

Human Ecosystems @EMBL
162 posts

@HumanEcosystemz
Developing a complete understanding of how the physical, biological, and social environment impacts human biology at the molecular level @EMBL














To close 2023, we present our work on #osteosarcoma genome and clonal evolution biorxiv.org/content/10.110… How does #osteosarcoma arise? What rearrangement mechanisms cause some of the most complex #chromothripsis events seen in human cancer? Does chromothripsis occur subclonally?👇



Want to hear more about this kind of work from @isidrolauscher? He'll be speaking at our ecDNA conference in London this June 🗓️ Learn more and register: bit.ly/ecDNA2025









📢 Preprint! Does the environment of a father before conception influence offspring? Even more, how do paternal genetics & age interact with exposures to affect F1 outcome? We tested this systematically, with intriguing findings & some cautionary tales biorxiv.org/content/10.110…










