctorSivaMD @HopkinsPain @HopkinsACCM @RAPMOnline #MedTwitter closler.org/lifelong-learn…

Resiniferatoxin (RTX), a plant-derived compound, could pave the path for easing cancer-related pain. Recent NIH research shows that after a single injection of RTX, patients with advanced-stage cancer experienced a decrease in severe pain and the use of pain-relieving opioids. Read more: go.nih.gov/fiMMo2Q.

Chronic pain remains a major challenge—despite scientific progress, many patients still face delays, stigma, and limited options. I spoke with @Newsweek about why better science hasn’t always led to better care. newsweek.com/2025/08/22/chr… #ChronicPain #PainResearch #HealthPolicy

💊 Lost in conversion? Converting intrathecal to oral opioids isn't as simple as 1:300. This RAPM case report shows: 🧩 Real-life ratios = 1:2 to 1:12 ⚠️ 1:300 may be dangerously outdated 🔗 doi.org/10.1136/rapm-2… By @talktoratan @DoctorSivaMD #Opioids #RAPM

#regionalanesthesia #pain @ASRA_Society Consensus Practice Infection Control guidelines: 👇🏿 Check out: rapm.bmj.com/content/early/… @DProvenzanoMD Full article: rapm.bmj.com/content/early/… @NarouzeMD @RAPMOnline @Ropivacaine @MayoPainMed @ESRA_Society @dr_tinadoshi @rakesh6282

It is unbelievable that when I started my lab 11 years ago people referred to itch as a "niche" therapeutic domain. Look at the monthly Rx of Ebglyss and Adbry (anti-IL-13 mAb) and Nemluvio (anti-IL-31RA mAb) since launch. Dupixent (anti-IL-4R mAb) is not on this chart because it's so far along.

Just arrived in my office-3rd edition of my book. New chapters, my original art, patient stories, and case studies. Available in September....#kathleensluka #slukaart #painscience ⁦@UIowaPTRS⁩ ⁦@uihealthcare⁩ ⁦@IowaMed⁩ ⁦@UIowaNeuro⁩

What do you think the next step will be in mechanism-based nonopioid analgesic #painmanagement? Zeng et al. review the challenges and breakthroughs, as well as the need for pharmacodynamically distinct multimodal interventions in @jclinicalinvest bit.ly/44cmzJ8 #PRF

Nearly 19 million U.S. children—1 in 4—lived with at least one parent or primary caregiver who had a substance use disorder in 2023. The findings highlight the need for treatment for parents and interventions for families affected by substance use disorders. bit.ly/3TwEcx2

The @US_FDA has created a new program that will speed up the approval of new drugs before clinical trials are even completed, and without the usual oversight by FDA staff and advisors. What could possibly go wrong? @DrMakaryFDA bit.ly/4jXhsB5

So pleased this one now out with the amazing @DrSFink Interoception and pain: body–mind integration, rupture, and ... : PAIN journals.lww.com/pain/fulltext/…

Norepinephrine and CXCL16 are co-released from the terminals of sympathetic nerve fibres in the dorsal root ganglion & synergistically contribute to the maintenance of neuropathic pain #pain #laboratory #cytokines bjanaesthesia.org/article/S0007-…

We are sad to announce that Dr. Ronald D. Miller has passed away. He served as our chair from 1984 until 2008, and was one of the most successful physician-scientist-leaders in the field’s history. Read more about his remarkable life and legacy: anesthesia.ucsf.edu/news/rememberi…

MEMBER SPOTLIGHT: @DoctorSivaMD is shaping the future of #neuromodulation! 🔬✨ As Director of Neuromodulation at @HopkinsMedicine, he is dedicated to leveraging #neurostimulation for patients with chronic pain & non-traditional indications. Read more: neuromodulation.org/member-sivanes…

🚨Time to rethink the SCS trial-to-implant ratio?🚨 With recent implant rates >80%, are trial-to-implant ratios are still meaningful? Or is it time to update utilization metrics to include explant and per-capita ratios? @DoctorSivaMD @Ryan_S_DSouzaMD bit.ly/3QSdihN

ASRA Pain Medicine consensus practice infection control guidelines for regional anesthesia and pain medicine rapm.bmj.com/content/early/… @ASRA_Society @RAPMOnline @DProvenzanoMD @SLKoppMD @dr_tinadoshi @AmyPearsonMD @amit_pawa @ajrmacfarlane @KalagaraHari @NarouzeMD @DoctorSivaMD