KIM Hyojun

Our new preprint has come out! Cells get heavier and heavier with growth-induced pressure..🏋️

An elegant model: - TF binding events on nucleosome-free DNA are independent. - Yet, the activation domains of TFs recruit cofactors that destabilize nucleosomes, resulting in cooperative TF binding. - Average TF occupancy linearly determines promoter activity

@Bunshu23 Haha lovely. can't wait for that!

@Hyojun_Kim_ Gigantic thanks! I'm planning to contact you and Morgan to announce this news and will wait for you in Okinawa.

10月より OIST で独立グループを立ち上げます。群星（ぶりぶし）フェローという研究集中ポジションで、任期最大5年のPIです。 oist.jp/research/burib…

🚨🚨Please RT! 📢📢 Still time to submit short talk abstract for EdinPBS2025! Five themes this year: · Mechanobiology · Protein pattern formation · 4D Genome · Stochastic biology · Biohydrodynamics bit.ly/EdinPBS2025

How to "program" living cells.🧫 In 2000, physicists ( @ElowitzLab) made bacteria blink on-and-off every 150 minutes. Their experiment, which blended mathematics and wet-lab methods, launched the field of synthetic biology. Learn how they did it in my first interactive story.

@yura__song @CedricBlanpain @Alessia100nze @ChenJiang919 Big congrats Yura👏

Our paper is finally out! We discussed how the Collagen signalling and ECM stiffness could regulate multipotency of glandular epithelia! Thanks to @CedricBlanpain for supervising this amazing project and thanks to @Alessia100nze and @ChenJiang919 :) nature.com/articles/s4146…

"One email at a time, one informational interview after another, I became comfortable, confident, and strategic in building my network of mentors." One mentor isn’t enough, writes @DrErikaMoore in this #ScienceWorkingLife essay from 2021. bit.ly/48iBjGZ #ScienceMagArchives

Latest work from our group @Esoftbio @NCBS_Bangalore, led by Sree @padmanabh97, is out today in @NatureComms! In colab with @DeepaAgashe @c_kurzthaler we report that the physical confinement acts as a selective pressure on bacterial growth in 3D! [1/16] tinyurl.com/mvbdm3ue

Cell-cycle-dependent mRNA localization in P-bodies dlvr.it/TG5Fyd

Metabolism and epigenetics sync up! 🌀 Histone acetylation not only activates genes but also acts as an acetate reservoir. #Metabolism #Epigenetics #HistoneAcetylation. Thank you @KirmizisLab! More details @TrendsBiochem authors.elsevier.com/a/1k3PJ3S6GfQa…

This paper highlights how error bars are often misunderstood, especially regarding statistical significance. Let's explore the key points to clarify these misconceptions. #Statistics #DataScience #Research #OpenScience nature.com/articles/nmeth…

Timescales in Cell Biology

How do cells response to withdrawal of amino acids? It depends on the amino acid. ◼️Lysine withdrawal causes immediate cell-cycle stalling while the withdrawal of other amino acids allow for completion of additional cell cycles.

@Bunshu23 Haha they will love that 👍👍

@Hyojun_Kim_ Thanks! I'll bring your note, which you gave me on the last day at LAAS, to use some Korean phrases.

I will be at KASIT, South Korea, in October to start our collaboration work. We're looking into bacteria in a more physiological environment to understand their physiology in hosts and regulate their growth in situ. Can't wait!

Fantastic work from @laure_le_blanc's PhD, and a great collaboration with @DumenilLab and @DariaBonazzi! Bacteria get more crowded under confinement, decreasing biosynthesis and growth. But they still divide and become extra small! Check out to see how they perform under pressure

Woohoo! "A guide to single particle tracking" is now online! Together with @Francois__Simon & @S_vanTeeffelen, we share our thoughts on going beyond MSD analysis in Nature Reviews Methods Primers. doi.org/10.1038/s43586… Free read link: rdcu.be/dTKHd

@yura__song Thanks :)

@Hyojun_Kim_ Ohhhhh deserved!!!

Our new preprint has come out! Cells get heavier and heavier with growth-induced pressure..🏋️