Hsieh Lab

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Hsieh Lab

Hsieh Lab

@HsiehLab

A lab @FredHutch obsessed with translation control and its impact on health and disease. #mRNAtranslation #prostatecancer #bladdercancer #physicianscientist

Seattle, WA Katılım Ocak 2019
609 Takip Edilen2K Takipçiler
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Hsieh Lab
Hsieh Lab@HsiehLab·
Ever wonder how toggling protein synthesis impacts cellular identity? Dr. Rashmi Mishra @HsiehLab did and through a clever drug screen discovered that the cap-binding domain of eIF4E regulates lineage fate in prostate cancer. Story hit newsstands today: jci.org/articles/view/…
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Petros Grivas
Petros Grivas@PGrivasMDPhD·
Welcome Dr. Jiang! Thanks @rarengan for your leadership & support for Rad Onc growth across cancer types! @UW @fredhutch @DrOmarMian @WinstonVuong @MartinMaMDPhD @HutchPresident @mshadman @VenurVyshak @HsiehLab @AMFShepherd @RahulBanerjeeMD @DimaDanai @spsutkaMD @SteveBlinka
Ramesh Rengan@rarengan

Please join me in welcoming Dr. Yuyan Jiang to @UW @fredhutch RadOnc and Human Biology as an Assistant Professor. Her work on LYTACs and gold-siRNA supraclusters will advance our precision rad onc research program. @UWMedicine @uwradonc

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Fred Hutch Cancer Center
Fred Hutch Cancer Center@fredhutch·
Happy 4th of July! Wishing you a happy and safe celebration full of fun and #sunscreen. ☀️
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Shawn Lupold
Shawn Lupold@lupold_lab·
Thrilled to begin as Editor-in-Chief of The Prostate! Looking forward to working with an outstanding team: @EAntonarakis, @BurcuDarst, Jun Luo, @lemonrock_MD, and @ArunRaiMD. Grateful for Sam Denmeade's exceptional leadership & mentorship over his 6-year tenure as EIC.
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SheqLab
SheqLab@ShechnerLab·
Delighted to announce that, as of today, I’ve been officially promoted to Associate Professor (without Tenure) of Pharmacology @UW I am deeply endebted to my colleagues, mentors, and the talented trainees in my group. Working with you has been the highlight of my career!
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Science in Seattle
Science in Seattle@science_seattle·
Guess who's back! 🧪 The annual Mutational Scanning Symposium, hosted by the Atlas of Variant Effects Alliance, is returning to Seattle on June 23 – 25, 2027 for its 10th anniversary. Learn more: bit.ly/3QXiGEb
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Jelani Zarif Lab
Jelani Zarif Lab@Zarif_Lab·
After several submissions, I am truly elated to receive our second R01 research grant from the @theNCI! This innovative prostate cancer research would not be possible without my dedicated team of graduate students, postdoc fellows, and collaborators here @HopkinsMedicine
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Fred Hutch Cancer Center
Fred Hutch Cancer Center@fredhutch·
.@ShankaranVeena, co-director of the Hutchinson Institute for Cancer Outcomes Research (HICOR), has been awarded the newly established Lert Family Endowed Chair, accelerating research to understand and reduce the financial burden of cancer. 🔗 bit.ly/4emr3Rm
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Journal of Clinical Investigation
Journal of Clinical Investigation@jclinicalinvest·
@HsiehLab @fredhutch Mishra et al. also showcases HPG-TMT mass spectrometry, which specifically captures newly synthesized proteins through HPG pulse labeling and pulldown.
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Nima Sharifi
Nima Sharifi@NimaSharifiMD·
1/ For 15 years we studied how slow vs fast forms of HSD3B1 work in prostate cancer, drive ADT resistance & lethality. Why is the fast #HSD3B1 so common? Does it do something other than cause lethal prostate cancer? YES! Here's the story @jclinicalinvest! jci.org/articles/view/…
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Fred Hutch Cancer Center
Fred Hutch Cancer Center@fredhutch·
Fred Hutch at #ASCO26: Dr. Sara Hurvitz presents results from the Phase 3 VIKTORIA-1 study, evaluating gedatolisib plus fulvestrant and palbociclib versus standard of care in patients with HR+/HER2−, PIK3CA-mutant advanced breast cancer.
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Karuna Ganesh
Karuna Ganesh@KarunaMDPhD·
We are thrilled to share our latest work out today @Dev_Cell! Appendiceal adenocarcinoma (AC) is a rare, aggressive cancer that frequently spreads to the peritoneum. Until now, lack of robust preclinical models has severely limited drug discovery. cell.com/developmental-…🧵👇 🔗
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Hutch Basic Sciences
Hutch Basic Sciences@HutchBasicSci·
Today we're celebrating the achievements of three Basic Sciences Faculty! Dr. Jesse Bloom (@jbloom_lab) for being elected to @theNASciences, Dr. Susan Parkhurst for being named a fellow of @aaas, and Dr. @ToshioTsukiyama for being appointed to the Lycette Endowed Chair.
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Fred Hutch Cancer Center
Fred Hutch Cancer Center@fredhutch·
Congratulations to Dr. Toshio “Toshi” Tsukiyama, professor and associate director of the Basic Sciences Division, on receiving the inaugural David and Deborah Lycette Endowed Chair for Cancer Research. Read more: bit.ly/4eZye3W
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Fred Hutch Cancer Center
Fred Hutch Cancer Center@fredhutch·
Congratulations to Drs. Pallabi Mustafi and @RubenRaychaud, who recently received Young Investigator Awards from the Prostate Cancer Foundation for their work investigating epigenetic features of aggressive prostate cancer. Read the full story: bit.ly/4nGuRRB
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Petros Grivas
Petros Grivas@PGrivasMDPhD·
@FDAOncology approved atezolizumab as adjuvant Tx in resected MIBC based on ctDNA #IMVigor011 (IO-naive patients). The candidate population is shrinking due to EV-303, EV-304, NIAGARA trials data but exists @BladderCancerUS @HsiehLab @spsutkaMD @OAlhalabiMD @shilpaonc @DrOmarMian
Andrea Apolo, M.D.@apolo_andrea

US FDA Approves #atezolizumab for Adjuvant Muscle-Invasive Bladder Cancer With #ctDNA-Guided Treatment based on data from #IMvigor011. This is the first approval in #BladderCancer using ctDNA. A step forward in our field. - businesswire.com/news/home/2026…

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Keşfet

@rarengan @UW @fredhutch @DrOmarMian @WinstonVuong @MartinMaMDPhD @HutchPresident @mshadman